Results 51 to 60 of about 1,163,092 (332)

Association of gene polymorphism with menorrhagia combined with thyroid pathology

Репродуктивная эндокринология, 2020
Purpose of the study: to establish the frequency of alleles and genotypes of GP IIIa gene polymorphism in adolescent girls with uterine bleeding that is concomitant thyroid pathology and conduct a thorough genetic analysis of patients.
O. A. Andriets, O. M. Yuzko, Y. V. Tsysar   +2 more
doaj   +1 more source

Association of SOCS5 gene polymorphism with allergic bronchial asthma [PDF]

Терапевтический архив, 2019
Aim: to study the association of mononucleotide polymorphism rs6737848 SOCS5 gene with the risk of development of allergic bronchial asthma. Material and methods.
A B Averyanov, I I Chercashina, S Yu Nikulina, V N Maksimov, V A Shestovitskiy   +4 more
doaj   +1 more source

HLA-A*11:01:01:01, HLA-C*12:02:02:01-HLA-B*52:01:02:02, Age and Sex Are Associated With Severity of Japanese COVID-19 With Respiratory Failure

Frontiers in Immunology, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing coronavirus disease 2019 (COVID-19) was announced as an outbreak by the World Health Organization (WHO) in January 2020 and as a pandemic in March 2020.
Seik-Soon Khor, Yosuke Omae, Nao Nishida, Masaya Sugiyama, Noriko Kinoshita, Tetsuya Suzuki, Michiyo Suzuki, Satoshi Suzuki, Shinyu Izumi, Masayuki Hojo, Norio Ohmagari, Masashi Mizokami, Katsushi Tokunaga   +12 more
doaj   +1 more source

Quality of life effects of androgen deprivation therapy in a prostate cancer cohort in New Zealand: Can we minimize effects using a stratification based on the aldo-keto reductase family 1, member C3 rs12529 gene polymorphism? [PDF]

, 2016
Background: Androgen deprivation therapy (ADT) is an effective palliation treatment in men with advanced prostate cancer (PC). However, ADT has well documented side effects that could alter the patient's health-related quality of life (HRQoL).
Benjamin, Benji, Ellett, Stephanie, Ferguson, Lynnette R., Goudie, Megan, Han, Dug Yeo, Holmes, Michael, Karunasinghe, Nishi, Keogh, Justin, Lange, Katja, Masters, Jonathan, Wang, Alice, Zhu, Shuotun, Zhu, Yifei   +12 more
core   +2 more sources

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source

Allele Frequencies Database [PDF]

Transfusion Medicine and Hemotherapy, 2014
This review describes a database for the collection, archiving, sorting, searching and display of gene and allele frequencies for immunogenetic genes.
Faviel F. Gonzalez-Galarza, Louise Y. Takeshita, Andrew R. Jones, Derek Middleton   +3 more
openaire   +3 more sources

Allele-Specific Isothermal Amplification Method Using Unmodified Self-Stabilizing Competitive Primers. [PDF]

, 2018
Rapid and specific detection of single nucleotide polymorphisms (SNPs) related to drug resistance in infectious diseases is crucial for accurate prognostics, therapeutics and disease management at point-of-care.
Baum, Jake, Chotivanich, Kesinee, Delves, Michael J, Georgiou, Pantelis, Malpartida-Cardenas, Kenny, Nguon, Chea, Rodriguez-Manzano, Jesus, Yu, Ling-Shan   +7 more
core   +2 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

ABCA1 rs1883025 and CYP4F2 rs2108622 Gene Polymorphism Association with Age-Related Macular Degeneration and Anti-VEGF Treatment

Medicina, 2021
Background and Objectives: The age-related macular degeneration (AMD) pathophysiology is multifactorial, as it consists of interactions between aging, genetic, and environmental factors.
Ruta Mockute, Alvita Vilkeviciute, Vilma Jurate Balciuniene, Reda Zemaitiene, Rasa Liutkeviciene   +4 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source