Results 111 to 120 of about 188,190 (277)

Evaluation of Scoring Atopic Dermatitis (SCORAD) and scratching behavior in BALB/c mice treated with house dust mite immunotherapy

Veterinary Integrative Sciences
Allergen specific immunotherapy controls the reaction and builds immunological tolerance by giving an allergen in escalating doses. Research on immunotherapy in atopic dermatitis (AD) mouse model offers a new perspective on the approach of ...
Sylvia Anggraeni, Dinar Chieko Triesayuningtyas, Anang Endaryanto, Cita Rosita Sigit Prakoeswa   +3 more
doaj   +1 more source

Intranasal Immunotherapy Is More Effective Than Intradermal Immunotherapy for the Induction of Airway Allergen Tolerance in Th2-Sensitized Mice

, 2019
Immunotherapy (IT) by injection more readily induces clinical tolerance to stinging insects than to respiratory allergens. However, while systemic immunization induces adaptive responses systemically, the induction of mucosal immunity generally requires ...
Horner AA, Takabayashi K,, Zubeldia Ortuño, José Manuel, Libet L, Chisholm D,   +4 more
core   +1 more source

Classification of Seasonal Allergic Rhinitis Patients by Prospective Patient‐Recorded Symptoms: The @IT.2020 Project

Allergy, EarlyView.
Daily prospective symptom reports from participants in this multicentre observational study were compared to retrospective (last 12 months) reports based on ARIA clinical questionnaire. Retrospective reports substantially underestimated, and to a lesser extent overestimated, symptom frequency compared to e‐Diary prospective reports. Since retrospective
S. Dramburg, C. J. Hernandez Toro, U. Grittner, E. Potapova, A. Travaglini, S. Tripodi, S. Arasi, S. Pelosi, F. Monnati, A. Acar Şahin, X. Aggelidis, A. Barbalace, A. Bourgoin, B. Bregu, M. A. Brighetti, E. Caeiro, S. Caglayan Sozmen, L. Caminiti, D. Charpin, M. Couto, L. Delgado, A. Di Rienzo Businco, C. Dimier, M. V. Dimou, J. A. Fonseca, O. Goksel, D. Hernandez, T. M. Hoffmann, D. T. Jang, F. Kalpaklioglu, B. Lame, R. Llusar, M. Makris, A. Mazon, E. Mesonjesi, A. Nieto, A. B. Öztürk, L. Pahus, G. Pajno, I. Panasiti, N. G. Papadopoulos, E. Pellegrini, A. M. Pereira, M. Pereira, N. M. Pinar, A. Priftanji, F. Psarros, C. Sackesen, I. Sfika, J. Suarez, M. Thibaudon, U. Uguz, V. Verdier, V. Villella, P. Xepapadaki, D. Yazici, P. M. Matricardi   +56 more
wiley   +1 more source

Update on mechanisms of allergen injection immunotherapy

, 2008
The incidence of allergic diseases is increasing at an alarming rate, paricularly in countries with a western lifestyle. Currently in the UK, approximately one quarter of the population suffers from seasonal allergic rhinitis.
Durham, S. R., James, Louisa Katherine
core   +1 more source

Skin Abnormalities at Checkpoint Inhibitor Therapy Initiation Are Associated With Skin Rash Development in Oncology Patients

Allergy, EarlyView.
Skin tape strip lipidomic analysis revealed preexisting skin barrier lipid abnormalities at day 0 that were further exacerbated after 6 weeks of CPI treatment. Significant changes in skin (but not plasma) proinflammatory cytokines were identified in future ircAE patients after 6 weeks of CPI immunotherapy.
Taras Lyubchenko, Evgeny Berdyshev, Ryan M. Weight, Olivia Xiao, Neil J. Shah, Alina Markova, Mario E. Lacouture, Jeffrey A. Kern, Elena Goleva, Donald Y. M. Leung   +9 more
wiley   +1 more source

Basophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test

Allergy, EarlyView.
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan, Sofia Vlasova, Alicia Chenoweth, Debra H. Josephs, Heather J. Bax, Sophia N. Karagiannis   +5 more
wiley   +1 more source

Three‐Year Post‐Treatment Outcomes Following Cessation of Peanut Oral Immunotherapy: Comparisons by Clinical Allergy Status and Treatment Group

