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Modified Allergens for Immunotherapy
Current Allergy and Asthma Reports, 2018During the past few decades, modified allergens have been developed for use in allergen-specific immunotherapy (AIT) with the aim to improve efficacy and reduce adverse effects. This review aims to provide an overview of the different types of modified allergens, their mechanism of action and their potential for improving AIT.In-depth research in the ...
Satitsuksanoa, Pattraporn +4 more
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JAMA: The Journal of the American Medical Association, 1997
Allergen immunotherapy has been shown to be efficacious in numerous studies for the clinical indications of allergic asthma and rhinitis, as well as hymenoptera venom hypersensitivity. How allergen immunotherapy improves clinical symptoms is still not entirely clear.
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Allergen immunotherapy has been shown to be efficacious in numerous studies for the clinical indications of allergic asthma and rhinitis, as well as hymenoptera venom hypersensitivity. How allergen immunotherapy improves clinical symptoms is still not entirely clear.
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JAMA: The Journal of the American Medical Association, 1987
ALLERGEN immunotherapy is the process by which increasing doses of allergen are injected subcutaneously over time as a treatment to prevent allergic symptoms that usually occur on exposure to allergen. The effects of this therapy on the immunologic processes ascribed to allergic responses have been studied in great detail.
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ALLERGEN immunotherapy is the process by which increasing doses of allergen are injected subcutaneously over time as a treatment to prevent allergic symptoms that usually occur on exposure to allergen. The effects of this therapy on the immunologic processes ascribed to allergic responses have been studied in great detail.
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Allergy and Asthma Proceedings, 2022
Venom immunotherapy (VIT) with Hymenoptera venom extracts is highly effective in preventing large local, systemic allergic, and anaphylactic reactions to insect stings. VIT is not required for patients with cutaneous systemic or large local allergic reactions to stings because it is uncommon for reactions to become more severe.
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Venom immunotherapy (VIT) with Hymenoptera venom extracts is highly effective in preventing large local, systemic allergic, and anaphylactic reactions to insect stings. VIT is not required for patients with cutaneous systemic or large local allergic reactions to stings because it is uncommon for reactions to become more severe.
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Primary Care: Clinics in Office Practice, 2016
Allergies affect a large proportion of the population. Allergies can adversely affect productivity, sleep, and quality of life and can lead to life-threatening reactions. Allergies can spread to affect multiple organ systems. Allergen immunotherapy is the only therapy that can change the natural history of allergic disease.
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Allergies affect a large proportion of the population. Allergies can adversely affect productivity, sleep, and quality of life and can lead to life-threatening reactions. Allergies can spread to affect multiple organ systems. Allergen immunotherapy is the only therapy that can change the natural history of allergic disease.
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Mechanisms of Allergen Immunotherapy
Allergy & Clinical Immunology International - Journal of the World Allergy Organization, 2004SummaryThe molecular and cellular mechanisms of allergen‐specific immunotherapy (SIT) have recently been investigated. It appears that, similar to a normal immune response to allergen, the generation of allergen‐specific, regulatory/suppressor T cells plays a key role in succcessful SIT. T cells before and after SIT and exposure to high allergen doses,
M. Akdis +4 more
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Allergen Immunotherapy for Asthma
The Journal of Allergy and Clinical Immunology: In PracticeAllergen immunotherapy is a disease-modifying treatment for IgE-mediated allergies reducing disease burden and symptoms in patients with allergic rhinitis, with or without asthma. The growing evidence that allergen immunotherapy also has the potential to facilitate achieving asthma control in patients with allergic asthma resulted in its acknowledgment
Jasper H, Kappen +4 more
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Allergen immunotherapy and asthma
Pediatric Allergy and Immunology, 2020AbstractAllergen immunotherapy (AIT) represents at present the unique disease‐modifying treatment strategy for IgE‐mediated allergic diseases. AIT can induce clinical improvement of allergic asthma, including reduced symptoms, medication use, and improvement of quality of life, with a long‐lasting effect after cessation of treatment.
Maria Angela Tosca +3 more
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Allergens and Allergen Immunotherapy
2020Basics Allergen Immunotherapy in a Historical Perspective David Fitzhugh, Sheldon G. Cohen, and Richard Evans III (deceased) Definition of an Allergen (Immunobiology) Malcolm N. Blumenthal and Lauren Fine Allergen Nomenclature Heimo Breiteneder and Martin D. Chapman Immunological Responses to Subcutaneous Allergen Immunotherapy Mohamed H.
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Allergen-Specific Immunotherapy
2014Specific immunotherapy was introduced for the treatment of grass pollen-induced hay fever in 1911. The treatment was soon extended to other pollens as well as perennial allergens, and to the treatment of bronchial asthma. Definitive studies of its efficacy for both rhinitis and asthma came only many decades later. Understanding gradually emerged of the
Harold S, Nelson, Philip S, Norman
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