Results 101 to 110 of about 7,354,999 (259)

Basophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test

open access: yesAllergy, EarlyView.
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan   +5 more
wiley   +1 more source

Single, pauci, and multi-allergen immunotherapy

open access: yesB-ENT, 2018
Single, pauci, and multi-allergen immunotherapy. Objectives: This paper’s aim is to review single, pauci, and multi-allergen immunotherapy. Methods: Search is made through PubMed, Google, Google Scholar and Proquest Central database of the Kırıkkale ...
C. Cingi   +7 more
doaj   +2 more sources

An immunological overview of allergen specific immunotherapy — subcutaneous and sublingual routes

open access: yesTherapeutic Advances in Respiratory Disease, 2009
Allergen-specific immunotherapy remains the most likely effective treatment modality for allergic disorders by targeting the underlying immune mechanisms and possibly causing modifications in the disease course, as well as treating the symptoms ...
Cevdet Ozdemir
doaj   +1 more source

Allergen immunotherapy in atopic dermatitis

open access: yes
The aim of this review is to investigate the possible role of allergen immunotherapy (AIT) for house dust mites in the treatment of atopic dermatitis in adult patients (AD).
Andrzej Bożek   +1 more
core   +1 more source

Efficacy and Safety of Intralymphatic Immunotherapy With Grass Allergoid and Microcrystalline Tyrosine: A Double‐Blind Randomised Placebo‐Controlled Trial

open access: yesAllergy, EarlyView.
This is the first randomised placebo‐controlled trial of intralymphatic immunotherapy using a microcrystalline tyrosine‐adjuvanted grass pollen allergoid. Three ultrasound‐guided ILIT injections were well tolerated and reduced combined symptom‐medication scores compared with placebo. The findings support further optimisation and clinical development of
Lara Šošić   +13 more
wiley   +1 more source

Component-resolved evaluation of the content of major allergens in therapeutic extracts for specific immunotherapy of honeybee venom allergy

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Allergen-specific immunotherapy is the only curative treatment of honeybee venom (HBV) allergy, which is able to protect against further anaphylactic sting reactions.
Simon Blank   +10 more
doaj   +1 more source

Distinct Gene Expression Profiles of Ara h 2‐Specific B Cells in Desensitization and Tolerance During Peanut Oral Immunotherapy

open access: yesAllergy, EarlyView.
Gene expression of Ara h 2‐specific B cells over the course of the peanut OIT. Isotype of allergen‐specific B cells changes through OIT towards IgG4. Peanut OIT changes the gene expression of allergen‐specific memory B cells. OIT patients showed increased gene expression for regulatory B cells and immune regulation.
Stephan R. Schneider   +48 more
wiley   +1 more source

Oligoclonal analysis of the atopic T cell response to the group 1 allergen of Cynodon dactylon (Bermuda grass) pollen: pre- and post-allergen-specific immunotherapy

open access: yes, 2002
Background: Bermuda grass pollen (BGP) is an increasingly important seasonal aeroallergen in Australia and other subtropical and temperate regions. BGP shares minimal allergenic cross-reactivity with pollens of rye grass or other Pooideae grasses often ...
NP Eusebius (14530337)   +6 more
core  

Medication with antihistamines impairs allergen-specific immunotherapy in mice

open access: yes, 2008
BACKGROUND: Histamine released from activated mast cells and basophils is an important mediator in allergy. Therefore, antihistamines are efficiently and widely used to suppress allergic symptoms.
Johansen, P; https://orcid.org/   +7 more
core   +1 more source

Influence of Environmental Pollution on Basophil Reactivity to Birch Pollen Allergens in Atopic and Non‐Atopic Subjects

open access: yesAllergy, EarlyView.
Birch pollen and PM10 are key determinants of clinical symptoms, particularly in asthma. Allergic people react stronger to the pollen collected in the highly polluted area than in the less polluted areas. When evaluating the effectiveness of allergen immunotherapy, it is essential to consider not only pollen concentrations but also levels of air ...
Maria Czarnobilska   +5 more
wiley   +1 more source

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