SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.
Michael B. Murphy +17 more
wiley +1 more source
<i>Association of Dermatophagoides pteronyssinus</i>-specific immunoglobulin epsilon with atopy, age, and gender in a Filipino population. [PDF]
Alberba IJP +7 more
europepmc +1 more source
Assessing the sensitisation hazard of microbial pesticides: potential value of New Approach Methodologies (NAMs) to overcome current challenges. [PDF]
Leme DM +5 more
europepmc +1 more source
Safety evaluation of the food enzyme subtilisin from the genetically modified <i>Bacillus subtilis</i> strain DP-Ezx62. [PDF]
EFSA Panel on Food Enzymes (FEZ) +17 more
europepmc +1 more source
Direct in vivo evidence for mast cell degranulation during allergen-induced reactions in man
Eva Gómez‐Orte +4 more
openalex +1 more source
Insights into Local Grass and Weed Pollen Sensitization in Bangkok, Thailand: IgE Reactivity Patterns, Cross-Reactivity, and Putative Allergens. [PDF]
Aud-In S +3 more
europepmc +1 more source
Skin reactivity to purified pollen allergens in highly ragweed-sensitive individuals
John Santilli +3 more
openalex +1 more source
Multimodal deep learning for allergenic proteins prediction. [PDF]
Yu L +6 more
europepmc +1 more source

