Results 121 to 130 of about 120,561 (245)

Ozone Inhalation Attenuated the Effects of Budesonide on Aspergillus fumigatus-Induced Airway Inflammation and Hyperreactivity in Mice. [PDF]

open access: yes, 2019
Inhaled glucocorticoids form the mainstay of asthma treatment because of their anti-inflammatory effects in the lung. Exposure to the air pollutant ozone (O3) exacerbates chronic airways disease.
Flayer, Cameron H   +6 more
core  

Allergic Contact Dermatitis: A Comparative Study of Elderly and Young Over Time

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Delayed hypersensitivity reactions, such as allergic contact dermatitis (ACD), present distinct patterns across age groups. While age‐related immune changes are well‐documented, their impact on patch test outcomes and allergen sensitization in elderly individuals remains underexplored.
Roberto Mazzetto   +5 more
wiley   +1 more source

Accommodating the Allergic Employee in the Workplace [PDF]

open access: yes, 1994
[Excerpt] Once an employer learns an applicant or employee is allergic, and in need of an accommodation, the employer may be required by the Americans with Disabilities Act to provide the needed accommodation.
Brown, Nellie J
core   +1 more source

Oral Administration of Trichosanthes Kirilowii Fruit Extract Ameliorates Airway Inflammation and Suppresses Th2 Cell Activities in Ovalbumin‐Sensitized Mice

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Trichosanthes kirilowii is a plant used in traditional Chinese medicine. Its fruits, seeds, and roots can all be used medicinally. The fruit of T. kirilowii has a moistening effect on the lung for arresting cough. However, there is no scientific research to prove that the fruit of T. kirilowii can improve asthma. Herein, we evaluated whether T.
Ting‐Chi Lin   +6 more
wiley   +1 more source

GNPAT/USP30 Stabilizes DRP1 Protein to Promote Mitochondrial Fission and Functional Damage in COPD Progression

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Our previous study revealed the role of glycerol phosphate O‐acyltransferase (GNPAT) in regulating chronic obstructive pulmonary disease (COPD). However, its further mechanisms remained unclear. In this study, COPD models were established by exposing mice to cigarette smoke particulates.
Xin‐Gui Cheng   +5 more
wiley   +1 more source

Factors Affecting Nasal Discharge in Chronic Rhinosinusitis Patients

open access: yesThe Laryngoscope, EarlyView.
This study aimed to identify patient‐specific factors influencing the severity of nasal drainage in chronic rhinosinusitis (CRS) patients. It found that postnasal discharge (PND) was the most severe symptom, with female gender, CRS without nasal polyps, prior endoscopic sinus surgery, and allergies significantly associated with severe PND.
Pranav A. Patel   +7 more
wiley   +1 more source

Feasibility of Treating Eosinophilic Chronic Rhinosinusitis Using Short‐Chain Fatty Acids

open access: yesThe Laryngoscope, EarlyView.
Epithelial cell‐derived cytokines including thymic stromal lymphopoietin (TSLP) are important in the pathogenesis of chronic rhinosinusitis with nasal polyps. We demonstrate the inhibitory effect of TSLP production in airway epithelial cells and eosinophil survival by short‐chain fatty acids (SCFAs) as a potential new strategy to reduce nasal polyps ...
Rikako Gozawa   +12 more
wiley   +1 more source

Tumor Necrosis Factor‐α Induces Human Bronchial Fibroblasts to Produce Cytokines: Implications for Airway Inflammation

open access: yesMed Research, EarlyView.
ABSTRACT Pulmonary fibroblasts coordinate the progression of airway inflammation through multiple pathways. However, the role and underlying mechanisms of its subtype, bronchial fibroblasts, under TNF‐α induction remain unclear. This study found that TNF‐α was highly expressed in the airway with asthma patients.
Dong Zhang   +7 more
wiley   +1 more source

Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy