Results 81 to 90 of about 14,033 (212)

Alloimmunization to Rh Antigen (D, C, E, C, E) Among Pregnant Women Attending Antenatal Care in South Western Uganda

Journal of Blood Medicine, 2022
Yona Mbalibulha,1 Bernard Natukunda,1 Andrew Livex Okwi,2 Joan N Kalyango,3 Kajja Isaac,4 Sam Ononge5 1Department of Medical Laboratory Science, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda; 2Department of Pathology,
Mbalibulha Y, Natukunda B, Okwi AL, Kalyango JN, Isaac K, Ononge S   +5 more
doaj  

Maternal and perinatal outcomes associated with prophylactic erythrocytapheresis in pregnant women with sickle cell disease

International Journal of Gynecology &Obstetrics, EarlyView.
Pedro Junqueira Fleury Silva, Giovanna Santos Pinto Coelho, Luana de Jesus Pires, Camila Olivares Figueira, José Paulo de Siqueira Guida, Fernanda G. Surita, Juliana da‐Costa‐Santos, Bruno Deltreggia Benites, Paula de Melo Campos, Simone Cristina Olenscki Gilli, Sara T. O. Saad, Fernando F. Costa, Maria Laura Costa   +12 more
wiley   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

A study of red blood cell alloimmunization and autoimmunization among 200 multitransfused Egyptian β thalassemia patients

Scientific Reports, 2020
The development of hemolytic erythrocyte alloantibodies and autoantibodies complicates transfusion therapy in thalassemia patients. These antibodies ultimately increase the need for blood and intensify transfusion complications. There is a scanty data on
A. El-Beshlawy, Alshymaa Ahmed Salama, Mohamed Roshdy El Masry, Noha M. El Husseiny, Asmaa M. Abdelhameed   +4 more
semanticscholar   +1 more source

Functional validation of a modified platelet desialylation test for immune and hereditary thrombocytopenias

Transfusion Medicine, EarlyView.
Abstract Background Thrombocytopenia arises from heterogeneous inherited and acquired disorders, and identifying the underlying platelet clearance mechanisms remains challenging. Platelet desialylation, characterised by loss of sialic acid and consequent exposure of terminal β‐galactose residues recognised by the Ashwell–Morell receptor, represents an ...
Karen Nogueira Chinoca Ziza, Thamy Caroline Silva, Mateus Domentino, Marina Cavalcanti Albuquerque Veiga Conrado, João Vitor Bernardo Oliveira, Felipe Augusto Rós, Caroline Gabe, Elyse Moritz, Akemi Chiba, Paula Villaça, Vanderson Rocha, Alfredo Mendrone‐Junior, José Bordin, Dante Langhi, Carla Luana Dinardo   +14 more
wiley   +1 more source

Impact of alloimmunization on transfusion-dependent patient

, 2017
Red blood cell (RBC) alloimmunization can be a life-threatening complication for patients with thalassemia major and sickle cell disease (SCD) who must receive chronic therapeutic transfusions.
Surapon Tangvarasittichai*, Tangvarasittichai S   +1 more
core   +1 more source

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

Transfusion, EarlyView.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike, Albert Bondt, Douwe Schulte, Rien Leuvenink, Dirk Jan Mons, Peter C. Ligthart, E. Joanne T. Verweij, AFRICARhE Consortium, Enrico Lopriore, E. J. T. Joanne Verweij, Tienke Vermeiden, Thomas van den Akker, C. Ellen van der Schoot, Derek P. de Winter, Renske van Oever, Abera Kenay Tura, Tadesse Gure, Assefa Desalew, Tewodros Tesfa, Konjit Eshetu, Jeremia Pyuza, Rafiki N. Mjema, Priscus John Mapendo, Jeremiah John Hhera, Bariki Mchome, Patricia Swai, Blandina T. Mmbaga, Aisa Shayo, Peter Moons, Kondwani Kawaza, Luis Gadama, Albert J. R. Heck, C. Ellen van der Schoot, Gestur Vidarsson   +33 more
wiley   +1 more source

Investigating the molecular basis of the serological Rh D‐negative phenotype in Indonesia: nature, frequency, and impact for diagnostics

Transfusion, EarlyView.
Abstract Background Although widely studied and reported for more than 30 years, the molecular basis of Rh D‐negativity has remained unexplored in several regions of the world, including in Indonesia, Southeast Asia. Study Design and Methods A subset of 436 Indonesian blood donors originally typed D‐negative (D–) by routine serological testing was ...
Tonny Wongso, Teguh Triyono, Caroline Bénech, Gauthier Thomas, Sasi Widuri, Martono Adi Triyogo, Ni Kadek Mulyantari, Misnah Syarifuddin, Halimi Maksum, Winda Astuti Taruno, Hasna Fadlilatul Bidayah, Yann Fichou   +11 more
wiley   +1 more source

Massive fetomaternal hemorrhage and successful prevention of maternal RhD alloimmunization: A case report

Transfusion, EarlyView.
Abstract Background Massive fetomaternal hemorrhage can lead to significant fetal morbidity or mortality. RhD negative patients require appropriate treatment to prevent alloimmunization in subsequent pregnancies. Few cases with follow‐up into future pregnancies have been reported.
Sajjad Hassan, Angela Essa, Lauren Orr, Corina N. Schoen, Chester Andrzejewski   +4 more
wiley   +1 more source

Erythrocyte Alloimmunization and Transfusion Strategies in Sickle Cell Disease: A Single-Center Analysis [PDF]

Abdulaziz Yusuf,1,2 Abrar Ahmad,1 Hesham A El-Beshbishy,3 Heba Badie Gong,3 Chahed Walid Chahdah,3 Tahani Bakhsh4 1Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia; 2Blood Bank Department, Dr. Soliman Fakeeh
Ahmad A, El-Beshbishy HA, Yusuf A, Gong HB, Bakhsh T, Chahdah CW   +5 more
core