Results 121 to 130 of about 52,858 (307)
Where Does It All Itch? Exploring the Characteristics of Pruritus in Small Fiber Neuropathy
Journal of the Peripheral Nervous System, Volume 30, Issue 3, September 2025.ABSTRACT Background Chronic itch, or pruritus, is a common discomfort of the skin. Chronic itch has been described as a symptom of small fiber neuropathy (SFN), a disorder affecting the small myelinated Aδ‐ and unmyelinated C‐fibers. While prior studies report itch rates in SFN ranging from 63%–68%, a distinct pattern has not been identified.
Dennis Kool +3 more
wiley +1 more source
Development and initial validation of a sensory threshold examination protocol (STEP) for phenotyping canine pain syndromes [PDF]
, 2017 Objective To study feasibility and test-retest repeatability of a sensory threshold examination protocol (STEP) and report quantitative sensory threshold distributions in healthy dogs.
Abeyesinghe, S M +5 more
core +1 more source
Postherpetic Neuralgia: Irritable Nociceptors and Deafferentation
Neurobiology of Disease, 1998 Postherpetic neuralgia (PHN) is a common and often devastatingly painful condition. It is also one of the most extensively investigated of the neuropathic pains. Patients with PHN have been studied using quantitative testing of primary afferent function,
Howard L. Fields +2 more
doaj
European Journal of Pain, Volume 29, Issue 6, July 2025.ABSTRACT Background Pain is one of the most prevalent health issues in Europe, yet the quality of pain education for healthcare professionals remains unclear. This study assessed the status of undergraduate and postgraduate pain education for nurses, physicians, psychologists, and physiotherapists across Europe, identifying key strategies to enhance ...
Nathan Skidmore +9 more
wiley +1 more source
Evaluation of behavior in transgenic mouse models to understand human congenital pain conditions [PDF]
, 2018 BACKGROUND: Containing a brain for signal processing and decision making, and a peripheral component for sensation and response, the nervous system provides higher organisms a powerful method of interacting with their environment.
Bullock, Daniel
core
Apoptotic gene expression in neuropathic pain [PDF]
, 2008 Pain initiated or caused by a primary lesion or dysfunction in the nervous system is defined as neuropathic pain. It results from direct injury to nerves in the peripheral or central nervous system and is associated with several clinical symptoms ...
Annalucia Migliozzi +6 more
core +2 more sources
Synergistic Effect between Intrathecal Non-NMDA Antagonist and Gabapentin on Allodynia Induced by Spinal Nerve Ligation in Rats [PDF]
, 2000 Shao-Rui Chen +3 more
openalex +1 more source
Neuropathic Pain in Nursing Homes
European Journal of Pain, Volume 29, Issue 6, July 2025.ABSTRACT Background In older persons, pain prevalence is estimated to range between 22% and 80%. In nursing home residents, underevaluated pain is common despite pain management quality indicators. This study aims to assess neuropathic pain (NP) prevalence, NP evaluation and treatment, and healthcare professionals’ practices and needs to optimise NP ...
Gisèle Pickering +6 more
wiley +1 more source
The role of cGMP and PKG-I in spinal nociceptive processing [PDF]
, 2005 First paragraph (this article has no abstract) Persistent stimulation of nociceptors results in sensitization of nociceptive sensory neurons, which is associated with hyperalgesia and allodynia.
Geisslinger, Gerd +5 more
core +1 more source
European Journal of Pain, Volume 29, Issue 6, July 2025.ABSTRACT Background Spinal cord injury (SCI) leads to persistent inflammation, contributing to chronic neuropathic pain. However, current treatments show limited efficacy. Three types of nitric oxide synthase (NOS) play different roles in inflammation and neuronal hyperexcitation.
Youngkyung Kim +2 more
wiley +1 more source