Results 1 to 10 of about 66,158 (349)
Cutaneous allodynia as predictor for treatment response in chronic migraine: a cohort study
The Journal of Headache and Pain, 2023 Background Central sensitisation is an important mechanism in migraine chronification. It is presumed to occur in second and third order neurons sequentially, resulting in an analogous spatial distribution of cutaneous allodynia with cephalic and ...
Judith A. Pijpers +4 more
doaj +2 more sources
Cutaneous Allodynia in Migraine: A Narrative Review [PDF]
Frontiers in Neurology, 2022 Objective In the present work, we conduct a narrative review of the most relevant literature on cutaneous allodynia (CA) in migraine. Background CA is regarded as the perception of pain in response to non-noxious skin stimulation.
Ane Mínguez-Olaondo +8 more
semanticscholar +6 more sources
The Journal of Headache and Pain, 2019 Background OnabotulinumtoxinA is effective in treating chronic migraine (CM), but there are limited data assessing how allodynia affects preventive treatment responses.
William B. Young +6 more
doaj +2 more sources
Cephalalgia, 2023 Background Migraine is a complex neurological disorder involving generalized abnormalities in processing sensory information. Adopting evidence that central sensitization imposes major hurdles in the treatment of migraine, we hypothesized that it is the ...
S. Ashina +4 more
semanticscholar +1 more source
Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice
Nature Communications, 2022 Efficacy of monoclonal antibodies against calcitonin gene-related peptide (CGRP) or its receptor (calcitonin receptor-like receptor/receptor activity modifying protein-1, CLR/RAMP1) implicates peripherally-released CGRP in migraine pain.
Francesco De Logu +18 more
semanticscholar +1 more source
Molecular Pain, 2023 Mechanical allodynia can be evoked by punctate pressure contact with the skin (punctate mechanical allodynia) and dynamic contact stimulation induced by gentle touching of the skin (dynamic mechanical allodynia).
Zihan Hu +12 more
semanticscholar +1 more source
Haseki Tıp Bülteni, 2023 Aim:Allodynia is a pain disorder that adversely affects the prognosis of migraine and reduces the quality of life of patients with migraine. Thus, the study evaluated the relationship between the presence of allodynia and psychiatric aspects such as ...
Aysu Yakin Olgun +3 more
doaj +1 more source
Journal of Neuroinflammation, 2022 Neuroinflammation in spinal dorsal horn (SDH) plays an important role in the pathogenesis of interstitial cystitis/bladder pain syndrome (IC/BPS). Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) exert potent anti-inflammatory activities in
Chi Zhang +8 more
semanticscholar +1 more source
Silent cold-sensing neurons contribute to cold allodynia in neuropathic pain
Brain : a journal of neurology, 2021 Patients with neuropathic pain often experience innocuous cooling as excruciating pain. The cell and molecular basis of this cold allodynia is little understood.
Donald Iain MacDonald +5 more
semanticscholar +1 more source
Frontiers in Neurology, 2022 Purpose of the ReviewWe reviewed the studies of mechanical punctate pain thresholds (MPTs) in patients with migraine and summarized their findings focusing on the differences in MPT measurement and MPTs in different phases of migraine.MethodsWe searched ...
Li-Ling Hope Pan +4 more
doaj +1 more source