Results 111 to 120 of about 211,796 (270)
Inhibition of allergen-IgE binding to B cells by IgG antibodies after grass pollen immunotherapy
, 2003 BackgroundAmong atopic individuals, levels of allergen-specific IgG antibodies have been inversely associated with the degree of allergen sensitization.Petra A Wachholz, Durham, Stephen R, Nanna Kristensen Soni, Stephen R Durham, Till, Stephen J; id_orcid, Soni, Nanna Kristensen, Wachholz, Petra A, Stephen J Till +7 morecore +1 more sourceAllergen immunotherapy in dogs [PDF]
, 2020 The article presents current knowledge about allergen immunotherapy (AIT), in dogs, including the mechanism of action, indications, protocols used and efficacy of this treatment option.Trojakowska, Anna, Piecuch, Aleksandracore Route of Allergen Immunotherapy: A Global Look Into Physicians' Motivations
Allergy, EarlyView.Little is known about the factors driving AIT prescription in clinical practice, including the level of personalization from patient to patient. Patient‐centred factors theoretically would favour SLIT prescription. Doctors’ knowledge, training, and country influence the final decision on the route.Carmen Vidal, Davide P. Caimmi, Pablo Rodriguez del Rio, Óscar Lado‐Baleato, Francisco Gude, Pilar Rico‐Nieto, Thomas B. Casale, Jorge A. Aguilar, Maryam Ali Al‐Nesf, Fatima Ashkanani, Adeeb Bulkhi, Juan C. Cardet, Claudia Almendarez, Silvia Caimmi, Iván Cherrez, Enza D’Auria, Stephanie Dramburg, Motohiro Ebisawa, Naoko Fusayasu, Maximiliano Gomez, Sandra Gonzalez‐Diaz, Carla Irani, Andrey Kamaev, Connie Katelaris, Narinder Kaur, Oksana KurBacheva, José I. Larco, Désirée Larenas‐Linnemann, Margaret Li, Olga Patricia Monge‐Ortega, Pablo Moreno, Oliver Pfaar, Cesar F. Pozo‐Beltrán, Marta E. Rubio, Jorge Sanchez, Giovanni Sedo, Silvia Uriarte, Lin Yang, Hao Chen, Rongfei Zhu, Pascal Demoly, Moises A. Calderon, on behalf of the CHOICE‐Global Survey Team +42 morewiley +1 more sourceClassification of Seasonal Allergic Rhinitis Patients by Prospective Patient‐Recorded Symptoms: The @IT.2020 Project
Allergy, EarlyView.Daily prospective symptom reports from participants in this multicentre observational study were compared to retrospective (last 12 months) reports based on ARIA clinical questionnaire. Retrospective reports substantially underestimated, and to a lesser extent overestimated, symptom frequency compared to e‐Diary prospective reports. Since retrospective Stephanie Dramburg, Camilo J. Hernandez Toro, Ulrike Grittner, Ekaterina Potapova, Alessandro Travaglini, Salvatore Tripodi, Stefania Arasi, Simone Pelosi, Francesco Monnati, Aydan Acar Şahin, Xenophon Aggelidis, Andrea Barbalace, Anne Bourgoin, Blerina Bregu, Maria Antonia Brighetti, Elsa Caeiro, Sule Caglayan Sozmen, Lucia Caminiti, Denis Charpin, Mariana Couto, Luís Delgado, Andrea Di Rienzo Businco, Claire Dimier, Maria V. Dimou, João A. Fonseca, Ozlem Goksel, Dolores Hernandez, Tara Maria Hoffmann, Dah Tay Jang, Fusun Kalpaklioglu, Blerta Lame, Ruth Llusar, Michael P. Makris, Angel Mazon, Eris Mesonjesi, Antonio Nieto, Ayse Bilge Öztürk, Laurie Pahus, Giovanni Battista Pajno, Ilenia Panasiti, Nikolaos G. Papadopoulos, Elisabetta Pellegrini, Ana Margarida Pereira, Mariana Pereira, Munevver Pinar, Alfred Priftanji, Fotis Psarros, Cansin Sackesen, Ifigenia Sfika, Javier Suarez, Michel Thibaudon, Ulas Uguz, Valentine Verdier, Valeria Villella, Paraskevi Xepapadaki, Duygu Yazici, Paolo M. Matricardi +56 morewiley +1 more sourceSkin Abnormalities at Checkpoint Inhibitor Therapy Initiation Are Associated With Skin Rash Development in Oncology Patients
