Results 1 to 10 of about 30,446 (212)

The Edible Brown Seaweed Ecklonia cava Reduces Hypersensitivity in Postoperative and Neuropathic Pain Models in Rats

open access: yesMolecules, 2014
The current study was designed to investigate whether edible brown seaweed Ecklonia cava extracts exhibits analgesic effects in plantar incision and spared nerve injury (SNI) rats. To evaluate pain-related behavior, we performed the mechanical withdrawal
Jae Goo Kim   +4 more
doaj   +1 more source

Permanent relief from intermittent cold stress-induced fibromyalgia-like abnormal pain by repeated intrathecal administration of antidepressants

open access: yesMolecular Pain, 2011
Background Fibromyalgia (FM) is characterized by chronic widespread pain, which is often refractory to conventional painkillers. Numerous clinical studies have demonstrated that antidepressants are effective in treating FM pain. We previously established
Mukae Takehiro   +6 more
doaj   +1 more source

Bee Venom Acupuncture Attenuates Oxaliplatin-Induced Neuropathic Pain by Modulating Action Potential Threshold in A-Fiber Dorsal Root Ganglia Neurons

open access: yesToxins, 2020
Oxaliplatin is a third-generation platinum-based chemotherapeutic drug widely used in colorectal cancer treatment. Although potent against this tumor, it can induce cold and mechanical allodynia even after a single injection.
Ji Hwan Lee   +4 more
doaj   +1 more source

Clinical observation of the effect of prophylaxis on allodynia in patients with migraine

open access: yesJournal of Pain Research, 2018
Na Zhang,1 Chun-Fu Chen2 1Department of Emergency Medicine, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, China; 2Department of Neurology, Shandong Provincial Hospital, Shandong University, Jinan 250021, China Objective: The
Zhang N, Chen CF
doaj  

A case of phantom pain and stump pain that was effectively controlled by ultrasound‐guided ulnar and median peripheral nerve blocks

open access: yesClinical Case Reports, 2023
Phantom limb pain and stump pain are often intractable, and their incidences are relatively high. We report a case of a patient with phantom limb and stump pain of the finger, who was successfully treated by peripheral nerve blocks.
Shunya Sekiguchi   +4 more
doaj   +1 more source

The interaction of intrathecal neostigmine and N-cyclohexyladenosine on anti-allodynic effects in rats with a nerve ligation injury [PDF]

open access: yesKorean Journal of Anesthesiology, 2010
BackgroundNerve ligation injury in rats produces a pain syndrome that includes mechanical allodynia. Intrathecal administration of cholinesterase inhibitors or adenosine receptor agonists have anti-allodynic effects in this model.
Dae Kee Choi   +2 more
doaj   +1 more source

Beyond Pain Relief: Unveiling the Multifaceted Impact of Anti-CGRP/R mAbs on Comorbid Symptoms in Resistant Migraine Patients

open access: yesBiomedicines
The study aimed to evaluate the effects of monoclonal antibodies (mAbs) acting on the calcitonin gene-related peptide (CGRP) or its receptor (anti-CGRP/R mAbs) on migraine comorbidities of depression, anxiety, and fatigue in patients resistant to ...
Alessandra Della Vecchia   +7 more
doaj   +1 more source

RNA Sequencing Dataset of Drosophila Nociceptor Translatomic Response to Injury

open access: yesData
To prepare to address the mechanisms of injury-induced nociceptor sensitization, we sequenced the translatome of the nociceptors of injured Drosophila larvae and those of uninjured larvae.
Christine M. Hale   +6 more
doaj   +1 more source

Antiallodynic Effects of Bee Venom in an Animal Model of Complex Regional Pain Syndrome Type 1 (CRPS-I)

open access: yesToxins, 2017
Neuropathic pain in a chronic post-ischaemic pain (CPIP) model mimics the symptoms of complex regional pain syndrome type I (CRPS I). The administration of bee venom (BV) has been utilized in Eastern medicine to treat chronic inflammatory diseases ...
Sung Hyun Lee   +8 more
doaj   +1 more source

The analgesic effect of intravenous methylprednisolone on acute neuropathic pain with allodynia due to central cord syndrome: a retrospective study

open access: yesJournal of Pain Research, 2018
Liandong Li,1 Yawei Han,2 Tengshuai Li,1 Jiaming Zhou,1 Chao Sun,3,4 Yuan Xue1 1Department of Orthopaedics Surgery, Tianjin Medical University General Hospital, Tianjin, China; 2Department of Histology and Embryology, School of Basic Medical Sciences ...
Li L, Han Y, Li T, Zhou J, Sun C, Xue Y
doaj  

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