Results 21 to 30 of about 126,196 (312)

Eosinophilic Inflammation in Allergic Asthma [PDF]

open access: yesFrontiers in Pharmacology, 2013
Eosinophils are circulating granulocytes involved in pathogenesis of asthma. A cascade of processes directed by Th2 cytokine producing T-cells influence the recruitment of eosinophils into the lungs. Furthermore, multiple elements including interleukin (IL)-5, IL-13, chemoattractants such as eotaxin, Clara cells, and CC chemokine receptor (CCR)3 are ...
Possa, Samantha S.   +4 more
openaire   +4 more sources

Pediatric Selective IgM Immunodeficiency

open access: yesClinical and Developmental Immunology, 2008
Objective. Limited information exists on features of pediatric Selective IgM immunodeficiency (SIgMID). Previously published pediatric cases and 2 new cases are reviewed. Methods.
Marc F. Goldstein   +5 more
doaj   +1 more source

United Kingdom Oscillation Study: long-term outcomes of a randomised trial of two modes of neonatal ventilation

open access: yesHealth Technology Assessment, 2014
Background: One in 200 infants in the UK is born extremely prematurely, i.e. before 29 weeks of gestation. Seventy-five per cent of such infants survive, but many have long-term respiratory and/or functional problems.
Anne Greenough   +6 more
doaj   +1 more source

Causal relationship between Butyricimonas and allergic asthma: a two-sample Mendelian randomization study

open access: yesFrontiers in Microbiology, 2023
BackgroundGrowing evidence has well documented the close association between the gut microbiome and allergic respiratory disease, which has been notably represented by allergic asthma.
Wei Wan   +5 more
doaj   +1 more source

Allergen Immunotherapy in Asthma

open access: yesPathogens, 2021
Allergen immunotherapy (AIT) is a specific treatment involving the administration of relevant allergens to allergic patients, with subtypes including subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT).
Kazuyuki Nakagome, Makoto Nagata
doaj   +1 more source

Complements and allergic asthma

open access: yesPediatric Respirology and Critical Care Medicine, 2019
Regulatory T (Treg) cells play a central role in protecting against the development of allergic asthma and interleukin-10 (IL-10) producing T regulatory type 1 (Tr1) cells contribute to the regulation of asthma. Complement regulatory protein CD46 was shown to stimulate the development of IL-10 producing Tr1 cells.
Ching-Yuang Lin, Yi-Giien Tsai
openaire   +2 more sources

Omalizumab for Severe Asthma: Beyond Allergic Asthma [PDF]

open access: yesBioMed Research International, 2018
Different subsets of asthma patients may be recognized according to the exposure trigger and the frequency and severity of clinical signs and symptoms. Regarding the exposure trigger, generally asthma can be classified as allergic (or atopic) and nonallergic (or nonatopic). Allergic and nonallergic asthma are distinguished by the presence or absence of
C. C. Loureiro   +7 more
openaire   +5 more sources

Does unified allergic airway disease impact on lung function and type 2 biomarkers?

open access: yesAllergy, Asthma & Clinical Immunology, 2019
The concept of the unified allergic airway disease (UAD) recognises the association between allergic inflammation in the upper and lower airways. Patients with asthma and concomitant allergic rhinitis experience more asthma-related primary and secondary ...
Chris RuiWen Kuo   +2 more
doaj   +1 more source

Updates on functional characterisation of bronchopulmonary dysplasia – the contribution of lung function testing

open access: yesFrontiers in Medicine, 2015
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that predominantly affects prematurely born infants. Initially BPD was described in infants who had suffered severe respiratory failure and required high pressure, mechanical ventilation with ...
Anne eGreenough   +2 more
doaj   +1 more source

Asthma and Allergic Inflammation [PDF]

open access: yesCell, 2010
Studies of the initiation and maintenance of asthma and allergic inflammation implicate dysregulated interactions between mucosal epithelia and innate immune cells as the underlying cause of these disorders. The similarities of these responses with mucosal responses to parasitic intestinal worms may reveal pathways relevant to the perplexing rise of ...
openaire   +2 more sources

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