Allogeneic hematopoietic stem cell transplantation in Tunisia [PDF]
In 1998, the Tunisian team of the 'Centre National de Greffe de Moelle Osseuse' initiated allogeneic hematopoietic SCT (AHSCT) in Tunisia. As of June 2007, information was collected about 299 patients with a first AHSCT and 12 additional retransplants. The median age was 19 years (range 2-49 years). The main indications were aplastic anemia (n=106, 36%)
T, Ben Othman +7 more
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Renal dysfunction in allogeneic hematopoietic cell transplantation [PDF]
Allogeneic hematopoietic cell transplantation (HCT), formerly called bone marrow transplantation, can potentially cure various malignant and non-malignant diseases, but it is associated with a high risk of toxicity. We have previously shown an overall 21% incidence of severe acute renal failure in patients undergoing autologous HCT.
Parikh, Chirag R. +10 more
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Quantitative and qualitative differences in use and trends of hematopoietic stem cell transplantation: a global observational study [PDF]
Fifty-five years after publication of the first hematopoietic stem cell transplantation this technique has become an accepted treatment option for defined hematologic and non-hematologic disorders.
Madrigal, Alejandro +31 more
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Allogeneic Hematopoietic Cell Transplantation in the Outpatient Setting [PDF]
Conditioning with fludarabine and low-dose total-body irradiation before allogeneic hematopoietic cell transplantation (HCT) enabled treating older or medically infirm patients with advanced hematologic malignancies in the outpatient setting. Between December 1997 and June 2017, 1037 patients with hematologic malignancies received peripheral blood stem
Noa Granot +5 more
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Hematopoietic chimerism after allogeneic stem cell transplantation : a comparison of quantitative analysis by automated DNA sizing and fluorescent in situ hybridization [PDF]
Background: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is performed mainly in patients with high-risk or advanced hematologic malignancies and congenital or acquired aplastic anemias.
Wachowiak, Jacek +13 more
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Allogeneic Hematopoietic Cell Transplantation in Septuagenarians [PDF]
Acute myelogenous leukemia (AML) and myelodysplastic syndrome (MDS) are diseases that affect predominantly older adults, and it is precisely this group of patients that continues to suffer from particularly poor outcomes [1-4]. Although hematopoietic cell transplantation (HCT) has emerged as an important treatment strategy for patients with high-risk ...
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Immunotherapy of invasive fungal infection in hematopoietic stem cell transplant recipients [PDF]
Despite the availability of new antifungal compounds, invasive fungal infection remains a significant cause of morbidity and mortality in children and adults undergoing allogeneic hematopoietic stem cell transplantation (HSCT). Allogeneic HSCT recipients
Lehrnbecher, Thomas +11 more
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Allogeneic hematopoietic cell transplantation to treat two synchronous hematologic malignancies
Allogeneic hematopoietic cell transplantation often represents the only solution for several poor-prognosis hematologic malignancies. The curative strategy for patients with synchronous hematologic disorders is always difficult and, in most cases ...
Enrico Santinelli* +17 more
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Sequential anti-cytomegalovirus response monitoring may allow prediction of cytomegalovirus reactivation after allogeneic stem cell transplantation [PDF]
Background: Reconstitution of cytomegalovirus-specific CD3+CD8+ T cells (CMV-CTLs) after allogeneic hematopoietic stem cell transplantation (HSCT) is necessary to bring cytomegalovirus (CMV) reactivation under control. However, the parameters determining
Matthias Eder (21135) +74 more
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Outcomes after alemtuzumab-containing reduced-intensity allogeneic transplantation regimen for relapsed and refractory non-Hodgkin lymphoma [PDF]
We report the outcomes after reduced-intensity conditioning allogeneic stem cell transplantation (RIT) for non-Hodgkin lymphoma (NHL) in 88 patients (low-grade NHL [LG-NHL], n = 41; high-grade NHL [HG-NHL], n = 37; mantle cell lymphoma [MCL], n = 10 ...
Mahendra, P +37 more
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