Results 21 to 30 of about 255,557 (363)

Shh production and Gli signaling is activated in vivo in lung, enhancing the Th2 response during a murine model of allergic asthma [PDF]

open access: yes, 2017
The pathophysiology of allergic asthma is driven by T-helper 2 (Th2) immune responses following aeroallergen inhalation. The mechanisms that initiate, potentiate and regulate airways allergy are incompletely characterized.
Crompton, Tessa   +4 more
core   +3 more sources

Fungal allergens [PDF]

open access: yesClinical Microbiology Reviews, 1995
Airborne fungal spores occur widely and often in far greater concentrations than pollen grains. Immunoglobulin E-specific antigens (allergens) on airborne fungal spores induce type I hypersensitivity (allergic) respiratory reactions in sensitized atopic subjects, causing rhinitis and/or asthma.
W E, Horner   +3 more
openaire   +2 more sources

Japanese Society of Allergology task force report on standardization of house dust mite allergen vaccines – Secondary publication

open access: yesAllergology International, 2015
Background: In the 1990s, the Japanese Society of Allergology (JSA) standardized Japanese cedar pollen allergen vaccines. In the present study, the task force for house dust mite (HDM) allergen standardization of the Committee for Allergens and ...
Toshiro Takai   +8 more
doaj   +1 more source

Climate change, aeroallergens, and the aeroexposome

open access: yesEnvironmental Research Letters, 2021
Allergic diseases are a major public health problem globally and are increasing. The impacts of climate change on aeroallergens such as pollen and fungal spores and allergic respiratory diseases such as allergic asthma and allergic rhinitis have been ...
Paul J Beggs
doaj   +1 more source

Multigenerational Epigenetic Regulation of Allergic Diseases: Utilizing an Experimental Dust Mite-Induced Asthma Model

open access: yesFrontiers in Genetics, 2021
Environmental exposures have been linked to increased asthma risk, particularly during pregnancy and in early life. Here we use a mouse model of allergic lung disease to examine the effects of pre- and perinatal house dust mite (HDM) allergen exposure on
Jairus C. Pulczinski   +8 more
doaj   +1 more source

Applying the adverse outcome pathway (AOP) for food sensitization to support in vitro testing strategies [PDF]

open access: yes, 2019
Background Before introducing proteins from new or alternative dietary sources into the market, a compressive risk assessment including food allergic sensitization should be carried out in order to ensure their safety.
Benedé, Sara   +14 more
core   +1 more source

Regulation and directed inhibition of ECP production by human neutrophils

open access: yesFrontiers in Immunology, 2022
BackgroundNeutrophils are involved in the pathophysiology of allergic asthma, where the Eosinophil Cationic Protein (ECP) is a critical inflammatory mediator.
Antonio Vega-Rioja   +18 more
doaj   +1 more source

Pollen grains induce a rapid and biphasic eczematous immune response in atopic eczema patients [PDF]

open access: yes, 2008
Introduction: Eczematous reactions to type I allergy-inducing antigens are documented in a subgroup of patients with atopic eczema. Yet, the underlying immunological mechanisms are not well understood.
Behrendt, Heidrun   +7 more
core   +2 more sources

Cross-sensitization between poppy seed and buckwheat in a food-allergic patient with poppy seed anaphylaxis [PDF]

open access: yes, 2006
The opium poppy, Papaver somniferum L., is the source of both poppy seeds and opium. The commercially available seeds are widely used as ingredients for various kinds of food.
Oppel, T., Thomas, P., Wollenberg, A.
core   +1 more source

Preventing Atopic Diseases During Childhood – Early Exposure Matters

open access: yesFrontiers in Immunology, 2021
Atopic diseases in childhood are a major burden worldwide and there is still a lack of knowledge about treatable causes. In industrialized countries such as Germany, almost every second child is sensitized to at least one common allergen.
Mandy Pierau   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy