Results 1 to 10 of about 55,599 (275)

The Relationship Between the Presence of Allodynia and Pain Acceptance and Somatosensory Amplification in Patients with Migraine

open access: yesHaseki Tıp Bülteni, 2023
Aim:Allodynia is a pain disorder that adversely affects the prognosis of migraine and reduces the quality of life of patients with migraine. Thus, the study evaluated the relationship between the presence of allodynia and psychiatric aspects such as ...
Aysu Yakin Olgun   +3 more
doaj   +1 more source

Cutaneous allodynia as predictor for treatment response in chronic migraine: a cohort study

open access: yesThe Journal of Headache and Pain, 2023
Background Central sensitisation is an important mechanism in migraine chronification. It is presumed to occur in second and third order neurons sequentially, resulting in an analogous spatial distribution of cutaneous allodynia with cephalic and ...
Judith A. Pijpers   +4 more
doaj   +1 more source

Ultrasound-Guided combined greater occipital nerve block at the C2 level with trapezius trigger point injection and supraorbital-Supratrochlear nerve block: More effective on allodynia and disability in chronic migraine

open access: yesAnnals of Indian Academy of Neurology, 2023
Background: Chronic migraine (CM) patients with cutaneous allodynia (CA) show a poor response to treatment. Long-term studies have yet to be conducted to demonstrate the efficacy of blocks on CA.
Suna Aşkın Turan   +3 more
doaj   +1 more source

The Histamine H4 Receptor Participates in the Anti-Neuropathic Effect of the Adenosine A3 Receptor Agonist IB-MECA: Role of CD4+ T Cells

open access: yesBiomolecules, 2021
A3 adenosine receptor (A3AR) agonists have emerged as potent relievers of neuropathic pain by a T cell-mediated production of IL-10. The H4 histamine receptor (H4R), also implicated in pain modulation, is expressed on T cells playing a preeminent role in
Laura Micheli   +7 more
doaj   +1 more source

Kinin B2 Receptor Mediates Cisplatin-Induced Painful Peripheral Neuropathy by Intracellular Kinase Pathways and TRPA1 Channel Sensitisation

open access: yesPharmaceuticals, 2023
Chemotherapy-induced peripheral neuropathy is a severe clinical problem frequently associated with cisplatin use. Although its pathophysiology is poorly understood, it is known that kinin receptors and the transient receptor potential ankyrin 1 (TRPA1 ...
Gabriela Becker   +3 more
doaj   +1 more source

Vitamin D, Chronic Migraine, and Extracranial Pain: Is There a Link? Data From an Observational Study

open access: yesFrontiers in Neurology, 2021
Several studies focused on the role of vitamin D (vitD) in pain chronification. This study focused on vitD level and pain chronification and extension in headache disorders.
Valentina Rebecchi   +19 more
doaj   +1 more source

Nociceptive neuropeptide increases and periorbital allodynia in a model of traumatic brain injury. [PDF]

open access: yes, 2012
OBJECTIVE: This study tests the hypothesis that injury to the somatosensory cortex is associated with periorbital allodynia and increases in nociceptive neuropeptides in the brainstem in a mouse model of controlled cortical impact (CCI) injury.
Amenta, Peter S.   +4 more
core   +2 more sources

Pharmacological Differences Between Static and Dynamic Allodynia in Mice With Herpetic or Postherpetic Pain

open access: yesJournal of Pharmacological Sciences, 2008
In the present study, we investigated whether dynamic and static allodynia would be developed in the affected dermatome in murine models of herpetic pain and postherpetic neuralgia and pharmacologically characterized the allodynia.
Atsushi Sasaki   +5 more
doaj   +1 more source

Frequent mild head injury promotes trigeminal sensitivity concomitant with microglial proliferation, astrocytosis, and increased neuropeptide levels in the trigeminal pain system. [PDF]

open access: yes, 2017
BACKGROUND: Frequent mild head injuries or concussion along with the presence of headache may contribute to the persistence of concussion symptoms. METHODS: In this study, the acute effects of recovery between mild head injuries and the frequency of ...
Assari, Soroush   +4 more
core   +2 more sources

Favorable outcome of early treatment of new onset child and adolescent migraine-implications for disease modification. [PDF]

open access: yes, 2009
There is evidence that the prevalence of migraine in children and adolescents may be increasing. Current theories of migraine pathophysiology in adults suggest activation of central cortical and brainstem pathways in conjunction with the peripheral ...
A Ferrari   +52 more
core   +1 more source

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