Molecular monitoring of minimal residual disease in two patients with MLL-rearranged acute myeloid leukemia and haploidentical transplantation after relapse [PDF]
This report describes the clinical courses of two acute myeloid leukemia patients. Both had MLL translocations, the first a t(10;11)(p11.2;q23) with MLL-AF10 and the second a t(11;19)(q23;p13.1) with MLL-ELL fusion.
Meyer, Claus +23 more
core +1 more source
Allogeneic hematopoietic cell transplantation for multiple myeloma
At the present time, allogeneic hematopoetic stem cell transplantation (AHSCT) is the only proven treatment for multiple myeloma (MM) that is potentially curative. This conclusion is based on observations of patients who have undergone AHSCT and are living disease-free for 5-15 years. While patients who receive either allogeneic or autologous stem cell
openaire +2 more sources
Advances in allogeneic hematopoietic cell transplantation for sickle cell disease have improved outcomes, but there is limited analysis of healthcare utilization in this setting.
Staci D. Arnold +44 more
doaj +1 more source
Clinical and biochemical improvements in a patient with MNGIE following enzyme replacement. [PDF]
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a rare autosomal recessive metabolic disorder caused by a deficiency of thymidine phosphorylase (TP, EC2.4.2.4) due to mutations in the nuclear gene TYMP.
Bax, BE +13 more
core +1 more source
Cytotoxic Pathways in Allogeneic Hematopoietic Cell Transplantation
Allogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative treatment for hematologic malignancies, and other hematologic and immunologic diseases. Donor-derived immune cells identify and attack cancer cells in the patient producing a unique graft-vs.-tumor (GVT) effect.
Wei Du, Xuefang Cao, Xuefang Cao
openaire +3 more sources
Decreased HIV diversity after allogeneic stem cell transplantation of an HIV-1 infected patient : a case report [PDF]
The human immunodeficiency virus type 1 (HIV-1) coreceptor use and viral evolution were analyzed in blood samples from an HIV-1 infected patient undergoing allogeneic stem cell transplantation (SCT).
Bravo Ignacio G +39 more
core +1 more source
Microbiome Anomalies in Allogeneic Hematopoietic Cell Transplantation
The microbiome is an integrated part of the human body that can modulate a variety of disease processes and affect prognosis, treatment response, complications, and outcomes. The importance of allogeneic hematopoietic cell transplantation in cancer treatment has resulted in extensive investigations on the interaction between the microbiome and this ...
Zaker I, Schwabkey, Robert R, Jenq
openaire +3 more sources
Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection [PDF]
Background: There is currently no effective AIDS vaccine, emphasizing the importance of developing alternative therapies. Recently, a patient was successfully transplanted with allogeneic, naturally resistant CCR5-negative (CCR5 delta 32) cells, setting ...
Trobridge, Grant D. +28 more
core +2 more sources
Risk factors for tuberculosis in patients after allogeneic hematopoietic stem cell transplantation.
Risk factors for tuberculosis in patients after allogeneic hematopoietic stem cell transplantation.
Dong-Gun Lee (3826297) +18 more
core +1 more source
Allogeneic hematopoietic cell transplantation in mantle cell lymphoma [PDF]
Mantle cell lymphoma (MCL) is a high-risk non-Hodgkin lymphoma that is considered incurable with standard chemotherapy. While autologous hematopoietic cell transplantation (autoHCT) can provide lengthy disease-free survival in select patients, cure generally is not an expected outcome with this approach.
Ryan D, Cassaday, Ajay K, Gopal
openaire +2 more sources

