Results 51 to 60 of about 16,837 (286)
Incidence of alloimunization in sickle cell disease: experience of a center in São Paulo [PDF]
Einstein (São Paulo), 2011 Objective: To identify the incidence of alloimmunization in sicklecell disease patients, as well as autoantibodies and the phenotypicprofile of these patients for the following erythrocyte antigengroups: Rh, Kell, Kidd, Duffy and MNS.
Ricardo Helman +2 more
doaj +4 more sources
Kell alloimmunization in pregnancy: Lessons to be learnt
Global Journal of Transfusion Medicine, 2017 With the introduction of anti-D prophylaxis, the incidence of RhD alloimmunization in pregnancy has been significantly reduced. RhD remains the most common cause of hemolytic disease of fetus and newborn (HDFN).
Rajeswari Subramaniyan
doaj +1 more source
eJHaem, 2021 Patients with sickle cell disease (SCD) have a high prevalence of RBC alloimmunization. However, underlying mechanisms are poorly understood. Given that proinflammatory type 1 interferons (IFNα/β) and interferon stimulated genes (ISGs) promote ...
Emaan Madany +10 more
doaj +1 more source
The rejection that defies anti-rejection drugs. Chronic vascular rejection (allograft vasculopathy): The role of terminology and linguistic relativity [PDF]
arXiv, 2023 Solid organ transplantation has by now become a common medical procedure. Owing to the introduction of new immunosuppressive drugs, the allograft loss due to acute rejection has been reduced significantly over time. Tragically, the number of donor organs lost due to allograft vasculopathy (AV), generally named chronic vascular rejection or chronic ...
arxiv
Molecular studies reveal a concordant KEL genotyping between patients with hemoglobinopathies and blood donors in São Paulo City, Brazil [PDF]
, 2008 Universidade Federal de São Paulo, Discipline Hematol & Transfus Med, BR-04023092 São Paulo, BrazilUniversidade Federal de São Paulo, Discipline Hematol & Transfus Med, BR-04023092 São Paulo, BrazilWeb of ...
Bordin, Jose Orlando +4 more
core +1 more source
Alloimmune T cells in transplantation [PDF]
Journal of Clinical Investigation, 2017 Alloimmune T cells are central mediators of rejection and graft-versus-host disease in both solid organ and hematopoietic stem cell transplantation. Unique among immune responses in terms of its strength and diversity, the T cell alloresponse reflects extensive genetic polymorphisms between allogeneic donors and recipients, most prominently within the ...
Megan Sykes, Susan DeWolf
openaire +3 more sources
Alloimmunization in multitransfused liver disease patients: Impact of underlying disease
Asian Journal of Transfusion Science, 2016 Introduction: Transfusion support is vital to the management of patients with liver diseases. Repeated transfusions are associated with many risks such as transfusion-transmitted infection, transfusion immunomodulation, and alloimmunization.
Meenu Bajpai +2 more
doaj +1 more source
Current status of alloimmunity [PDF]
Current Opinion in Nephrology and Hypertension, 2016 The present review aims to highlight the major recent advances in transplantation with regards to basic, translational, and clinical research.We describe new concepts in understanding allorecognition and allospecificity of T cells, and discuss current challenges in targeting memory T cells, including the limitation of rodent disease models.
Naoka Murakami +2 more
openaire +3 more sources
Delayed hemolytic transfusion reaction presenting as a painful crisis in a patient with sickle cell anemia [PDF]
, 1999 CONTEXT: Patients with sickle cell anemia (SCA) are frequently transfused with red blood cells (RBC). Recently, we reported that the calculated risk of RBC alloimmunization per transfused unit in Brazilian patients with SCA is 1.15%.
Bordin, Jose Orlando +2 more
core +2 more sources
Alloantigen-based AIDS vaccine: revisiting a "rightfully" discarded promising strategy. [PDF]
, 2011 This report revisits the accidental discovery that protection against simian immunodeficiency virus (SIV) infection in the early successful experimental AIDS vaccine studies in Rhesus macaques was due to antibodies directed against human leukocyte ...
Boasso, A, Shearer, GM
core +3 more sources