Results 101 to 110 of about 211,796 (270)

Postcode‐Level Variation and Environmental Determinants of Respiratory Allergies in a Large German Cohort

open access: yesAllergy, EarlyView.
Young children (0–9 years) and residents of urban areas appeared particularly vulnerable to respiratory allergy development and exacerbation. Incidence showed nonlinear associations with PM10, PM2.5, temperature, and alder/birch pollen, while DPMR showed similar patterns, except for NO2 and the interaction O3*NO2.
Trang Dao‐Siebel   +6 more
wiley   +1 more source

Allergen Immunotherapy in Asthma: Current Status and Future Perspectives

open access: yesAllergology International, 2010
Allergen immunotherapy targets Th2 cells activated by specific allergens, which constitutes the basis of allergic disease. Therefore, this approach has therapeutic potential for a variety of allergic diseases, including asthma, and may modify their ...
Makoto Nagata, Kazuyuki Nakagome
doaj   +1 more source

Determinants of Poor Health‐Related Quality of Life in Patients With Food Allergy

open access: yesAllergy, EarlyView.
Machine‐learning analysis of 502 well‐characterised food‐allergic patients was used to identify key determinants of poor FA‐HRQL, defined as FAQLQ ≥ 5. The most relevant predictors were adult age, female sex, multiple food allergies, severe reactions, need for urgent care, onset before 18 years, and longer disease duration.
Rosialzira Natasha Vera‐Berrios   +24 more
wiley   +1 more source

EAACI: A European Declaration on Immunotherapy. Designing the future of allergen specific immunotherapy

open access: yesClinical and Translational Allergy, 2012
Allergy today is a public health concern of pandemic proportions, affecting more than 150 million people in Europe alone. In view of epidemiological trends, the European Academy of Allergy and Clinical Immunology (EAACI) predicts that within the next few
Calderon Moises A   +45 more
doaj   +1 more source

Surgical Management of Non‐Allergic Rhinitis—An EAACI Task Force Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT Non‐allergic rhinitis is a frequent yet underdiagnosed cause of chronic nasal symptoms, including nasal congestion, rhinorrhoea, and upper airway hyperreactivity. Its pathophysiology involves neurogenic dysregulation, leading to excessive mucus production and vasodilation.
Marie Lundberg   +18 more
wiley   +1 more source

Evaluation of Scoring Atopic Dermatitis (SCORAD) and scratching behavior in BALB/c mice treated with house dust mite immunotherapy

open access: yesVeterinary Integrative Sciences
Allergen specific immunotherapy controls the reaction and builds immunological tolerance by giving an allergen in escalating doses. Research on immunotherapy in atopic dermatitis (AD) mouse model offers a new perspective on the approach of ...
Sylvia Anggraeni   +3 more
doaj   +1 more source

Immunoglobulin G in IgE-mediated allergy and allergen-specific immunotherapy

open access: yes, 2014
Allergen-specific IgG antibodies play a significant role in allergen-specific tolerance, either naturally induced or generated by specific immunotherapy.
Hofmaier S, Comberiati P, Matricardi PM.
core  

Mechanisms of subcutaneous allergen immunotherapy

open access: yes, 2011
Allergen-specific immunotherapy (SIT) is the only curative approach in the treatment of allergic diseases defined up-to-date. Peripheral T-cell tolerance to allergens, the goal of successful allergen-SIT, is the primary mechanism in healthy immune ...
Akdis, C A   +5 more
core   +1 more source

Nematode in Cockroaches: A Potential Allergen Source

open access: yes
Allergy, EarlyView.
Dongjun Kang   +5 more
wiley   +1 more source

Dendritic Cell α‐Ketoglutarate Regulates Tfh Polarization in Allergy

open access: yesAllergy, EarlyView.
Allergen induces a dendritic cell metabolism shift toward glutaminolysis with α‐ketoglutarate as a regulator of Tfh subset polarization. Glutaminolysis is required for DC allergen uptake, co‐stimulatory molecule expression, and CLR expression. Modulation of glutaminolysis, JmjD3 histone demethylation, or HIF‐1α degradation alters Tfh polarization and ...
Anuj Tharakan   +16 more
wiley   +1 more source

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