Results 81 to 90 of about 47,188 (263)

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen   +3 more
wiley   +1 more source

Effectiveness of Allopurinol and Quercetin inclusion in a complex treatment of stable angina pectoris – peculiarities of biomarkers and homeostatic indices changes

open access: yesZaporožskij Medicinskij Žurnal, 2017
Objective – to study the effectiveness of Allopurinol and Quercetin inclusion in a complex treatment of stable angina pectoris and peculiarities of biomarkers and homeostatic indices changes. Materials and Methods.
V.K. Tashchuk   +2 more
doaj   +1 more source

Agrimoniin Alleviates Ferroptosis in Cold‐Stored DCD Liver Grafts Through Activation of the Nrf‐2 Pathway

open access: yesCell Proliferation, EarlyView.
Supplementing the liver preservation solution with agrimoniin protects donation after cardiac death (DCD) grafts by activating the Nrf‐2 pathway. This reduces ferroptosis, oxidative stress, and inflammation during cold storage, significantly improving graft viability.
Enqiang Chang   +5 more
wiley   +1 more source

MR-GNN: Multi-Resolution and Dual Graph Neural Network for Predicting Structured Entity Interactions

open access: yes, 2019
Predicting interactions between structured entities lies at the core of numerous tasks such as drug regimen and new material design. In recent years, graph neural networks have become attractive.
Chen, Long   +4 more
core   +1 more source

Effect of allopurinol on all-cause mortality in adults with incident gout: propensity score–matched landmark analysis [PDF]

open access: yes, 2015
Objective: To examine the association between allopurinol use and all-cause mortality for patients with incident gout. Methods: We compared all-cause mortality in incident gout patients who received allopurinol for at least 6 months within the ...
Doherty, Michael   +4 more
core   +1 more source

Fatigue and mood disorders are highly prevalent in patients with inflammatory bowel disease: A single‐centre, cross‐sectional study using patient‐reported outcomes

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Fatigue is a common and debilitating symptom in inflammatory bowel disease (IBD), yet it remains under‐recognised in clinical practice. This study aimed to quantify fatigue among Australian patients with IBD and examine associations with disease control, psychological distress and quality of life (QoL).
Andrew Chen, Darren Wong
wiley   +1 more source

A randomized controlled study of allopurinol mouthwash in the prevention of 5-fluorouracil-induced oral mucositis

open access: yesJournal of Health Science and Medical Research (JHSMR), 2009
Objectives: To formulate an allopurinol suspension; study the chemical and physical stability of the formulation and compare the efficacy and adverse drug reactions of a 5 mg/mL allopurinol mouthwash with a placebo in the prevention of 5-fluorouracil (5 ...
P Kaewmanee   +4 more
doaj  

Assessment on the use of allopurinol to improve safety and efficacy of mercaptopurine in pediatric patients with Acute Lymphoblastic Leukemia and Lymphoma during maintenance therapy

open access: yesCancer Reports
Background Mercaptopurine is an important component of acute lymphoblastic leukemia (ALL) and lymphoma (LLy) maintenance therapy. The 6‐thioguanine nucleosides (6‐TGN) are believed to be the primary contributor to myelosuppression and immunosuppressive ...
Tecca Barone   +3 more
doaj   +1 more source

2448 The effect of allopurinol on pediatric patients undergoing maintenance chemotherapy for acute lymphoblastic leukemia or lymphoblastic lymphoma

open access: yesJournal of Clinical and Translational Science, 2018
OBJECTIVES/SPECIFIC AIMS: This study aims to assess the safety, feasibility, clinical benefits and pharmacodynamics of adding allopurinol to standard maintenance therapy that includes 6-mecaptopurine (6-MP) in pediatric patients with acute lymphoblastic ...
Mariam M. Bhuiyan   +2 more
doaj   +1 more source

Interventions for treating oral mucositis for patients with cancer receiving treatment [PDF]

open access: yes, 2010
Background Treatment of cancer is increasingly effective but is associated with short and long term side effects. Oral and gastrointestinal side effects, including oral candidiasis, remain a major source of illness despite the use of a variety of agents ...
Clarkson, Jan E.   +5 more
core   +8 more sources

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