Results 1 to 10 of about 256,813 (405)

Allogeneic Hematopoietic Stem Cell Transplantation

Therapeutic Apheresis and Dialysis, 2003
Abstract: More than 30 years have passed since the first clinical application of allogeneic bone marrow transplantation to treat hematological diseases. In recent years, the availability of peripheral blood and cord blood as additional sources of stem cells other than bone marrow has expanded the applicability of hematopoietic stem cell transplantation.
Shunro Kai, Hiroshi Hara
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Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation [PDF]

Journal of Hematotherapy & Stem Cell Research, 2002
Allogeneic hematopoietic stem cell transplantation (HSCT) is the most effective treatment for selected hematological malignancies. Its curative potential is largely mediated by an immune-mediated destruction of malignant cells by donor lymphocytes termed graft-versus-leukemia (GVL) effect.
Frédéric Baron, Yves Béguin
openalex   +4 more sources

In Silico Derivation of HLA-Specific Alloreactivity Potential from Whole Exome Sequencing of Stem Cell Transplant Donors and Recipients: Understanding the Quantitative Immuno-biology of Allogeneic Transplantation [PDF]

Frontiers in Immunology 2014. 5:529, 2014
Donor T cell mediated graft vs. host effects may result from the aggregate alloreactivity to minor histocompatibility antigens (mHA) presented by the HLA in each donor-recipient pair (DRP) undergoing stem cell transplantation (SCT). Whole exome sequencing has demonstrated extensive nucleotide sequence variation in HLA-matched DRP. Non-synonymous single
Batalo, Michael, Buck, Gregory A., Griffith, Phil, Hess, Michael L., Jameson-Lee, Max, Khalid, Haniya, Koparde, Vishal, Manjili, Masoud H., Neale, Michael C., Roberts, Catherine H., Sampson, Juliana K., Scalora, Allison F., Serrano, Myrna G., Sheth, Nihar U., Toor, Amir A.   +14 more
arxiv   +8 more sources

Allogeneic hematopoietic stem cell transplantation for T-cell lymphomas [PDF]

Blood, 2018
AbstractMature T- and natural killer (NK)–cell neoplasms comprise a group of morphologically, immunophenotypically, molecularly, and clinically heterogeneous disorders with generally unfavorable outcome. Results of first-line chemotherapy are unsatisfactory for the most common T-cell lymphomas (peripheral T-cell lymphoma, not otherwise specified ...
Norbert Schmitz, Georg Lenz, Matthias Stelljes   +2 more
openaire   +4 more sources

Allogeneic Hematopoietic Stem Cell Transplantation in Myelofibrosis [PDF]

Клиническая онкогематология, 2016
Background & Aims. At present, the allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only treatment option with curative potential in patients with myelofibrosis (MF), especially in intermediate and high risk categories.
MV Barabanshchikova, EV Morozova, VV Baikov, IM Barkhatov, NN Mamaev, SN Bondarenko, , AL Alyanskii, LS Zubarovskaya, BV Afanas’ev   +8 more
doaj   +3 more sources

Allogeneic hematopoietic stem cell transplantation in mycosis fungoides [PDF]

Anais Brasileiros de Dermatologia, 2013
Mycosis Fungoides is typically an indolent disease in early stages. However, approximately 30% of patients have advanced staged disease at presentation and 20% will develop it at some time. These patients have a poorer prognosis with a median survival of
Angelo Atalla, Abrahão Elias Hallack Neto, Denise Bittencourt Siqueira, Gabriela Cumani Toledo   +3 more
doaj   +6 more sources

Nonmyeloablative therapy and allogeneic hematopoietic stem cell transplantation [PDF]

Experimental Hematology, 2003
The toxicities associated with conventional myeloablative therapy and allogeneic hematopoietic stem cell transplantation (SCT) limit the use of this potentially curative approach to relatively healthy young patients. The risk of treatment-related morbidity and mortality with conventional allogeneic SCT ranges from 10% to 50%, depending on the age of ...
Imad A. Tabbara, Richard M. Ingram
openalex   +3 more sources

Successful bone marrow transplantation in a patient with Diamond-Blackfan anemia with co-existing Duchenne muscular dystrophy: a case report [PDF]

Journal of Medical Case Reports, 2011
Introduction Diamond-Blackfan anemia and Duchenne muscular dystrophy are two rare congenital anomalies. Both anomalies occurring in the same child is extremely rare.
Kaur Jasmeet, Sharma Sanjeevan, Sharma Ajay, Das Satyaranjan, Nair Velu, Mishra DK   +5 more
doaj   +4 more sources

Allogeneic hematopoietic stem-cell transplantation for myelofibrosis [PDF]

Therapeutic Advances in Hematology, 2020
Myelofibrosis is one of the Philadelphia chromosome (Ph)-negative myeloproliferative neoplasms with heterogeneous clinical course. Though many treatment options, including Janus kinase (JAK) inhibitors, have provided clinical benefits and improved survival, allogeneic hematopoietic stem-cell transplantation (AHSCT) remains the only potentially ...
Lining Zhang, Fan Yang, Sizhou Feng
openaire   +4 more sources

In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

Nature Network Boston, 2023
The recipient of an allogeneic stem cell transplant from a CCR5Δ32/Δ32 donor shows evidence of HIV type 1 cure, including the absence of a viral rebound over 4 years after stopping antiretroviral treatment.
B. Jensen, E. Knops, Leon Cords, N. Lübke, M. Salgado, K. Busman-Sahay, J. Estes, Laura E. P. Huyveneers, F. Perdomo-Celis, Melanie Wittner, C. Gálvez, Christiane Mummert, C. Passaes, J. Eberhard, C. Münk, I. Hauber, J. Hauber, E. Heger, J. De Clercq, L. Vandekerckhove, S. Bergmann, G. Dunay, F. Klein, D. Häussinger, Johannes C Fischer, K. Nachtkamp, J. Timm, R. Kaiser, T. Harrer, T. Luedde, M. Nijhuis, A. Sáez-Cirión, J. Schulze zur Wiesch, A. Wensing, J. Martinez-Picado, G. Kobbe   +35 more
semanticscholar   +1 more source