Results 21 to 30 of about 221,385 (308)
Risk for Postmarket Black Box Warnings in FDA-Approved Monoclonal Antibodies
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2022 Objective: To estimate the potential risk for a future postmarket black box warning (BBW) of US Food and Drug Administration (FDA)-approved monoclonal antibodies (mAbs) because of the importance for medical clinicians to understand mAb risks and benefits,
John B. Hagan, MD +4 more
doaj +1 more source
Does adiposity mediate the relationship between socioeconomic position and non-allergic asthma in childhood? [PDF]
, 2018 BACKGROUND: Despite its high prevalence, early onset and chronic nature, the causes of asthma are not clearly established. The present study examined a plausible but untested relationship in the development of non-allergic asthma; an asthma phenotype ...
Lewis, KM, Morrison, J, Pikhart, H
core +1 more source
Methemoglobinemia during the Use of Glyceryl Trinitrate Patches in Neonates: Two Case Reports
American Journal of Perinatology Reports, 2018 Methemoglobinemia can result in severe hypoxia. It has been frequently reported during the use of inhaled nitric oxide, but can occur where nitrate containing medications are used.
Alison Mintoft +4 more
doaj +1 more source
Age-specific incidence of allergic and non-allergic asthma
BMC Pulmonary Medicine, 2020 Background Onset of allergic asthma has a strong association with childhood but only a few studies have analyzed incidence of asthma from childhood to late adulthood in relation to allergy. The purpose of the study was to assess age-specific incidence of
Johanna Pakkasela +12 more
doaj +1 more source
Journal of Lipid Research, 2018 In patients with asthma or chronic obstructive pulmonary disease, rhinovirus (RV) infections can provoke acute worsening of disease, and limited treatment options exist.
An Nguyen +8 more
doaj +1 more source
Airway responses and inflammation in subjects with asthma after four days of repeated high-single-dose allergen challenge [PDF]
, 2012 Background: Both standard and low-dose allergen provocations are an established tool in asthma research to improve our understanding of the pathophysiological mechanism of allergic asthma.
Rose, Markus A. +5 more
core +2 more sources
Eosinophilic Inflammation in Allergic Asthma [PDF]
Frontiers in Pharmacology, 2013 Eosinophils are circulating granulocytes involved in pathogenesis of asthma. A cascade of processes directed by Th2 cytokine producing T-cells influence the recruitment of eosinophils into the lungs. Furthermore, multiple elements including interleukin (IL)-5, IL-13, chemoattractants such as eotaxin, Clara cells, and CC chemokine receptor (CCR)3 are ...
Possa, Samantha S. +4 more
openaire +4 more sources
Pediatric Selective IgM Immunodeficiency
Clinical and Developmental Immunology, 2008 Objective. Limited information exists on features of pediatric Selective IgM immunodeficiency (SIgMID). Previously published pediatric cases and 2 new cases are reviewed. Methods.
Marc F. Goldstein +5 more
doaj +1 more source
Аллергология и Иммунология в Педиатрии, 2023 Introduction. Today there has been a steady increase in the allergic pathology of the respiratory tract - bronchial asthma and allergic rhinitis in pediatric practice.
R. Z. Tikhonova, R. M. Fayzullina
doaj +1 more source
Shh production and Gli signaling is activated in vivo in lung, enhancing the Th2 response during a murine model of allergic asthma [PDF]
, 2017 The pathophysiology of allergic asthma is driven by T-helper 2 (Th2) immune responses following aeroallergen inhalation. The mechanisms that initiate, potentiate and regulate airways allergy are incompletely characterized.
Crompton, Tessa +4 more
core +3 more sources