Results 101 to 110 of about 254,825 (362)

Verekitug, a Novel Antibody Antagonist to the TSLP Receptor in Adults with Asthma: A 32‐Week Randomized Phase 1b Multiple Ascending‐Dose Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Verekitug, a novel, high‐affinity, fully human monoclonal antibody targeting thymic stromal lymphopoietin receptor (TSLPR), is in development as a potential treatment for severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and chronic obstructive pulmonary disease (COPD).
Dave Singh   +9 more
wiley   +1 more source

Pollen grains induce a rapid and biphasic eczematous immune response in atopic eczema patients [PDF]

open access: yes, 2008
Introduction: Eczematous reactions to type I allergy-inducing antigens are documented in a subgroup of patients with atopic eczema. Yet, the underlying immunological mechanisms are not well understood.
Behrendt, Heidrun   +7 more
core   +2 more sources

RORγt‐APCs: The New Masters of Oral Tolerance

open access: yesBarrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Effect of improved home ventilation on asthma control and house dust mite allergen levels [PDF]

open access: yes, 2009
The warm, humid environment in modern homes favours the dust mite population, but the effect of improved home ventilation on asthma control has not been established.
Ahlstedt   +27 more
core   +1 more source

Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl   +14 more
wiley   +1 more source

Epidemiologic study on the factors affecting the incidence of asthma and allergy with emphasis on arthropod allergens in patients referring to Imam Reza Clinic of Asthma and Allergy in Shiraz, 2016 [PDF]

open access: yesمجله علمی دانشگاه علوم پزشکی کردستان, 2019
Background and Aim: Asthma and allergy caused by arthropods are among the most common disorders which affect millions of people around the world. Among these diseases, respiratory allergic diseases and inhaled allergens are of particular importance. In
Shahriari-Namadi M   +3 more
doaj  

Anaphylaxis and Biphasic Phase in Thailand: 4-year Observation

open access: yesAllergology International, 2011
Background: Anaphylaxis, a severe systemic allergic reaction, can be fatal. However, its prevalence has been underestimated especially in biphasic phase, due to a lack of case awareness.
Ratchaya Lertnawapan   +1 more
doaj   +1 more source

Chitosan‐Based pH‐Responsive Films and Edible Coatings to Enhance Fruit Shelf‐Life: Impact of Plant Biomolecules and Composition

open access: yesFood Chemistry International, EarlyView.
Chitosan based coatings/films forming solution with the use ofplant extracts and parameters for fruit shelf life analysis. ABSTRACT Fresh fruits are a natural source of various minerals and vitamins, which are essential for human health. However, a rapid rate of respiration, water loss and fast ripening ability result in shorter shelf life and ...
Arun K. Singh
wiley   +1 more source

Molecular and immunological characterization of profilin from mugwort pollen [PDF]

open access: yes, 2002
In late summer in Europe, pollen of mugwort is one of the major sources of atopic allergens. No information about the complete molecular structure of any mugwort allergen has been published so far.
Aalbers, M.   +9 more
core   +2 more sources

Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review

open access: yesFood Frontiers, EarlyView.
Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv   +5 more
wiley   +1 more source

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