Results 21 to 30 of about 13,427 (242)

Allergen-specific immunotherapy in the treatment of bronchial asthma in children

Zdorovʹe Rebenka, 2019
The article presents a review of the literature that analyses the current possibilities and benefits of allergen-specific immunotherapy in children with bronchial asthma. Bronchial asthma has a leading place in the structure of allergic pathology.
L.V. Besh, Z.L. Slyuzar
doaj   +1 more source

Allergen Specific Immunotherapy (AIT)

World Journal of Advanced Research and Reviews, 2023
Allergic/atopic patients do not develop immune tolerance to certain substances in the environment which are harmless to non-allergic individuals. These patients are hypersensitive to these substances-allergens. Specific Allergen Immunotherapy (AIT), also known as Allergy Shots or Desensitization, is a therapeutic approach used to treat allergic ...
Thiago Luiz Bandeira, Isabela Mansur Bandeira, Juliana CM Vasconcellos, Ana Maria E. Dias dos Santos, Nilse Andréia Marcos Manuel, Paula Pessanha Silva Mitre, Camila Marques Rebello, Bruno de Brito Braga, Aderbal Sabrá-Filho, Selma Sabrá, Aderbal Sabrá, Luiz Werber-Bandeira   +11 more
openaire   +1 more source

Local side effects during sublingual allergen-specific immunotherapy and pathogenetically based methods for their correction (Review)

Аллергология и Иммунология в Педиатрии
Introduction. The study of the effectiveness and safety of allergen-specific immunotherapy remains relevant due to the emergence of a personalized approach in allergology and new dosage forms.
V. Ya. Zakurskaya
doaj   +1 more source

Allergen Specific Immunotherapy

Güncel Pediatri, 2015
Allergen specific immunotherapy (SIT) is the only treatment that can provide a cure for allergic disorders. This treatment is based on development of immune tolerance by exposure to allergen in repetitive and increasing doses. It is tertiary to avoidance of allergen and pharmacotherapy.
ÇEKİÇ, ŞÜKRÜ, SAPAN, NİHAT
openaire   +4 more sources

Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery

Advanced Science, EarlyView.
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra, Ibrahim M. Sayed, Souhrid Mukherjee, Honit Piplani, Aida Habtezion, Michael J. Rosen, Jospeh C. Wu   +6 more
wiley   +1 more source

ALLERGEN-SPECIFIC IMMUNOTHERAPY IN CHILDREN WITH POLLINOSIS

Вопросы современной педиатрии, 2014
Aim: to compare clinical efficacy and safety of sublingual and parenteral allergen-specific immunotherapy in children with pollinosis. Patients and methods: 143 patients with pollinosis aged from 5 to 16 years old were included into the study.
R. M. Torshkhoeva, L. S. Namazova-Baranova, O. I. Muradova, A. Yu. Tomilova, N. I. Voznesenskaya   +4 more
doaj   +1 more source

Local Specific IgE Levels Can Predict and Monitor the Therapeutic Response to Subcutaneous Immunotherapy With House Dust Mite

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Identifying predictive and monitoring biomarkers for allergen immunotherapy response is crucial for enhancing clinical efficacy. This study aims to investigate the systemic and local levels of immunoglobulins and identify potential biomarkers in house dust mite (HDM) allergic rhinitis (AR) patients who are undergoing subcutaneous ...
Xu Xu, Jingyun Li, Xu Zhang, Yu Song, Lin Xi, Luo Zhang, Yuan Zhang   +6 more
wiley   +1 more source

Establishment of enzyme-linked immunosorbent facilitated antigen binding as a biomarker assay for Japanese cedar pollen allergy immunotherapy

Journal of Pharmacological Sciences, 2019
Background: Clinical efficacy of allergen-specific Immunotherapy (AIT) towards Japanese cedar (JC) pollen allergy is firmly established but JC pollen-specific biomarker assays are lacking.
Chiharu Fukano, Katsuyo Ohashi-Doi, Kaare Lund, Atsuhito Nakao, Keisuke Masuyama, Tomokazu Matsuoka   +5 more
doaj   +1 more source

Allergen-Specific Immunotherapy With Liposome Containing CpG-ODN in Murine Model of Asthma Relies on MyD88 Signaling in Dendritic Cells

Frontiers in Immunology, 2020
Changing the immune responses to allergens is the cornerstone of allergen immunotherapy. Allergen-specific immunotherapy that consists of repeated administration of increasing doses of allergen extract is potentially curative. The major inconveniences of
Ricardo Wesley Alberca-Custodio, Lucas D. Faustino, Eliane Gomes, Fernanda Peixoto Barbosa Nunes, Mirian Krystel de Siqueira, Alexis Labrada, Rafael Ribeiro Almeida, Niels Olsen Saraiva Câmara, Denise Morais da Fonseca, Momtchilo Russo   +9 more
doaj   +1 more source

Rationale of New Grading System: Central Compartment Atopic Disease

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Central compartment atopic disease (CCAD) has recently been recognized as a distinct phenotype within the spectrum of type 2–dominant chronic rhinosinusitis (CRS). Although international guidelines highlight polypoid changes in the central nasal cavity, standardized diagnostic and classification criteria are still lacking.
Ramón Moreno‐Luna, Carmen Palma‐Martínez, Serafin Sánchez‐Gómez, Isam Alobid, Daniel Martin‐Jimenez, José Miguel Villacampa‐Aubá, Christian Calvo‐Henríquez, Alfonso Del Cuvillo, Alfonso Santamaría‐Gadea, Jaime González‐García, Richard J. Harvey, John M. DelGaudio   +11 more
wiley   +1 more source