Results 71 to 80 of about 1,163,092 (332)

Genetic control of sterol esterification in developing wheat endosperm [PDF]

, 1975
1. 1. The action of gene Pln, previously characterized by the sterol ester patterns of mature whole wheat kernels, has been found to be restricted to the endosperm and not to affect the embryo, the pericarp or the seed coat. 2. 2.
Bush, Carbonero, Clayton, Duperon, Duperon, Duperon, Evers, García-Faure, García-Olmedo, García-Olmedo, Goodwin, Grunwald, Grunwald, Grunwald, Hartman, Heftman, Hendrix, Hølmer, Jennings, Katayama, Kazpryk, Kemp, Lowry, Mudd, Skarsaune, Torres   +25 more
core   +2 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Disparities in allele frequencies and population differentiation for 101 disease-associated single nucleotide polymorphisms between Puerto Ricans and Non-Hispanic Whites [PDF]

, 2009
BACKGROUND. Variations in gene allele frequencies can contribute to differences in the prevalence of some common complex diseases among populations. Natural selection modulates the balance in allele frequencies across populations.
Adiconis, Xian, Arnett, Donna, Demissie, Serkalem, Garcia-Bailo, Bibiana, Lai, Chao-Qiang, Mattei, Josiemer, Ordovas, Jose M., Parnell, Laurence D., Shen, Jian, Tucker, Katherine L.   +9 more
core   +3 more sources

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Development of a Providencia stuartii multilocus sequence typing scheme

Frontiers in Microbiology
IntroductionThe Providencia genus is assuming greater clinical relevance among infections caused by Enterobacterales also because of its intrinsic and acquired resistance to last-resort antibiotics. However, despite having been known and studied for over
Gabriele Arcari, Gabriele Arcari, Alice De Francesco, Riccardo Polani, Alessandra Carattoli, Valerio Capitani   +5 more
doaj   +1 more source

Association analysis between the C516T polymorphism in the 5-HT2A receptor gene and schizophrenia Análise de associação entre o polimorfismo C516T do gene do receptor 5-HT2A e esquizofrenia

Arquivos de Neuro-Psiquiatria, 2007
Data from epidemiological studies have demonstrated that genetics is an important risk factor for schizophrenia. Disturbances of serotonergic brain pathways have been implicated in the pathophysiology of schizophrenia.
Vivian Bertola, Quirino Cordeiro, Stevin Zung, Elisabete Cristina Miracca, Homero Vallada   +4 more
doaj   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Profil genetika DNA mikrosatelit kromosom-Y masyarakat laki-laki soroh Kayuan Pasek Catur Sanak Bali Mula

Jurnal Kajian Bali (Journal of Bali Studies), 2017
This research is conducted to find out the genetic profiles of Kayuan clan which is belong to Pasek Catur Sanak Bali Mula, indigenous Balinese people. The DNA profiles is identified by using Microsatellite DNA of Y chromosome.
I Ketut Junitha, Ni Luh Watiniasih, Ni Luh Putu Ria Puspitha   +2 more
doaj  

EcoTILLING-based association mapping efficiently delineates functionally relevant natural allelic variants of candidate genes governing agronomic traits in chickpea

Frontiers in Plant Science, 2016
The large-scale mining and high-throughput genotyping of novel gene-based allelic variants in natural mapping population are essential for association mapping to identify functionally relevant molecular tags governing useful agronomic traits in chickpea.
Deepak eBajaj, Rishi eSrivastava, Manoj eNath, Shailesh eTripathi, BHARADWAJ eCHELLAPILLA, Hari Deo eUpadhyaya, Akhilesh K Tyagi, SWARUP KUMAR PARIDA   +7 more
doaj   +1 more source

Asymptotics of the allele frequency spectrum associated with the Bolthausen-Sznitman coalescent

, 2007
We work in the context of the infinitely many alleles model. The allelic partition associated with a coalescent process started from n individuals is obtained by placing mutations along the skeleton of the coalescent tree; for each individual, we trace ...
Basdevant, Anne-Laure, Goldschmidt, Christina   +1 more
core   +5 more sources