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Allergic Proctocolitis: Literature Review and Proposal of a Diagnostic-Therapeutic Algorithm. [PDF]

Life, 2023
Allergic proctocolitis (AP) is a benign condition, frequent in childhood, that is classified as a non-IgE-mediated food allergy. The prevalence is unknown; however, its frequency appears to be increasing, especially in exclusively breastfed infants ...
Simona Barni, Francesca Saretta, Mattia Giovannini   +2 more
exaly   +10 more sources

The Immunological Mechanisms Involved in the Pathophysiology of Allergic Proctocolitis [PDF]

Children
Background: The pathophysiology of non-IgE-mediated cow’s milk allergy is mostly unknown. Previous studies suggested a mechanism mediated by T cells, but this was not confirmed in subsequent studies.
Jimena Pérez-Moreno, Esther Bernaldo-de-Quirós, Mar Tolín Hernani, Guillermo Álvarez-Calatayud, Laura Perezábad, César Sánchez Sánchez, Rafael Correa-Rocha   +6 more
doaj   +5 more sources

Analysis of Clinical Characteristics of Refractory Food Protein-Induced Allergic Proctocolitis [PDF]

Children
Background/Objectives: Food protein-induced allergic proctocolitis (FPIAP) is a non-immunoglobulin-E-mediated allergic colitis. Most cases resolve after 1 year of age, but delayed resolution and growth retardation may occur in some refractory cases.
Juan Zhang, Hui Wu, Jun Li, Xun Liu, Xueying Shi, Hua Zhang, Zailing Li   +6 more
doaj   +6 more sources

A Rare Case of Cow’s Milk Protein Allergy in a 12-Hour Old Neonate With Rectal Bleeding [PDF]

Case Reports in Pediatrics
Hematochezia presenting in the neonatal period requires a thorough exploration of life-threatening and benign pathologies, including food protein–induced allergic proctocolitis (FPIES).
Isona Kakuchi, Alexa Giroud Rivier, Estelle Dubruc, Céline J. Fischer Fumeaux, Sébastien Joye   +4 more
doaj   +3 more sources

Food Protein-Induced Allergic Proctocolitis: The Effect of Maternal Diet During Pregnancy and Breastfeeding in a Mediterranean Population [PDF]

Frontiers in Nutrition, 2022
BackgroundThe aim of the current investigation was to explore the association of food protein-induced allergic proctocolitis (FPIAP) with the maternal diet during pregnancy and breastfeeding in Greek infants.MethodsA multicenter retrospective case ...
Gavriela Feketea, Emilia Vassilopoulou, Nikolaos G Papadopoulos   +2 more
exaly   +4 more sources

Food protein-induced allergic proctocolitis in infants: Literature review and proposal of a management protocol [PDF]

World Allergy Organization Journal, 2020
Food protein-induced allergic proctocolitis (FPIAP) is a condition characterized by inflammatory changes in the distal colon in response to one or more foreign food proteins because of immune-mediated reactions.FPIAP prevalence estimates range widely ...
Maurizio Mennini, Alessandro Giovanni Fiocchi, Arianna Cafarotti, Marilisa Montesano, Angela Mauro, Maria Pia Villa, Giovanni Di Nardo   +6 more
doaj   +4 more sources

Longitudinal disease-associated gut microbiome differences in infants with food protein-induced allergic proctocolitis [PDF]

Microbiome, 2022
Background Complex interactions between the gut microbiome and immune cells in infancy are thought to be part of the pathogenesis for the marked rise in pediatric allergic diseases, particularly food allergies. Food protein-induced allergic proctocolitis
Victoria M. Martin, Yamini V. Virkud, Ehud Dahan, Hannah L. Seay, Dvir Itzkovits, Hera Vlamakis, Ramnik Xavier, Wayne G. Shreffler, Qian Yuan, Moran Yassour   +9 more
doaj   +2 more sources

Gut Microbiota Differences in Infants with Cow-Milk-Induced Allergic Proctocolitis: A Comparative Cross-Sectional Study [PDF]

Children
Background: Cow-milk-induced allergic proctocolitis (CMIAP) is a non-IgE-mediated food hypersensitivity that often resolves spontaneously but may predispose infants to IgE-mediated allergies and eosinophilic gastrointestinal disorders.
Zeliha Haytoglu, Dilek Ozcan, Derya Ufuk Altintas   +2 more
doaj   +2 more sources

Portal vein thrombosis and food protein-induced allergic proctocolitis in a premature newborn with hypereosinophilia: a case report [PDF]

BMC Pediatrics, 2021
Background Peripheral blood eosinophilia is identified in numerous medical conditions associated with allergic, infectious, and inflammatory processes mostly as reactive eosinophilia with or without tissue eosinophilia.
Cheong-Jun Moon, Tae Hee Kwon, Hyun-Seung Lee   +2 more
doaj   +2 more sources

Strain-level microbial signatures and inferred functional alterations in infants with food protein-induced allergic proctocolitis [PDF]

Genome Medicine
Background The complex relationship between the gut microbiome and immune system development during infancy is considered a key factor in the rising rates of pediatric allergic diseases.
Chen Goldstein, Itamar Lavy, Timothy Sun, Dena Ennis, Wayne G. Shreffler, Qian Yuan, Yamini V. Virkud, Victoria M. Martin, Moran Yassour   +8 more
doaj   +2 more sources