Results 91 to 100 of about 7,354,999 (259)

Nematode in Cockroaches: A Potential Allergen Source

open access: yes
Allergy, EarlyView.
Dongjun Kang   +5 more
wiley   +1 more source

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

open access: yesAllergy, EarlyView.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque   +5 more
wiley   +1 more source

CD27 expression on allergen-specific T cells: A new surrogate for successful allergen-specific immunotherapy? [PDF]

open access: yes, 2012
Comment on: Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy. [J. Allergy Clin.
Traidl-Hoffmann, C.   +3 more
core   +1 more source

Dendritic Cell α‐Ketoglutarate Regulates Tfh Polarization in Allergy

open access: yesAllergy, EarlyView.
Allergen induces a dendritic cell metabolism shift toward glutaminolysis with α‐ketoglutarate as a regulator of Tfh subset polarization. Glutaminolysis is required for DC allergen uptake, co‐stimulatory molecule expression, and CLR expression. Modulation of glutaminolysis, JmjD3 histone demethylation, or HIF‐1α degradation alters Tfh polarization and ...
Anuj Tharakan   +16 more
wiley   +1 more source

Allergen-specific CD8+ T cells and atopic disease [PDF]

open access: yes, 2002
Considerable evidence suggests that IL-10 may have a role in the manifestation of atopic disease. We sought to test the hypothesis that at the single cell level, allergen-specific T cells have diminished IL-10 production capacity in severely affected ...
Powell, Sheila   +6 more
core   +1 more source

Route of Allergen Immunotherapy: A Global Look Into Physicians' Motivations

open access: yesAllergy, EarlyView.
Little is known about the factors driving AIT prescription in clinical practice, including the level of personalization from patient to patient. Patient‐centred factors theoretically would favour SLIT prescription. Doctors’ knowledge, training, and country influence the final decision on the route.
Carmen Vidal   +42 more
wiley   +1 more source

Long-term effects of allergen-specific subcutaneous immunotherapy for house dust mite induced allergic rhinitis

open access: yes, 2017
Background:Allergic rhinitis is strongly associated with the presence of house dust mites. This study investigated the long-term effects of allergen-specific immunotherapy. Allergen-specific immunotherapy was applied over three years. The study was based
Dinç, M. E.   +7 more
core   +1 more source

Classification of Seasonal Allergic Rhinitis Patients by Prospective Patient‐Recorded Symptoms: The @IT.2020 Project

open access: yesAllergy, EarlyView.
Daily prospective symptom reports from participants in this multicentre observational study were compared to retrospective (last 12 months) reports based on ARIA clinical questionnaire. Retrospective reports substantially underestimated, and to a lesser extent overestimated, symptom frequency compared to e‐Diary prospective reports. Since retrospective
S. Dramburg   +56 more
wiley   +1 more source

Skin Abnormalities at Checkpoint Inhibitor Therapy Initiation Are Associated With Skin Rash Development in Oncology Patients

open access: yesAllergy, EarlyView.
Skin tape strip lipidomic analysis revealed preexisting skin barrier lipid abnormalities at day 0 that were further exacerbated after 6 weeks of CPI treatment. Significant changes in skin (but not plasma) proinflammatory cytokines were identified in future ircAE patients after 6 weeks of CPI immunotherapy.
Taras Lyubchenko   +9 more
wiley   +1 more source

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