Results 111 to 120 of about 126,196 (312)

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

open access: yesiNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng   +3 more
wiley   +1 more source

Gut microbiome‐derived metabolites show promise in cancer research and therapy

open access: yesInterdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang   +4 more
wiley   +1 more source

Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma [PDF]

open access: gold, 2017
Sabine Bartel   +12 more
openalex   +1 more source

An Evaluation of a Molecular Point‐of‐Care Testing System Designed for Early Diagnosis of Mycoplasma pneumoniae and Respiratory Syncytial Virus Infections

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
On the basis of RT‐qPCR results, 549 oropharyngeal swabs were classified into four groups: MP‐positive (n = 109), MP‐negative (n = 160), RSV‐positive (n = 122), and RSV‐negative (n = 158). Using these as the reference standard, we evaluated a molecular point‐of‐care testing (mPOCT) system (EasyNAT) for simultaneous MP and RSV detection.
Yang Su   +13 more
wiley   +1 more source

A randomized controlled trial of home‐applied dual‐light photodynamic therapy during supportive periodontal care (HOPE‐CP study)

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis is a common, chronic inflammatory disease that relies heavily on effective daily oral hygiene for long‐term control. Light‐based therapies have demonstrated strong antibacterial potential; however, their effectiveness in regular home use remains unexplored.
Saila Pakarinen   +10 more
wiley   +1 more source

Beyond eosinophils: A proteomic dissection of remodeling and inflammation in suspected eosinophilic esophagitis

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Eosinophilic esophagitis (EoE) is characterized by eosinophilic inflammation and epithelial remodeling. However, current biomarkers focus predominantly on eosinophilia, overlooking basal cell hyperplasia (BCH), a histologic feature that may persist despite treatment.
Adi Eindor‐Abarbanel   +7 more
wiley   +1 more source

Lifetime asthma incidence is related to age at onset and allergies in western Sweden

open access: yesClinical and Translational Allergy
Although asthma is more frequently diagnosed in childhood, a substantial proportion of cases manifests in adulthood. Nonetheless, few studies have comprehensively examined asthma incidence across different ages, genders, and asthma phenotypes.
Reshed Abohalaka   +9 more
doaj   +1 more source

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