ACR Open Rheumatology, Volume 7, Issue 11, November 2025.Objective To identify predictors of reduced risk for neuropathic pain (NP) one year after total knee arthroplasty (TKA) among patients who did not report NP before surgery. Methods We included primary TKAs performed between January 1, 2014, and June 30, 2022. NP was defined as Douleur Neuropathique en 4 Questions scores ≥4 before and one year after TKA.
Hermes H. Miozzari +5 more
wiley +1 more source
European Journal of Pain, Volume 29, Issue 10, November 2025.ABSTRACT Background There is limited real‐world evidence on predictive factors for good outcomes in patients with chronic neuropathic pain (NP) treated in multidisciplinary tertiary care centres. This study aimed to identify subgroups of NP patients with similar pain trajectories and evaluate associated factors.
Xavier Moisset +3 more
wiley +1 more source
Local inhibitory effects of dynorphin A-(1–17) on capsaicin-induced thermal allodynia in rhesus monkeys [PDF]
, 2000 Mei‐Chuan Ko +4 more
openalex +1 more source
Phenotyping Chronic Pain and Neuropathic Pain in Population Studies
European Journal of Pain, Volume 29, Issue 10, November 2025.ABSTRACT Background and Objective Chronic pain is a major global health challenge with substantial individual and societal burden. Epidemiological studies are essential for understanding the scale of the problem and identifying approaches to management.
Ian‐Ju Liang +2 more
wiley +1 more source
Synergistic Effect between Intrathecal Non-NMDA Antagonist and Gabapentin on Allodynia Induced by Spinal Nerve Ligation in Rats [PDF]
, 2000 Shao-Rui Chen +3 more
openalex +1 more source
Perturbations in neuroinflammatory pathways are associated with paclitaxel-induced peripheral neuropathy in breast cancer survivors. [PDF]
, 2019 Paclitaxel is a common chemotherapy drug associated with the development of chronic paclitaxel-induced peripheral neuropathy (PIPN). PIPN is associated with neuroinflammatory mechanisms in pre-clinical studies.
Abrams, Gary +9 more
core
Developing the FIGO‐IPPS “R U MOVVING SOMe” classification system for female chronic pelvic pain
International Journal of Gynecology &Obstetrics, Volume 171, Issue 2, Page 550-565, November 2025.Abstract The goal was to develop a pragmatic classification system for conditions associated with chronic pelvic pain (CPP), aiming to enhance diagnosis, management, education, and research of CPP. An international, multidisciplinary panel participated in a modified RAND/UCLA Delphi consensus.
Georgine Lamvu +8 more
wiley +1 more source
The development of cutaneous allodynia during a migraine attack Clinical evidence for the sequential recruitment of spinal and supraspinal nociceptive neurons in migraine [PDF]
, 2000 Rami Burstein
openalex +1 more source
The effect of environment on post surgical overall well-being and pain sensitivity in an animal model [PDF]
, 2016 With chronic post surgical pain affecting up to one third of patients undergoing surgeries and the price of treatment being astoundingly high there has been a transition in research to investigate and identify risk factors. Through identification of risk
Reddy, Archana
core +1 more source
Anti‐nociceptive action of leonurine through TRPA1 and TRPV4 channels modulation
British Journal of Pharmacology, Volume 182, Issue 22, Page 5469-5488, November 2025.Background and Purpose Leonurine, a pseudoalkaloid derived from Leonotis leonurus, has been traditionally used in herbal medicine to alleviate conditions such as headaches and abdominal discomfort. Its therapeutic effects are often attributed to potential antioxidant properties; however, the precise molecular mechanisms remain poorly understood ...
Matilde Marini +20 more
wiley +1 more source