Allergy, EarlyView.Skin tape strip lipidomic analysis revealed preexisting skin barrier lipid abnormalities at day 0 that were further exacerbated after 6 weeks of CPI treatment. Significant changes in skin (but not plasma) proinflammatory cytokines were identified in future ircAE patients after 6 weeks of CPI immunotherapy.Taras Lyubchenko, Evgeny Berdyshev, Ryan M. Weight, Olivia Xiao, Neil J. Shah, Alina Markova, Mario E. Lacouture, Jeffrey A. Kern, Elena Goleva, Donald Y. M. Leung +9 morewiley +1 more sourceBasophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test
Allergy, EarlyView.ABSTRACT
Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.Jitesh Chauhan, Sofia Vlasova, Alicia Chenoweth, Debra H. Josephs, Heather J. Bax, Sophia N. Karagiannis +5 morewiley +1 more sourceEfficacy and Safety of Intralymphatic Immunotherapy With Grass Allergoid and Microcrystalline Tyrosine: A Double‐Blind Randomised Placebo‐Controlled Trial
Allergy, EarlyView.This is the first randomised placebo‐controlled trial of intralymphatic immunotherapy using a microcrystalline tyrosine‐adjuvanted grass pollen allergoid. Three ultrasound‐guided ILIT injections were well tolerated and reduced combined symptom‐medication scores compared with placebo. The findings support further optimisation and clinical development of Lara Šošić, Stephan C. Flory, Claudia C. V. Lang, Emma C. Widmer, Alexandra Chabot, Johannes M. Schmid, Tobias Andermatt, David Melillo, Bjarke Hviid‐Vyff, Maibritt Mardahl, Peter Schmid‐Grendelmeier, Thomas M. Kündig, Hans Jürgen Hoffmann, Pål Johansen +13 morewiley +1 more sourceTransition between subcutaneous and sublingual allergen immunotherapy: Recommendations of the Brazilian Association of Allergy and Immunology (ASBAI)
Journal of Allergy and Clinical Immunology: GlobalThe use of allergen immunotherapy (AIT) in Brazil has specific regional conditions owing to the pattern of allergen sensitization, as well as to genetic, socioeconomic, and cultural characteristics.Fernando Monteiro Aarestrup, MD, PhD, Ernesto Akio Taketomi, MD, PhD, Clóvis Eduardo Santos Galvão, MD, PhD, Gil Bardini Alves, MD, MSc, Geórgia Véras de Araújo Gueiros Lira, MD, PhD, Marcos Reis Gonçalves, MD, MSc, Mariana Graça Couto Miziara, MD, Sidney Souteban Maranhão Casado, MD, Veridiana Aun Rufino Pereira, MD, PhD, Dirceu Solé, MD, PhD, Ekaterini Simoes Goudouris, MD, PhD, Fabio Chigres Kuschnir, MD, PhD +11 moredoaj +1 more sourceDistinct Gene Expression Profiles of Ara h 2‐Specific B Cells in Desensitization and Tolerance During Peanut Oral Immunotherapy
Allergy, EarlyView.Gene expression of Ara h 2‐specific B cells over the course of the peanut OIT. Isotype of allergen‐specific B cells changes through OIT towards IgG4. Peanut OIT changes the gene expression of allergen‐specific memory B cells. OIT patients showed increased gene expression for regulatory B cells and immune regulation.Stephan R. Schneider, Juan‐Felipe López, Huseyn Babayev, Willem van de Veen, Minglin Yang, Cezmi A. Akdis, Kari Nadeau, Carolyn H. Baloh, Stacie M. Jones, Lisa M. Wheatley, Mübeccel Akdis, IMPACT, Amy M. Scurlock, D. Pesek, Joy Laurienzo‐Panza, Marshall Plaut, A. Wesley Burks, Edwin H. Kim, Mike Kulis, Anna Nowak‐Wegrzyn, Hugh A. Sampson, Julie Wang, Robert A. Wood, Sharon Chinthrajah, Robert Sayantani B. Sindher, Jacqueline Johnson, Katharine Spain, Denise C. Babineau, Hyunsook Chin, Rachel Yan, Don Whitehouse, Michelle L. Sever, Srinath Sanda, David Larson, Tielin Qin, Gina Marchesini, Kavitha Gilroy, Sylvia Posso, Sabrina Skiba, Thien‐Son Nguyen, Adam Wojno, Tuan Nguyen, Vivian Gersuk, Quynh‐Anh Nguyen, Jessica Garber, Kimberly O'Brien, Brandon Larson, C. Cousens‐Jacobs, Alex Hu +48 morewiley +1 more source
