Results 101 to 110 of about 251,522 (310)

Innovative Drugs Approved in China After Registration Classification Reform: Current Status, Disparities, and Challenges

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Since 2016, the China National Medical Products Administration (NMPA) has reformed its drug registration classification rules and defines the innovative drugs as new drugs that have not been marketed domestically and overseas. This study sought to systematically evaluate the characteristics of the innovative drugs approved in China. The cross‐sectional
Xingyue Zhu, Die Xiao
wiley   +1 more source

Allergy Training or Lack Thereof [PDF]

open access: yes, 2018
Food allergies affect many people in our society today, and the food service industry must keep up with the demand for allergen-free food from their customers.
Freeman, Madelyn, Klenke, Mary Kate
core   +2 more sources

Protein Ingredients Control in Gluten Free Products Using SDS-PAGE, Developed Competitive Enzyme Immunoassays and Commercial ELISA Kits. [PDF]

open access: yes, 2018
Some protein ingredients declared in the label of gluten free products are allergenic proteins (milk, soy and egg).The proper identification of these proteins in food products is important for consumers who have food allergies.
Cagnasso, Carolina Elisa   +6 more
core   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

open access: yesBarrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Immune factors preceding diagnosis of glioma: a Prostate Lung Colorectal Ovarian Cancer Screening Trial nested case-control study. [PDF]

open access: yes, 2019
BackgroundEpidemiological studies of adult glioma have identified genetic and environmental risk factors, but much remains unclear. The aim of the current study was to evaluate anthropometric, disease-related, and prediagnostic immune-related factors for
Bracci, Paige M   +8 more
core  

Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model

open access: yesBarrier Immunity, EarlyView.
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia   +4 more
wiley   +1 more source

Lactobacillus gasseri suppresses Th17 pro-inflammatory response and attenuates allergen-induced airway inflammation in a mouse model of allergic asthma [PDF]

open access: bronze, 2011
Ren-Long Jan   +7 more
openalex   +1 more source

Cost‐effectiveness of subcutaneous immunotherapy for house dust mite‐induced allergic rhinitis in China

open access: yesEye &ENT Research, EarlyView.
Immunotherapy for allergic rhinitis: Higher initial costs offset by long‐term savings. Abstract Background Limited cost‐effectiveness studies have evaluated the long‐term efficacy of subcutaneous immunotherapy (SCIT). Objective This study's objective was to analyze the cost‐effectiveness of house dust mite‐specific SCIT (HDM‐SCIT), including post‐SCIT ...
Lei Ren, Lin Xi, Yuan Zhang, Luo Zhang
wiley   +1 more source

The Indoor Level of House Dust Mite Allergen Is Associated with Severity of Atopic Dermatitis in Children [PDF]

open access: gold, 2013
Jihyun Kim   +11 more
openalex   +1 more source

Inflammation and genetics in myo‐pericardial diseases: Insights from the Italian Study Group on Cardiomyopathies and Pericardial Diseases

open access: yesESC Heart Failure, EarlyView.
Proposed management of myo‐pericardial diseases. A systematic interdisciplinary approach to myo‐pericardial disease is essential to reach a correct diagnosis, starting from multiparametric characterization including EKG, echocardiography with GLS, laboratory exams and CMR or, in case of electric or haemodynamic instability, EMB.
Marco Merlo   +18 more
wiley   +1 more source

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