Results 161 to 170 of about 936,865 (297)

Therapeutic JAK Inhibition in Idiopathic Subglottic Stenosis

The Laryngoscope, EarlyView.
Three patients with idiopathic subglottic stenosis and rheumatoid arthritis began JAK inhibitor therapy, after which the mean surgical‐free interval between endoscopic dilations rose from 317 to 631 days and the annualized dilation rate fell from 1.24 to 0.38 per patient‐year. Figure 2 shows this as a per‐patient timeline.
Riley M. Larkin, Ioan Lina, Julianna Kostas, Caroline Christmann, Kevin Byram, Alexander Gelbard   +5 more
wiley   +1 more source

IL-9 Is Essential for ILC2-Mediated but Not Th2- and Th17-Cell-Mediated Allergic Airway Inflammation in Mice. [PDF]

Eur J Immunol
Sidiropoulos ND, Ampenberger F, Schlapbach C, Schneider C, Kopf M.   +4 more
europepmc   +1 more source

Novel Injectable Supports Long‐Term Recurrent Laryngeal Nerve and Partial Peripheral Nerve Repair

The Laryngoscope, EarlyView.
Following recurrent laryngeal nerve transection in C57BL/6 mice, intramuscular Agrin, neuregulin‐1, and acetylcholine treatment of the thyroarytenoid muscle supported functional reinnervation and preservation of neuromuscular structure at 84 days.
Aditya Bhatt, William Boswell, Elena Kennedy, Sunjay Anekal, Emma Mazurek, Ananya Tadikonda, Christopher Rafalko, Jasmine Strelow, Isaac Shipchandler, Patrick R. Finnegan, Stacey Halum   +10 more
wiley   +1 more source

Pollen-derived extracellular vesicles promotes allergic airway inflammation. [PDF]

Front Immunol
Shang T, Li J, Ru Y, Guan K.
europepmc   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Activation of lung megakaryocyte α7 nAChR exacerbates allergic airway inflammation via IL-33/p38 MAPK signaling. [PDF]

JCI Insight
Wu H, Tao R, Xie S, Zhou Y, Xu JF, Xia Z, Su X.   +6 more
europepmc   +1 more source

Deciphering the Inflammatory Network in Pediatric Recurrent Tonsillitis: The Role of TRAF6, IRAK1, and miR‐146a‐5p

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To investigate the role of TNF receptor‐associated factor 6 (TRAF6), interleukin 1 receptor‐associated kinase 1 (IRAK1), and miR‐146a‐5p expression levels in the pathogenesis of recurrent tonsillitis. Study Design Case‐control study. Setting The study was conducted at the Department of Otorhinolaryngology, Muğla Training and Research
Ömer Faruk Güzel, Çilem Özdemir, Tuba Edgünlü, Ozan Gökdoğan   +3 more
wiley   +1 more source

Bronchial Fibroblasts Respond to IL-4 Challenge With Cytokine Secretion: Role in Allergic Airway Inflammation. [PDF]

Clin Exp Allergy
Zhang D, Liu W, Chen Q, Han S, Wang T, Qi Q, Dong L, Wang X.   +7 more
europepmc   +1 more source

Efficacy of Exhalation Delivery System With Fluticasone in Chronic Rhinosinusitis With Versus Without Polyps

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate whether treatment responses to the exhalation delivery system with fluticasone (EDS‐FLU; XHANCE®) differ between patients with CRS with nasal polyps (CRSwNP) and patients without nasal polyps (CRSsNP). Study Design Post hoc analysis of the ReOpen clinical trials conducted between November 2018 and November 2021 for a 24 ...
Rodney J. Schlosser, Nithin D. Adappa, Rakesh K. Chandra, Greg E. Davis, Mahboobeh Mahdavinia, John Messina, Zara M. Patel, Anju T. Peters, Raj Sindwani, Zachary M. Soler, Andrew A. White, Sarah K. Wise, James N. Palmer   +12 more
wiley   +1 more source

SREBP2 promotes macrophage alternative activation and allergic airway inflammation independent of cholesterol biosynthesis. [PDF]

Cell Death Dis
Wu Y, Zheng K, Dong L, Gao S, Wu Y, Liu Z, Li J, Chen H, Weng Q, Li M, Zhu C, Xu J, Ying S, Chen Z, Li W.   +14 more
europepmc   +1 more source