Results 71 to 80 of about 26,198 (235)

Towards a cure for gout: A two‑stage treat‐to‐target strategy from inflammation control to structural remission

Rheumatology &Autoimmunity, EarlyView.
Jiani Liu, Ziwen Xu, Wenxi Cui, Man Lu, Qingqing Zhang, Wenxia Lin, Shixian Chen, Weikai Lin, Guichuan Lai, Meng Li, Juan Li   +10 more
wiley   +1 more source

The Safety of Treating Women With Inflammatory Bowel Disease With Allopurinol and Low‐Dose Thiopurine During Pregnancy: A Single‐Center Experience

JCC Plus, Volume 1, Issue 4, July 2026.
ABSTRACT Background Low‐dose thiopurine therapy in combination with allopurinol (LD‐THIO/ALLO) is a widely used treatment for inflammatory bowel disease (IBD). However, little is known about the effects of in utero exposure to this combination on pregnancy and birth outcomes.
Kavitha Sivananthan, Signe Wildt, Marianne Kiszka‐Kanowitz, Gitte Pedersen, Ida Vind, Inge Nordgaard‐Lassen, Andreas Munk Petersen, Johan Burisch, Helle Kristensen, Klaus Theede   +9 more
wiley   +1 more source

Allopurinol okozta hiperszenzitivitási szindróma = Allopurinol-Induced Hypersensitivity Syndrome

Az allopurinol hatékony húgysavszintcsökkentő gyógyszer, amely az esetek többségében nem okoz mellékhatásokat, azonban a betegek 2%-ában szedése során bőrtünetek jelentkezhetnek és súlyos, allopurinol indukálta hiperszenzitivitási szindróma alakulhat ki.
Kinyó, Ágnes, Gyulai, Roland, Bata-Csörgő, Zsuzsanna, Kemény, Lajos, Lakatos, Anna, Varga, Anita, Varga, Erika   +6 more
core   +1 more source

[Cardiovascular risk in gout - Role of allopurinol?]

, 2021
The treatment of gout is subject to different national and international guidelines. These guidelines differ in the extent to which they consider cardiovascular risk factors when deciding to start allopurinol. Observational studies and limited trial data
Jong, I.C. de, Herwaarden, N. van, Pol, K.H. van der, Rongen, G.A.P.J.M.   +3 more
core  

Oxidative stress and plasma ceramides in broiler chickens

Frontiers in Physiology
The selection for rapid growth in chickens has rendered meat-type (broiler) chickens susceptible to develop metabolic syndrome and thus inflammation.
Hillar Klandorf, Vincent Dartigue
doaj   +1 more source

Structural basis of ligand selectivity in FAD/NAD(P)H‐dependent dehydrogenases: insights from trypanothione reductase and type II NADH dehydrogenase

Protein Science, Volume 35, Issue 7, July 2026.
Abstract FAD/NAD(P)H‐dependent dehydrogenases form a structurally conserved family of redox enzymes that participate in essential metabolic processes across parasites and higher organisms. Among them, trypanothione reductase (TR) is a key component of the redox metabolism of Leishmania species and represents an attractive target for antileishmanial ...
Giulia Chiara Maria Perrone, Serena Spadone, Anna Lucia Francavilla, Sara Morselli, Sabino Todisco, Margherita Ortalli, Jairo Alfonso Mendoza‐Roldan, Valeria Scaglione, Maria Noemi Sgobba, Lorenzo Guerra, Federica Belluti, Stefania Varani, Domenico Otranto, Anna De Grassi, Mariateresa Volpicella, Ciro Leonardo Pierri   +15 more
wiley   +1 more source

Transient hypofibrinogenemia due to allopurinol

, 2014
ZhiQiang Yin,1,* JiaLi Xu,2,* YongQiang Li,3,* JiPing Xia,1 Dan Luo1 1Department of Dermatology, 2Department of Oncology, 3Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, People's ...
Yin ZQ, Li YQ, Xu JL, Xia JP, Luo D
core  

Allopurinol-induced DRESS syndrome

, 2012
A 70-year-old man was admitted to our clinic with complaints of fever, jaundice, dyspnea, and generalized rash after 3 months of allopurinol treatment for gout.
Tamer, Ali, Uslan, Mustafa İhsan
core   +1 more source

Assessment on the use of allopurinol to improve safety and efficacy of mercaptopurine in pediatric patients with Acute Lymphoblastic Leukemia and Lymphoma during maintenance therapy

Cancer Reports
Background Mercaptopurine is an important component of acute lymphoblastic leukemia (ALL) and lymphoma (LLy) maintenance therapy. The 6‐thioguanine nucleosides (6‐TGN) are believed to be the primary contributor to myelosuppression and immunosuppressive ...
Tecca Barone, Smita Dandekar, Daniel McKeone, Kevin Mulieri   +3 more
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source