Results 31 to 40 of about 180,280 (304)

Allergen-Specific Immunotherapy With Liposome Containing CpG-ODN in Murine Model of Asthma Relies on MyD88 Signaling in Dendritic Cells

Frontiers in Immunology, 2020
Changing the immune responses to allergens is the cornerstone of allergen immunotherapy. Allergen-specific immunotherapy that consists of repeated administration of increasing doses of allergen extract is potentially curative. The major inconveniences of
Ricardo Wesley Alberca-Custodio, Lucas D. Faustino, Eliane Gomes, Fernanda Peixoto Barbosa Nunes, Mirian Krystel de Siqueira, Alexis Labrada, Rafael Ribeiro Almeida, Niels Olsen Saraiva Câmara, Denise Morais da Fonseca, Momtchilo Russo   +9 more
doaj   +1 more source

Spectrum of Allergens and Allergen Biology in India [PDF]

International Archives of Allergy and Immunology, 2018
The growing prevalence of allergy and asthma in India has become a major health concern with symptoms ranging from mild rhinitis to severe asthma and even life-threatening anaphylaxis. The “allergen repertoire” of this subcontinent is highly diverse due to the varied climate, flora, and food habits.
Kashinath, Bhattacharya, Gaurab, Sircar, Angira, Dasgupta, Swati, Gupta Bhattacharya   +3 more
openaire   +2 more sources

Allergen-Specific Antibodies Regulate Secondary Allergen-Specific Immune Responses

Frontiers in Immunology, 2019
Immunoglobulin E (IgE)-associated allergy is the most common immunologically-mediated hypersensensitivity disease. It is based on the production of IgE antibodies and T cell responses against per se innocuous antigens (i.e., allergens) and subsequent ...
Julia Eckl-Dorna, Sergio Villazala-Merino, Birgit Linhart, Alexander V. Karaulov, Yury Zhernov, Musa Khaitov, Verena Niederberger-Leppin, Rudolf Valenta, Rudolf Valenta, Rudolf Valenta   +9 more
doaj   +1 more source

Early inhalant allergen sensitization at component level: an analysis in atopic Dutch children

Frontiers in Allergy, 2023
BackgroundAllergic rhinitis is a common respiratory disease in children and sensitization to inhalant allergens plays a significant role in its development.
Lonneke J. Landzaat, Joyce A. M. Emons, Laura J. H. Sonneveld, Marco W. J. Schreurs, Nicolette J. T. Arends   +4 more
doaj   +1 more source

Molecular and immunological characterization of profilin from mugwort pollen [PDF]

, 2002
In late summer in Europe, pollen of mugwort is one of the major sources of atopic allergens. No information about the complete molecular structure of any mugwort allergen has been published so far.
Briza, P., Richter, K., Ebner, Christof, Willeroidee, Marika, Briza, Peter, van Ree, Ronald, Richter, Klaus, Willeroider, M., Aalbers, Marja, Wopfner, Nicole, Wopfner, N., Ferreira, F., Aalbers, M., Ebner, C., Thalhamer, Josef, Ferreira, Fatima, Hebenstreit, Daniel, Thalhamer, J., Ree, R. van   +18 more
core   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

BC02-adjuvanted varicella-zoster virus glycoprotein E subunit vaccine overcomes immunosenescence to induce robust neutralizing antibodies and multifunctional T-cell immunity in seropositive aged murine models

Human Vaccines & Immunotherapeutics
After infection with the varicella-zoster virus (VZV), the virus becomes latent in the sensory ganglia. Immune senescence may lead to its reactivation, resulting in herpes zoster (HZ). The limited immunogenicity of current vaccines in elderly populations
Junli Li, Xiaochi Li, Yang Yang, LiLi Fu, Weixin Du, Jiazheng Wei, Kexin Su, Cheng Su, Xiaobing Shen, Guozhi Wang, Aihua Zhao   +10 more
doaj   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Eosinophilic Pneumonia Triggered by Toxocara canis in a Patient with Primary Ciliary Dyskinesia: A Clinical Case Report

Medicina
Primary ciliary dyskinesia (PCD) is a rare genetic disorder that affects the structure and function of cilia, primarily impacting the respiratory system.
Kacper Packi, Wanda Fugiel, Violetta Gołąbek, Alicja Rudek, Agnieszka Śliwińska   +4 more
doaj   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source