Results 71 to 80 of about 217,585 (300)

Gut‐Liver Translocation of Bacteroides Uniformis Alleviates Advanced Metabolic Dysfunction‐Associated Steatotic Liver Disease by Suppressing Hepatocyte Ferroptosis via Propionic Acid Secretion

Advanced Science, EarlyView.
Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu, Zun Fan, Zhen Liu, Lei Qin, Xin Zhao   +4 more
wiley   +1 more source

Lower expression of TLR2 and SOCS-3 is associated with Schistosoma haematobium infection and with lower risk for allergic reactivity in children living in a rural area in Ghana. [PDF]

, 2008
BACKGROUND: Helminth infections are prevalent in rural areas of developing countries and have in some studies been negatively associated with allergic disorders and atopy. In this context little is known of the molecular mechanisms of modulation involved.
Larbi, Irene A., Larbi, Irene A, Obeng, Benedicta B., Wilson, Michael D, de Breij Anna, Kruize, Yvonne CM, Hartgers, Franca C., Marjolijn Duijvestein, van Ree, Ronald, Larbi Irene A., Amoah, Abena, Wilson, Michael D., Michael D Wilson, Boakye Daniel A., Boakye, Daniel A, Duijvestein, Marjolijn, Yvonne C M Kruize, Amoah Abena, Hartgers, Franca C, Franca C Hartgers, Obeng, Benedicta B, Yazdanbakhsh, Maria, Obeng Benedicta B., Rodrigues Laura C., Duijvestein Marjolijn, Yazdanbakhsh Maria, Hartgers Franca C., Anna de Breij, Ronald van Ree, Benedicta B Obeng, Irene A Larbi, Boakye, Daniel A., Wilson Michael D., Kruize Yvonne C. M., Abena Amoah, de Breij, Anna, Laura C Rodrigues, Kruize, Yvonne C. M., Rodrigues, Laura C., Rodrigues, Laura C, Maria Yazdanbakhsh, Daniel A Boakye, van Ree Ronald   +42 more
core   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Activation of TLR Signaling in Sensitization-Recruited Inflammatory Monocytes Attenuates OVA-Induced Allergic Asthma

Frontiers in Immunology, 2018
The activation of Toll-like receptor (TLR) signaling is widely reported to be involved in preventing the development of allergic asthma. However, the mechanism of the protective function of TLR signaling remains limited.
Chao Huang, Jian Wang, Xiaodong Zheng, Yongyan Chen, Haiming Wei, Haiming Wei, Rui Sun, Rui Sun, Zhigang Tian, Zhigang Tian   +9 more
doaj   +1 more source

Adaptive Conductive Systems: Enabling Deformable Electronics Through Engineered Materials, Circuits, and Intelligent Systems

Advanced Science, EarlyView.
This review presents the research advances of adaptive conductive systems from the perspective of materials, circuits, systems, and applications. Deformable conductors consist of substrates/matrices and conductive materials, structural design of circuit interconnections, fabrication of circuit interconnections, as well as intelligent systems ...
Yufei Lu, Siyu Liang, Jingyi Niu, Jie Chen, Shuo Zhang, Hongjian Zhang, Dongsheng Jia, Wei Huang   +7 more
wiley   +1 more source

Skin Prick Testing in a Portuguese Pediatric Population: A Multicenter Cross-Sectional Study of Clinical and Allergen Sensitization Profiles

Acta Médica Portuguesa
Introduction: Allergic diseases, particularly allergic rhinitis and asthma are highly prevalent among children and adolescents and frequently associated with sensitization to inhalant allergens.
Manuel Lima Ferreira, João Nogueira Oliveira, Mariana Pinto, Arménia Oliveira, Paulo Guimarães, Aida Azevedo, Filipa Almeida, Fernanda Carvalho, Inês Falcão, Maria José Dinis, Conceição Silva, Rita S. Pereira, Raquel S. Santos, Márcia Quaresma, André Assunção, Diana Bordalo, Sylvia Jacob, David Gomes, Hunilla Jacinto, António Bento Guerra, Sofia Guedes, Patrícia Silva, Daniela Henriques, Armandina Silva, Marta Santalha, Teresa São Simão, Inês Eiras, Mariana Santos Nobre, Helena Ramalho, Rita Salgueiro, Lara Torres, Pedro Guerra, Rita Barroca, Ana Luísa Correia, Georgeta Oliveira, Rita Lages Pereira, Fábia Carvalho, Margarida Reis Morais, Diana S. Pinto, Ana Rita Araújo, Mafalda Moreira, Sandra Teixeira   +41 more
doaj   +1 more source

Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients

Annals of Neurology, EarlyView.
Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer, Seth Frietze, Serena W.R. Lewis, Emily C. Artman, Christina Coughlan, Safa I. Vaseemuddin, Arianna Gentile Polese, Maria A. Nagel, Stephen K. Tyring, Fyona Okundia, Anthony J. Saviola, Gary C. Curhan, Sharon G. Curhan, Diego Restrepo, Andrew N. Bubak   +14 more
wiley   +1 more source

IgE Sensitization to Inhalant Allergens and Its Association with Allergic Diseases in Adults

Iranian Journal of Allergy, Asthma and Immunology, 2018
Allergic sensitization to inhalant allergens could be considered as a predictor in allergic diseases. The objective of this study was to assess IgE-mediated sensitization to inhalant allergens in allergic and non-allergic adults as well as the evaluation
Raheleh Shokouhi Shoormasti, Mohammad Reza Fazlollahi, Anoshirvan Kazemnejad, Behnoosh Tayebi, Fatemeh Nadali, Maryam Sharif Shoushtari, Shamim Khandan Alamdari, Majid Moslemi, Masoud Movehdi, Adriano Mari, Zahra Pourpak, Mostafa Moin   +11 more
doaj  

Exploring Molecular Responses to Aeroallergens in Respiratory Allergy Across Six Locations in Peru

Allergies
Allergic diseases, particularly respiratory allergies like asthma and allergic rhinitis, are a growing public health concern influenced by environmental factors such as climate change and air pollution.
Oscar Manuel Calderón-Llosa, César Alberto Galván, María José Martínez, Ruperto González-Pérez, Eva Abel-Fernández, Fernando Pineda   +5 more
doaj   +1 more source

Combinations of self‐reported rhinitis, conjunctivitis, and asthma predicts IgE sensitization in more than 25,000 Danes

Clinical and Translational Allergy, 2021
Background Allergic rhinitis (AR), allergic conjunctivitis (AC), and asthma composing multiple phenotypes and improved understanding of these phenotypes and their respective risk factors are needed.
Susan Mikkelsen, Khoa Manh Dinh, Jens Kjærgaard Boldsen, Ole Birger Pedersen, Gitte Juel Holst, Mikkel Steen Petersen, Kathrine Agergård Kaspersen, Bjarne Kuno Møller, Kaspar Rene Nielsen, Helene Martina Paarup, Klaus Rostgaard, Henrik Hjalgrim, Erik Sørensen, Linda Jenny Handgaard, Thomas Folkmann Hansen, Karina Banasik, Kristoffer Sølvsten Burgdorf, Henrik Ullum, Torben Sigsgaard, Christian Erikstrup   +19 more
doaj   +1 more source