Results 61 to 70 of about 21,706 (181)

Temporal distribution of acute kidney injury–related hospitalizations after initiation of sodium–glucose cotransporter 2 inhibitors: A nationwide claims database analysis in older adults with an independent complementary single‐center eGFR analysis

Journal of Diabetes Investigation, EarlyView.
Among 190 older adults who experienced AKI‐related hospitalization after SGLT2 inhibitor initiation, 31.1% were hospitalized within 30 days. In an independent single‐center cohort, sustained early eGFR decline was associated with older age and use of one or two triple‐whammy‐related drug classes.
Kazuya Hiura, Ayana Tatsuno, Yamato Noto, Ryosuke Wakamatsu, Masayuki Sakunami, Ryu Kobayashi, Miki Yamashita   +6 more
wiley   +1 more source

Treatment strategies for interstitial granulomatous dermatitis: Systematic review and expert opinion

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Systematic review of 108 studies with a total of 182 patients with interstitial granulomatous dermatitis (IGD). IGD was frequently associated with systemic conditions or drug exposure. Management includes careful medication review and prompt withdrawal of potential triggers. Corticosteroids (systemic and topical) were commonly effective, while biologic
Francesco Bellinato, Sara Salvagno, Chiara Colato, Paolo Gisondi, Giampiero Girolomoni   +4 more
wiley   +1 more source

Assessment on the use of allopurinol to improve safety and efficacy of mercaptopurine in pediatric patients with Acute Lymphoblastic Leukemia and Lymphoma during maintenance therapy

Cancer Reports
Background Mercaptopurine is an important component of acute lymphoblastic leukemia (ALL) and lymphoma (LLy) maintenance therapy. The 6‐thioguanine nucleosides (6‐TGN) are believed to be the primary contributor to myelosuppression and immunosuppressive ...
Tecca Barone, Smita Dandekar, Daniel McKeone, Kevin Mulieri   +3 more
doaj   +1 more source

HLA‒B*58:01 and skin reactions in pediatric hematology and oncology patients treated with allopurinol [PDF]

Clinical and Experimental Pediatrics
Background Allopurinol is widely used to prevent hyperuricemia in patients with tumor lysis syndrome. However, its use can trigger severe cutaneous adverse reactions (SCARs) with a mortality rate of approximately 11.39%. The human leukocyte antigen (HLA)–
Parisa Maneechai, Cholada Ratanatharathron, Jassada Buaboonam, Kleebsabai Sanpakit   +3 more
doaj   +1 more source

Of mice and men—The emerging oral–gut–brain axis of health and disease

Periodontology 2000, EarlyView.
Abstract Objectives Oral health's inextricable links to systemic health are highlighted by the emerging oral–gut–brain axis and other well‐known axes. There is growing evidence of a complex oral–gut–brain axis linking mouth and gut microbiomes with the central nervous system.
Yvonne L. Hernandez‐Kapila, Daniel J. Weisenberger   +1 more
wiley   +1 more source

Drug Repurposing for Parkinson's Disease Prevention: Replication Study of Three Drugs in French Healthcare Databases

Movement Disorders, EarlyView.
Yanis Saidi, Anne Paakinaho, Eeva Pylkkö, Sirpa Hartikainen, Anna‐Maija Tolppanen, Alexis Elbaz, Ismaïl Ahmed, Anne C.M. Thiébaut, Émeline Courtois   +8 more
wiley   +1 more source

Allopurinol Use Is Associated with Decreased Incidence of Hepatic Decompensation and Overall Mortality among Individuals with Cirrhosis: A Propensity-Matched Cohort Study

GE: Portuguese Journal of Gastroenterology
Background: Cirrhosis is associated with significant morbidity and mortality. Recent studies have highlighted the potential role of allopurinol in reducing the incidence of hepatic decompensation among individuals with cirrhosis.
Mohammad Al Hayek, Bisher Sawaf, Mohammed S. Beshr, Mulham Alom, Abdelaziz H. Salam, Mouaz Haffar, Rana H. Shembesh, Ahmad Kassem, Mohammed Abu-Rumaileh, Yusuf Hallak, Shahem Abbarh, Elias Batikh, Muhammed Elhadi, Monica Tincopa   +13 more
doaj   +1 more source

Effects of Causal Beliefs About Gout on Public Views About Gout Management: A Randomized Experimental Study

Arthritis Care &Research, Volume 78, Issue 10, Page 1478-1486, October 2026.
Objective Despite well‐described biologic causes, the public views unhealthy lifestyle choices as the primary cause of gout. This study investigated how causal beliefs about gout influence the public's views about its management. Methods In a randomized study, 201 members of the public viewed one of two 2‐minute videos about gout.
Rachel Murdoch, Borislav Mihov, Anne Horne, Keith J. Petrie, Gregory D. Gamble, Lachlan Fleck, Nicola Dalbeth   +6 more
wiley   +1 more source

Randomized Controlled Trial of Herbal Extracts (Eugenia polyantha, Apium graveolens, Nigella sativa) and Allopurinol Effect on Serum Uric Acid, Urinary Uric Acid and High Sensitivity C-Reactive Protein Levels in Subject with Hyperuricemia

Indonesian Journal of Rheumatology, 2019
Background: Eugenia polyantha, Apium graveolens, and Nigella sativa are extracts which in preclinical trial can reduce uric acid serum, increase urinary uric acid excretion. Allopurinol is an inhibitor of the xanthine oxidase enzyme which can also reduce
Bantar Sutoko, Rakhma Yanti Hellmi, Ika Vemillia W, Stepanus Agung L   +3 more
doaj   +1 more source

Diagnostic Delay in Pediatric Nasopharyngeal Burkitt Lymphoma Presenting With Chronic Otalgia and Multiple Cranial Nerve Palsies: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Persistent unilateral otalgia, especially when refractory to treatment and associated with cranial nerve signs, should prompt early imaging and nasopharyngeal evaluation to avoid delayed diagnosis of aggressive malignancies such as Burkitt lymphoma.
Sultaneh Haddad, Abdulwahhab Al‐Shaikhli, Fehmat Hallak, Halima Hamdan, Ahmed Farag, Ranim Nakhal, Sameh Alramdani, Mohammad Obada Alsadi, Rawad Hamza, Othman Hamdan   +9 more
wiley   +1 more source