Results 161 to 170 of about 2,738 (186)
High HLA Sensitization After Early Renal Allograft Vascular Thrombosis. [PDF]
Transpl IntPérez-Sáez MJ +10 more
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Innate allorecognition in transplantation
The Journal of Heart and Lung Transplantation, 2021Successful allogeneic transplantation has been made possible by suppressing activation of the adaptive immune system. Current immunosuppressive therapy prevents rejection by targeting T and B cells. Despite this effective treatment, it is the innate immune system, which includes dendritic cells, monocytes, natural killer cells, that is responsible for ...
Khodor I, Abou-Daya +1 more
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The Hydractinia allorecognition system
Immunogenetics, 2021Hydractinia symbiolongicarpus is a colonial hydroid and a long-standing model system for the study of invertebrate allorecognition. The Hydractinia allorecognition system allows colonies to discriminate between their own tissues and those of unrelated conspecifics that co-occur with them on the same substrate.
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The Molecular Basis of Allorecognition
Annual Review of Immunology, 1993Until recently it was generally assumed that the focus of T cell receptor recognition of allogeneic MHC molecules was the polymorphic regions on the molecule that differed between responder and stimulator. It is now clear that all T cell recognition, including self-tolerance and allorecognition, involves both the MHC molecule and its associated peptide
L A, Sherman, S, Chattopadhyay
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Tolerogenic response: Allorecognition pathways
Transplant Immunology, 2006The induction of immune tolerance in transplant recipients has been sought for many years but only a fundamental understanding of the immunological mechanisms underlying graft rejection will allow manipulation of the anti-graft immune response. In general, acute rejection is better understood and treated than chronic rejection, as they occur through ...
A, Caballero +5 more
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Current Opinion in Nephrology and Hypertension, 1993
Understanding the nature of allorecognition is fundamental to the design of antigen-specific therapies for transplantation. As recently as 10 years ago it was generally believed that recognition of major histocompatibility complex (MHC) molecules by T lymphocytes was direct and represented the "simplest" kind of T-lymphocyte interaction.
A M, Krensky, C, Clayberger
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Understanding the nature of allorecognition is fundamental to the design of antigen-specific therapies for transplantation. As recently as 10 years ago it was generally believed that recognition of major histocompatibility complex (MHC) molecules by T lymphocytes was direct and represented the "simplest" kind of T-lymphocyte interaction.
A M, Krensky, C, Clayberger
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Structural aspects of allorecognition
Current Opinion in Immunology, 1991The phenomenon of T-cell allorecognition of foreign major histocompatibility molecules has been one of the more enigmatic aspects of T-cell immunology. The molecular basis for allorecognition is unfolding as a result of the application of major histocompatibility complex structure/function analyses in the light of current insights into the three ...
R, Lechler, G, Lombardi
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Allorecognition in biological systems
Developmental & Comparative Immunology, 1981Abstract Colonial marine organisms of several phyla show the capacity for allogeneic recognition and response. In the colonial tunicate Botryllus , colony fusibility characteristics are determined by a single Mendelian locus with multiple co-dominant alleles.
Virginia L. Scofield, Irving L. Weissman
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Indirect Allorecognition: Not Simple but Effective
Transplantation, 2008Donor dendritic cells are potent but short-lived stimulators of early transplant rejection, and recipient antigen presenting cells presenting donor major histocompatibility complex peptides sustain immunoreactivity and contribute to chronic rejection.
Eleanor M, Bolton +2 more
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