Results 51 to 60 of about 217,585 (300)

CpG-ODN Signaling via Dendritic Cells-Expressing MyD88, but Not IL-10, Inhibits Allergic Sensitization

Vaccines, 2021
Allergen-specific T helper (Th)2 cells orchestrate upon allergen challenge the development of allergic eosinophilic lung inflammation. Sensitization with alum adjuvant, a type 2 adjuvant, has been used extensively in animal models of allergic lung ...
Ricardo Wesley Alberca, Eliane Gomes, Momtchilo Russo   +2 more
doaj   +1 more source

Maternal intake of fatty acids during pregnancy and allergies in the offspring [PDF]

, 2011
Fatty acids (FA) are known to have a number of immunological effects and, accordingly, may play a role in the development of allergic diseases. We investigated the effect of maternal intake of FA during pregnancy on the risk of allergic rhinitis, wheeze ...
Veijola, Riitta, Maijaliisa Erkkola, Jorma Ilonen, Suvi Ahonen, Erkkola, Maijaliisa, Riitta Veijola, Suvi M. Virtanen, Mikael Knip, Knip, Mikael, Virtanen, Suvi M., Kronberg-Kippila, Carina, Simell, Olli, Mirka Lumia, Minna Kaila, Nwaru, Bright I., Kaila, Minna, Nwaru, Bright I, Olli Simell, Bright I. Nwaru, Lumia, Mirka, Virtanen, Suvi M, Ilonen, Jorma, Carina Kronberg-Kippilä, Ahonen, Suvi   +23 more
core   +1 more source

Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan, Boliang Wang, Fiona Dobson, Ben Kirk, Travis Haber, Kim L. Bennell, Shirley P. Yu, Kim Allison, Ricardo J. S. Costa, Gabrielle Knox, Michelle Hall   +10 more
wiley   +1 more source

Neutrophil recruitment by allergens contribute to allergic sensitization and allergic inflammation [PDF]

Current Opinion in Allergy & Clinical Immunology, 2016
To discuss the presence and role of neutrophils in asthma and allergic diseases, and outline the importance of pollen and cat dander-induced innate neutrophil recruitment in induction of allergic sensitization and allergic inflammation.Uncontrolled asthma is associated with elevated numbers of neutrophils, and levels of neutrophil-attracting chemokine ...
Koa, Hosoki, Toshiko, Itazawa, Istvan, Boldogh, Sanjiv, Sur   +3 more
openaire   +2 more sources

Self-Reported Truck Traffic on the Street of Residence and Symptoms of Asthma and Allergic Disease: A Global Relationship in ISAAC Phase 3 [PDF]

, 2009
BACKGROUND: Associations between traffic pollution on the street of residence and a range of respiratory and allergic outcomes in children have been reported in developed countries, but little is known about such associations in developing countries ...
H. Ross Anderson, Anderson, HR, Strachan, DP, Pearce, Neil, David P. Strachan, ISAAC Phase 3 Study Group, Christopher K.W. Lai, Anderson, H Ross, Lai, CK, Bert Brunekreef, Pearce, N, Stewart, AW, Neil Pearce, Stewart, Alistair W, ?, ?, Lai, Christopher KW, Strachan, David P, Lai, Christopher K W, Alistair W. Stewart, Brunekreef, B, Brunekreef, Bert   +20 more
core   +1 more source

A Scoping Review and Meta‐Analysis of Proportions of Central Nervous System Manifestations Reported in Patients with Sjögren's Disease

Arthritis Care &Research, Accepted Article.
Objective The objective of this scoping review was to synthesize evidence on the proportion of individuals living with Sjögren's disease who experience central nervous system (CNS) manifestations. Methods We searched MEDLINE (via PubMed) and Embase from 1980 through January 29, 2026, and the ECRI Guidelines Trust from 2020 through January 29, 2026 ...
Arun Varadhachary, Ghaith Noaiseh, Julie Frantsve‐Hawley, Frederick B. Vivino, Jennifer A. McCombe, Shamik Bhattacharyya, E. Sherwood Brown, Andrew R. Carey, Robert Fox, Thomas Grader‐Beck, Janet E. Lewis, Stephen Maitz, Steven Mandel, Astrid Rasmussen, George Sarka, R. Hal Scofield, Daniel J. Wallace, Rochelle Zak, Kristie Cox, Katherine M. Hammitt, Steven Carsons, Nancy Carteron   +21 more
wiley   +1 more source

Dietary fibre in relation to asthma, allergic rhinitis and sensitization from childhood up to adulthood

Clinical and Translational Allergy, 2022
Background Dietary fibre may reduce the risk of allergy. Our aim was to investigate the association between fibre intake in childhood, asthma, allergic rhinitis and IgE sensitization up to adulthood.
Emmanouela Sdona, Sandra Ekström, Niklas Andersson, Niclas Håkansson, Alicja Wolk, Marit Westman, Marianne vanHage, Inger Kull, Erik Melén, Anna Bergström   +9 more
doaj   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Natural Course of Allergic and Nonallergic Rhinitis After 2 Years in Korean Children [PDF]

Clinical and Experimental Otorhinolaryngology, 2016
Objectives. Allergic and nonallergic rhinitis are very common disease for children, however, little is known about their natural courses in the general population.
Seung-Hoon Lee, Ji Ho Choi, Jeffrey D. Suh, Sochung Chung, Seok-Chan Hong, Jin Kook Kim, Jae Hoon Cho   +6 more
doaj   +1 more source