Results 221 to 230 of about 135,884 (265)

Standardized allergen extracts for allergen immunotherapy

Allergy and Asthma Proceedings, 2022
Nineteen U.S. allergen extracts were standardized by the U.S. Food and Drug Administration (FDA) between 1987 and 1998, including of two house-dust mites, short ragweed, cat hair and cat pelt, seven temperate and one southern grass, and six Hymenoptera venom preparations. Relevant literature was reviewed.
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Updates on Databases of Allergens and Allergen-Epitopes

2023
The increasing prevalence of allergic diseases is of great public health concern. Environmental and food allergens are the major triggers of allergic diseases via respiratory or gastrointestinal routes, respectively. A major setback in the clinical management of allergies is the unavailability of purified allergens required for diagnostic purposes ...
Rajat Kanti, Sarkar, Nandini, Ghosh, Gaurab, Sircar, Sudipto, Saha   +3 more
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Cockroach Allergens: Function, Structure and Allergenicity

Protein & Peptide Letters, 2007
Cockroach allergy is a widespread health problem in the world, associated with the development of asthma. The German and American cockroach species are important producers of a wide variety of allergens. Knowledge of their structure and function contributes to understand their role in allergy and to design tools for diagnosis and immunotherapy.
A, Pomés, S, Wünschmann, J, Hindley, L D, Vailes, M D, Chapman   +4 more
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Allergenic characteristics of a modified peanut allergen

Molecular Nutrition & Food Research, 2005
Attempts to treat peanut allergy using traditional methods of allergen desensitization are accompanied by a high risk of anaphylaxis. The aim of this study was to determine if modifications to the IgE-binding epitopes of a major peanut allergen would result in a safer immunotherapeutic agent for the treatment of peanut-allergic patients.
Nina, King, Ricki, Helm, J Steven, Stanley, Stefan, Vieths, Dirk, Lüttkopf, Lina, Hatahet, Hugh, Sampson, Laurent, Pons, Wesley, Burks, Gary A, Bannon   +9 more
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Allergen immunotherapy with cat allergen peptides

Springer Seminars in Immunopathology, 2004
Desensitising therapy for allergic diseases has changed little over almost a century of practice. Administration of increasing doses of extracts of allergen source material has been shown to be reproducibly effective when patients are carefully selected and appropriate concentrations of allergen employed.
A Barry, Kay, Mark, Larché
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Allergens and Allergen Immunotherapy

2020
Basics Allergen Immunotherapy in a Historical Perspective David Fitzhugh, Sheldon G. Cohen, and Richard Evans III (deceased) Definition of an Allergen (Immunobiology) Malcolm N. Blumenthal and Lauren Fine Allergen Nomenclature Heimo Breiteneder and Martin D. Chapman Immunological Responses to Subcutaneous Allergen Immunotherapy Mohamed H.
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Allergen-Specific Immunotherapy with Recombinant Allergens

2011
Subcutaneous immunotherapy is a well-documented treatment of allergic rhinitis and asthma. The major limitation is the risk of anaphylactic side effects. The documentation of clinical efficacy is based on crude allergenic extracts sometimes containing varying amounts of individual allergens including allergens to which the patient may not be sensitized.
G, Pauli, Hans-Jørgen, Malling
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The advent of recombinant allergens and allergen cloning

Journal of Allergy and Clinical Immunology, 2011
When the allergen nomenclature system was adopted in 1986, allergens were identified by their behavior on electrophoresis and chromatography and by reactivity to shared antisera. Not only was this unsatisfactory for standardization, but the processes of allergic sensitization and immunotherapy could not be studied in the framework of antigen processing
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Determinants of allergenicity

Journal of Allergy and Clinical Immunology, 2009
The question "What makes an allergen an allergen?" has puzzled generations of researchers, and we still do not have a conclusive answer. Despite increasing knowledge about the molecular and functional characteristics of allergens that have been identified, we still do not fully understand why some proteins are clinically relevant allergens and most are
Traidl-Hoffmann, Claudia, Jakob, Thilo, Behrendt, Heidrun   +2 more
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Allergens and Allergen Immunotherapy

1998
Allergen immonotherapy in historical perpective definition of an allergen aerobiology allergen nomenclature tree pollen allergens grass pollen allergens weed pollen allergens mold allergens biting insect allergens mite allergens cockroach and other inhalent insect allergens food allergens latex allergens drug allergens, haptens and anaphylatoxins ...
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