Results 81 to 90 of about 10,309 (223)
Transfusion, EarlyView.Abstract Background Patients with chronic transfusion needs such as those with sickle cell disease face a high risk of developing antibodies against high‐prevalence antigens in the RH blood group system, complicating transfusion therapy and potentially necessitating stem cell transplantation.
Rebekka Waldmann +9 more
wiley +1 more source
Frequency of Red Blood Cell Alloimmunization in Patients with Sickle Cell Disease in Palestine
Advances in Hematology, 2018 Background. Transfusion of red blood cells (RBC) is an essential therapeutic tool in sickle cell disease (SCD). Repeated RBC transfusions can cause alloimmunization which causes difficulty in cross-matching and finding compatible blood for transfusions ...
Fekri Samarah +3 more
doaj +1 more source
Transfusion, EarlyView.Abstract Background Red blood cell (RBC) transfusions are part of essential supportive therapy in patients with acute leukemia, where patients often present with anemia and thrombocytopenia. Together these cytopenias increase bleeding risk; however, optimal hemoglobin (Hb) thresholds for RBC transfusion remain undefined, and current recommendations for
Dimpy Modi +8 more
wiley +1 more source
Genetic diversity in RHD and RHCE genes among a selected Kenyan blood donor population
Transfusion, EarlyView.Abstract Background Serologic typing for ABO and RhD is standard in transfusion services, with extended serology and genotyping performed to reduce red cell alloimmunization risk. In Kenya, RH typing is limited to RhD, and genotyping is unavailable. This study used RHD/RHCE genotyping to predict phenotypes and their distribution in a Kenyan blood donor
Sandra A. Sowah +8 more
wiley +1 more source
Asian Journal of Transfusion Science, 2015 Objective: This study is aimed to determine the prevalence of alloimmunization due to antibodies to red blood cell (RBC) antigens (other than rhesus [Rh] antigen) and report the maternal, perinatal, and neonatal outcomes.
Tamima Al-Dughaishi +4 more
doaj +1 more source
Intraoperative blood transfusion requirements and deficient hemostasis in highly alloimmunized patients undergoing liver transplantation [PDF]
, 1988 During orthopic liver transplantation (OLT) a large transfusion of different blood components is frequently necessary. From 1981 to 1985 at the University Health Center in Pittsburgh, 4,318 units of RBCs and 4,788 units of platelets were administered ...
Duquesnoy, RJ +5 more
core
Transfusion, EarlyView.Abstract Background A minority of blood donors are Rh(D)‐negative, and Rh(D)‐negative red blood cell (RBC) products are often overutilized. As such, Rh(D)‐negative RBCs may be difficult to maintain in blood bank inventory. Study Design and Methods We changed our blood bank laboratory policy to approve non‐alloimmunized Rh(D)‐negative patients to ...
Julie Katz Karp +5 more
wiley +1 more source
A review of evidence on non-invasive prenatal diagnosis (NIPD) : tests for fetal RHD genotype [PDF]
, 2007 This report concentrates on three main areas. First and foremost, we set the background context for RhD NIPD in prenatal care. While the methodology chapter describes how the literature review was carried out and how additional information was collected,
Clay, Diane +5 more
core
Rare antigen‐negative red blood cells from pluripotent stem cells for precision transfusion medicine
Transfusion, EarlyView.Abstract Background Blood bank identification of antibodies against high‐prevalence antigens remains a challenge due to the scarcity of antigen‐negative reagent red cells sourced from blood donors. The MAM antigen, encoded by EMP3, is one such antigen associated with red cell alloimmunization and hemolytic disease of the fetus and newborn. Study Design
Naomi Gunawardena +9 more
wiley +1 more source