Results 71 to 80 of about 1,221,818 (402)
Molecular Oncology, EarlyView.The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina +17 more
wiley +1 more source
Plant Varieties Studying and Protection, 2020 Purpose. Determination of molecular genetic polymorphism of lettuce cultivars of Ukrainian breeding by EST-SSR markers. Methods. Molecular genetic analysis, statistical methods. Results.
Н. В. Лещук +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
, 2005 The minimum description length (MDL) principle states that the best model to account for some data minimizes the sum of the lengths, in bits, of the descriptions of the model and the residual error.
Erlich, Henry A. +5 more
core +1 more source
Gene Flow Between Great Lakes Region Populations of the Canadian Tiger Swallowtail Butterfly, \u3ci\u3ePapilio Canadensis\u3c/i\u3e, Near the Hybrid Zone With \u3ci\u3eP. Glaucus\u3c/i\u3e (Lepidoptera: Papilionidae) [PDF]
, 2018 Papilio canadensis were sampled from three locations on either side of Lake Michigan to study gene flow near and through a butterfly hybrid zone. Allele frequencies at four polymorphic enzyme loci, as indicated by allozyme electrophoresis, were similar ...
Crim, Amber +3 more
core +2 more sources
Molecular Oncology, EarlyView.The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang +3 more
wiley +1 more source
Era-like GTP protein gene expression in rice
Brazilian Journal of Biology, 2021 The mutations are genetic changes in the genome sequences and have a significant role in biotechnology, genetics, and molecular biology even to find out the genome sequences of a cell DNA along with the viral RNA sequencing.
X. Zhou +8 more
doaj +1 more source
Patterns of neutral diversity under general models of selective sweeps [PDF]
Genetics September 1, 2012 vol. 192 no. 1 205-224, 2011 Two major sources of stochasticity in the dynamics of neutral alleles result from resampling of finite populations (genetic drift) and the random genetic background of nearby selected alleles on which the neutral alleles are found (linked selection). There is now good evidence that linked selection plays an important role in shaping polymorphism levels
arxiv +1 more source
Exome sequencing of Finnish isolates enhances rare-variant association power. [PDF]
, 2019 Exome-sequencing studies have generally been underpowered to identify deleterious alleles with a large effect on complex traits as such alleles are mostly rare.
Abel, Haley J +42 more
core
Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression. [PDF]
, 2016 The unintended consequences of gene targeting in mouse models have not been thoroughly studied and a more systematic analysis is needed to understand the frequency and characteristics of off-target effects.
Adkisson, Michael +9 more
core +4 more sources