Results 101 to 110 of about 86,773 (215)

Bioinformatics‐Driven Design and Evaluation of Recombinant Multi‐Epitope Immunogens Derived From Snake Venom Toxins as Potential Antivenom Candidates

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Snakebite envenomation is a major public health concern, particularly in low‐ and middle‐income regions where access to safe and effective antivenoms is limited. Traditional antivenoms, derived from immunization with crude venom, often trigger adverse reactions and lack specificity against key venom components.
Hanan Maoz, Amir Elalouf
wiley   +1 more source

A Perspective on the Challenges and Issues in Developing Biomarkers for Human Allergic Risk Assessments [PDF]

, 2017
Godar, Dianne E., Merrill, Stephen, Mu, Ying   +2 more
core   +2 more sources

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Anti‐Allergic Potential of Chamaecrista nomame and Its Compound Luteolin for Novel Asthma Therapy

Phytotherapy Research, EarlyView.
Chamaecrista nomame (CN) and its active compound luteolin attenuate allergic airway inflammation by inhibiting mast cell activation and suppressing NF‐κB/MAPK signaling, leading to reduced cytokine production and OVA‐specific IgE levels. ABSTRACT Asthma is a chronic inflammatory disease driven by dysregulated immune responses and mast cell activation ...
Tae Kyeom Kang, Myungsuk Kim, Tam Thi Le, Geon Park, Yuna Jung, Hyobin Jeong, Youngsang Yoo, Wook‐Bin Lee, Sang Hoon Jung   +8 more
wiley   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

The evolving role of regulatory T cells in Sjögren's disease pathogenesis and the promise of Treg‐based therapies: A comprehensive review

Rheumatology &Autoimmunity, EarlyView.
Graphical Abstract The evolving role of regulatory T cells in primary Sjögren's disease pathogenesis and the promise of Treg‐based therapies. Abstract Sjögren's disease (SjD) is a chronic systemic autoimmune disorder characterised by exocrine gland dysfunction and diverse systemic manifestations.
Gagan Urs, Bharath Raj Srinivasan, Himabindu Jayaprakash Narayan, Mirunalini Gobinath, Lekitha Manjunath, Mahabaleshwar Mamadapur   +5 more
wiley   +1 more source

Strategic Design of Public Food Procurement to Leverage Positive Food Systems Outcomes: A Framework of Actions

Sustainable Development, EarlyView.
ABSTRACT There is substantial potential for the procurement of food by public institutions to contribute to Sustainable Development across multiple environmental, social, and economic outcomes. In this study we used theories of policy instrumentation and learning to analyse global guidance for designing public food procurement instruments to leverage ...
Erica Reeve, Carolina Venegas Hargous, Penny Farrell, Dori Patay, Holly Rippin, Anna Roesler, Anna Peeters, Anne Marie Thow   +7 more
wiley   +1 more source

Leveraging the Potential of Public Food Procurement to Achieve Multiple Food System Outcomes: Insights From a Policy Analysis in Australia

Sustainable Development, EarlyView.
ABSTRACT Government food procurement investment offers significant potential to advance health and sustainability goals; yet, integrating these dimensions into policy design has proved challenging. We mapped and analysed 38 food procurement and catering‐specific policies in Australia to identify ways to strengthen policy design: 20 governing ...
Carolina Venegas Hargous, Anne Marie Thow, Belinda Reeve, Erica Reeve   +3 more
wiley   +1 more source

Early‐Life Nutritional Supplements, Household Environments, and Air Pollution Associated With Children's Helicobacter pylori Infection: A Chinese Multicenter Mother‐Child Study

Safety Science and Technology, EarlyView.
Early‐life intake of nutritional additives, particularly during pregnancy and the early postnatal period, reduces the risk of Helicobacter pylori infection (HPI) in children by enhancing immune function and preventing gastrointestinal infections through proper nutrition, supporting the “(Pre‐)Fetal origins of HPI” hypothesis through the “gut–uterine ...
Chan Lu, Yufang Shan, Yuanqi Li, Wen Deng, Yuqing Chen, Yao Chen   +5 more
wiley   +1 more source

Clinical characteristics of immediate allergic adverse reactions to intravenous amoxicillin‒clavulanic acid in conscious dogs

Veterinary Record, EarlyView.
Abstract Background Amoxicillin‒clavulanic acid (AMC) is one of the most frequently used antibiotics in small animal practice, and reports on adverse reactions are scarce. The aim of this study was to describe the clinical characteristics of immediate allergic adverse reactions to intravenous (IV) AMC in conscious dogs. Methods The medical records of a
Leonel Frutuoso, Anna Threlfall
wiley   +1 more source