Allergy, EarlyView.
Paxton Loke, Xiaofang Wang, Sophie Rosser, Melanie Lloyd, Sarah E. Ashley, Adriana C. Lozinsky, Julie Burns, Patrick Quinn, Michael D. O'Sullivan, Michael Gold, Francesca Orsini, Mimi L. K. Tang   +11 more
wiley   +1 more source

Efficacy and Safety of Intralymphatic Immunotherapy With Grass Allergoid and Microcrystalline Tyrosine: A Double‐Blind Randomised Placebo‐Controlled Trial

Allergy, EarlyView.
This is the first randomised placebo‐controlled trial of intralymphatic immunotherapy using a microcrystalline tyrosine‐adjuvanted grass pollen allergoid. Three ultrasound‐guided ILIT injections were well tolerated and reduced combined symptom‐medication scores compared with placebo. The findings support further optimisation and clinical development of
Lara Šošić, Stephan C. Flory, Claudia C. V. Lang, Emma C. Widmer, Alexandra Chabot, Johannes M. Schmid, Tobias Andermatt, David Melillo, Bjarke Hviid‐Vyff, Maibritt Mardahl, Peter Schmid‐Grendelmeier, Thomas M. Kündig, Hans Jürgen Hoffmann, Pål Johansen   +13 more
wiley   +1 more source

Distinct Gene Expression Profiles of Ara h 2‐Specific B Cells in Desensitization and Tolerance During Peanut Oral Immunotherapy

Allergy, EarlyView.
Gene expression of Ara h 2‐specific B cells over the course of the peanut OIT. Isotype of allergen‐specific B cells changes through OIT towards IgG4. Peanut OIT changes the gene expression of allergen‐specific memory B cells. OIT patients showed increased gene expression for regulatory B cells and immune regulation.
Stephan R. Schneider, Juan‐Felipe López, Huseyn Babayev, Willem van de Veen, Minglin Yang, Cezmi A. Akdis, Kari Nadeau, Carolyn H. Baloh, Stacie M. Jones, Lisa M. Wheatley, Mübeccel Akdis, IMPACT, Amy M. Scurlock, D. Pesek, Joy Laurienzo‐Panza, Marshall Plaut, A. Wesley Burks, Edwin H. Kim, Mike Kulis, Anna Nowak‐Wegrzyn, Hugh A. Sampson, Julie Wang, Robert A. Wood, Sharon Chinthrajah, Robert Sayantani B. Sindher, Jacqueline Johnson, Katharine Spain, Denise C. Babineau, Hyunsook Chin, Rachel Yan, Don Whitehouse, Michelle L. Sever, Srinath Sanda, David Larson, Tielin Qin, Gina Marchesini, Kavitha Gilroy, Sylvia Posso, Sabrina Skiba, Thien‐Son Nguyen, Adam Wojno, Tuan Nguyen, Vivian Gersuk, Quynh‐Anh Nguyen, Jessica Garber, Kimberly O'Brien, Brandon Larson, C. Cousens‐Jacobs, Alex Hu   +48 more
wiley   +1 more source

Transition between subcutaneous and sublingual allergen immunotherapy: Recommendations of the Brazilian Association of Allergy and Immunology (ASBAI)

Journal of Allergy and Clinical Immunology: Global
The use of allergen immunotherapy (AIT) in Brazil has specific regional conditions owing to the pattern of allergen sensitization, as well as to genetic, socioeconomic, and cultural characteristics.
Fernando Monteiro Aarestrup, MD, PhD, Ernesto Akio Taketomi, MD, PhD, Clóvis Eduardo Santos Galvão, MD, PhD, Gil Bardini Alves, MD, MSc, Geórgia Véras de Araújo Gueiros Lira, MD, PhD, Marcos Reis Gonçalves, MD, MSc, Mariana Graça Couto Miziara, MD, Sidney Souteban Maranhão Casado, MD, Veridiana Aun Rufino Pereira, MD, PhD, Dirceu Solé, MD, PhD, Ekaterini Simoes Goudouris, MD, PhD, Fabio Chigres Kuschnir, MD, PhD   +11 more
doaj   +1 more source