Results 21 to 30 of about 655,342 (154)

High-Throughput MICA/B Genotyping of Over Two Million Samples: Workflow and Allele Frequencies

Frontiers in Immunology, 2020
MICA and MICB are ligands of the NKG2D receptor and thereby influence NK and T cell activity. MICA/B gene polymorphisms, expression levels and the amount of soluble MICA/B in the serum have been linked to autoimmune diseases, infections, and cancer.
Anja Klussmeier, Carolin Massalski, Kathrin Putke, Gesine Schäfer, Jürgen Sauter, Daniel Schefzyk, Jens Pruschke, Jan Hofmann, Daniel Fürst, Daniel Fürst, Raphael Carapito, Seiamak Bahram, Alexander H. Schmidt, Alexander H. Schmidt, Vinzenz Lange   +14 more
doaj   +1 more source

Polymorphism of KIR2DL4 gene among northern Chinese Han population

Zhongguo shuxue zazhi, 2022
Objective To investigate the polymorphism of KIR2DL4 gene in northern Chinese Han population. Methods A total of 327 DNA samples were isolated by magnetic beads from unrelated individuals of northern Chinese Han population.
Zhichao YANG, Hao CHEN, Li NING, Ying LIU, Zhihui DENG   +4 more
doaj   +1 more source

Analysis of β-casein gene for A1 and A2 allelic variants in Holstein-Local crossbred cattle of Bangladesh using allele-specific PCR

Journal of Advanced Biotechnology and Experimental Therapeutics
Beta-casein (CSN2) is one of the important bovine milk proteins synthesized by β-casein gene. The aim of this study was to investigate the A1 and A2 allelic variants of CSN2 gene in Holstein-Friesian and Local (HF×L) crossbred cattle of Bangladesh ...
Mahfuza Ahmed Safa, Monira Akter Mou, Md. Forhad Ahmed Hridoy, Sadia Afrin Siddiqua, Abul Kashem Fazlul Haque Bhuiyan, Mohammad Shamsul Alam Bhuiyan   +5 more
doaj   +1 more source

Modern Genetic Education: How Does It Meet Students’ Requests?

Высшее образование в России, 2022
The role of genetics in modern society is growing, which makes new demands on the quality of training specialists in this field. The article considers the results of the student survey carried out at universities universities of the Republic of ...
T. A. Sedykh, L. A. Amirova, L. A. Gaysina, G. F. Galikeeva, A. I. Fazlutdinova, N. V. Sukhanova   +5 more
doaj   +1 more source

Impact of the CACNA1G rs757415 polymorphism on grey matter volume in patients with bipolar disorder

Sichuan jingshen weisheng
BackgroundBipolar disorder is a severe mental disorder characterized by cycling between mania/hypomania and depression， yet its underlying pathophysiological mechanism remains unclear.
Cheng Xiaofei, Yang Qian, Nie Yirou, Zhang Mengmeng, Xie Yi, Li Mingli   +5 more
doaj   +1 more source

Monitoring for the genetic structure of Mezen breed of horses in terms of DNA microsatellites

Вавиловский журнал генетики и селекции, 2021
Mezenskaya horse (Mezenka) is Russia’s aboriginal breed. It is a domestic selection in the northern territories of Arkhangelsk region. The breed is perfectly adapted to the conditions of the Far North, and has a number of valuable economic and biological
N. V. Vdovina, I. B. Yuryeva
doaj   +1 more source

HLA-A and -B alleles and haplotypes in hemochromatosis probands with HFE C282Y homozygosity in central Alabama

BMC Medical Genetics, 2002
Background We wanted to quantify HLA-A and -B allele and haplotype frequencies in Alabama hemochromatosis probands with HFE C282Y homozygosity and controls, and to compare results to those in other populations.
Barton James C, Acton Ronald T
doaj   +1 more source

Understanding Cancer Through the Lens of Epigenetic Inheritance, Allele-Specific Gene Expression, and High-Throughput Technology

Frontiers in Oncology, 2019
Epigenetic information is characterized by its stable transmission during mitotic cell divisions and plasticity during development and differentiation. This duality is in contrast to genetic information, which is stable and identical in all cells in an ...
Maxwell P. Lee
doaj   +1 more source

Genome-wide Identification and Functional Analyses of the 5-O-Glucosyltransferase Family Reveal Its Potential Roles in Anthocyanidin Diglucosides Synthesis of Grape Skins with Vitis amurensis Pedigree

Journal of the American Society for Horticultural Science
Vitis amurensis grape cultivars and hybrids are mainly used to make wines in Northeast Asia with a cold winter. Anthocyanidin glucosylation at 5-O position catalyzed by 5-O-glucosyltransferase (5GT) in grape skins is crucial for color stability of red ...
Lei Zhu, Yunhua Chen, Yunqing Liu, Dandan Li, Yiming Yang, Yuanyuan Wang, Yunting Liu, Mingjie Wang, Jingyu Xu, Xixi Hu   +9 more
doaj   +1 more source

ABCA1 rs1883025 and CYP4F2 rs2108622 Gene Polymorphism Association with Age-Related Macular Degeneration and Anti-VEGF Treatment

Medicina, 2021
Background and Objectives: The age-related macular degeneration (AMD) pathophysiology is multifactorial, as it consists of interactions between aging, genetic, and environmental factors.
Ruta Mockute, Alvita Vilkeviciute, Vilma Jurate Balciuniene, Reda Zemaitiene, Rasa Liutkeviciene   +4 more
doaj   +1 more source