ABSTRACT Background Central venous catheters (CVCs) are essential in pediatric hematology‐oncology, for the administration of chemotherapy and supportive therapy. Thrombocytopenia increases the risk of bleeding and current guidelines recommend prophylactic platelet transfusions below 40–50 × 109/L, though evidence is limited and transfusions entail ...
Alessandro Raffaele +8 more
wiley +1 more source
Delayed hemolytic transfusion reaction presenting as a painful crisis in a patient with sickle cell anemia [PDF]
CONTEXT: Patients with sickle cell anemia (SCA) are frequently transfused with red blood cells (RBC). Recently, we reported that the calculated risk of RBC alloimmunization per transfused unit in Brazilian patients with SCA is 1.15%.
Bordin, Jose Orlando +2 more
core +2 more sources
Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley +1 more source
Trends of Erythrocyte Alloimmunization in Transfused Women
Objective: To identify the trends of red cell alloimmunization in multi-transfused females using red blood cell panels. Study design: Cross-sectional study.
Sunia Ghaffar +5 more
doaj +1 more source
Evaluation of the New Lateral Flow Card MDmulticard® Basic Extended Phenotype in Routine Clinical Practice [PDF]
Background: Transfusion emergencies and critical situations require specifically designed devices to simplify and optimize the standard procedures. In addition, matching antigens over and above ABO-Rh-K would be beneficial. Methods: Routine blood samples
Candela-García, María-José +5 more
core +1 more source
Automated quantitative evaluation of fetal atrioventricular annular plane systolic excursion before and after intrauterine blood transfusion in pregnancies affected by red blood cell alloimmunization [PDF]
Aikaterini Zamprakou +5 more
openalex +1 more source
ABSTRACT Background Estimating the causal effect of third‐stage management approaches on preventing postpartum haemorrhage (PPH) in the context of physiologic birth using observational data requires conditioning on specific variables, with selection relying on assumptions about their roles in the exposure‐outcome pathway that are rarely made explicit ...
Vanessa Hébert +4 more
wiley +1 more source
Background: Non-Rhesus D antigen non-ABO, minor blood group alloimmunization in pregnant women is being increasingly recognized as a significant contributor to the development of the hemolytic disease of the fetus and newborn (HDFN).
Shrutiprajna Kar +3 more
doaj +1 more source
Alloantigen-based AIDS vaccine: revisiting a "rightfully" discarded promising strategy. [PDF]
This report revisits the accidental discovery that protection against simian immunodeficiency virus (SIV) infection in the early successful experimental AIDS vaccine studies in Rhesus macaques was due to antibodies directed against human leukocyte ...
Boasso, A, Shearer, GM
core +3 more sources
Not as “D”eadly as once thought – the risk of D-alloimmunization and hemolytic disease of the fetus and newborn following RhD-positive transfusion in trauma [PDF]
Mark H. Yazer +7 more
openalex +1 more source

