Results 81 to 90 of about 427,317 (231)
Molecular Oncology, EarlyView.The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang +3 more
wiley +1 more source
Frontiers in Plant Science, 2016 The large-scale mining and high-throughput genotyping of novel gene-based allelic variants in natural mapping population are essential for association mapping to identify functionally relevant molecular tags governing useful agronomic traits in chickpea.
Deepak eBajaj +7 more
doaj +1 more source
Association of gene polymorphism with menorrhagia combined with thyroid pathology
Репродуктивная эндокринология, 2020 Purpose of the study: to establish the frequency of alleles and genotypes of GP IIIa gene polymorphism in adolescent girls with uterine bleeding that is concomitant thyroid pathology and conduct a thorough genetic analysis of patients.
O. A. Andriets +2 more
doaj +1 more source
Notes on the Genetics of \u3ci\u3ePhymatodes Testaceus\u3c/i\u3e (Coleoptera: Cerambycidae) [PDF]
, 2017 Phenotype ratio for elytral coloration among reared offspring of Phymatodes testaceus suggests that this trait is controlled by a single gene with a dominant allele producing brown elytra and a reeessive allele for blue elytra. The brown-elytra phenotype
Gosling, D. C. L
core +1 more source
Gene, 2006 Previous studies have reported the existence of eleven different single nucleotide polymorphisms (SNPs) within human PECAM-1 mRNA, several of which have recently been associated with disease. Though SNPs in the PECAM-1 gene have been known for some time, the genetic background on which they exist, and their association into distinct allelic isoforms ...
Thomas M. Ellis +5 more
openaire +3 more sources
Molecular Oncology, EarlyView.Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou +11 more
wiley +1 more source
Keragaman Alel Gadung Liar (Dioscorea bulbifera L.) di Sumatera Barat
Makara Seri Sains, 2007 The variety of six enzymes locus on three populations of Dioscorea bulbifera was revealed using both starch and polyacrilamide gel electrophoresis. Present study showed three polymorphic loci has each 2 alleles with nine total numbers of alleles for all ...
Mansyurdin, Tesri Maideliza
doaj
Arquivos de Neuro-Psiquiatria, 2007 Data from epidemiological studies have demonstrated that genetics is an important risk factor for schizophrenia. Disturbances of serotonergic brain pathways have been implicated in the pathophysiology of schizophrenia.
Vivian Bertola +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa +13 more
wiley +1 more source
Molecular Oncology, EarlyView.FOXL2 c.402C>G mutation drives granulosa cell tumors. Using CRISPR technology, we selectively corrected this mutation, reducing malignancy and increasing sensitivity to dasatinib and ketoconazole. Transcriptomic changes revealed potential therapeutic targets, demonstrating CRISPR's promise for treating this rare ovarian cancer.
Sandra Amarilla‐Quintana +17 more
wiley +1 more source