Results 81 to 90 of about 1,267 (159)

Implications of Fragment-Based Drug Discovery in Tuberculosis and HIV. [PDF]

Pharmaceuticals (Basel), 2022
Mallakuntla MK, Togre NS, Santos DB, Tiwari S.   +3 more
europepmc   +1 more source

Nature-Inspired Pathogen and Cancer Protein Covalent Inhibitors: From Plants and Other Natural Sources to Drug Development. [PDF]

Pathogens
Roviello GN.
europepmc   +1 more source

Dual Inhibitory Potential of Conessine Against HIV and SARS-CoV-2: Structure-Guided Molecular Docking Analysis of Critical Viral Targets. [PDF]

Viruses
Abdulkareem AH, Alani MT, Awad SA, Al-Meani SAL, Ahmed MM, Abdulkareem EH, Khaleel ZM.   +6 more
europepmc   +1 more source

In-silico identification of phytochemical compounds from various medicinal plants as potent HIV-1 non-nucleoside reverse transcriptase inhibitors utilizing molecular docking and molecular dynamics simulations. [PDF]

Biol Methods Protoc
Danladi S, Adeniyi AA, Sani ZI, Temitope A.   +3 more
europepmc   +1 more source

Targeting Ribonucleases with Small Molecules and Bifunctional Molecules. [PDF]

ACS Chem Biol, 2023
Borgelt L, Wu P.
europepmc   +1 more source

Pharmacophore modeling: advances and pitfalls. [PDF]

Front Mol Biosci
Elsaka MY, Taha MM, Tayel A, Tawfik HO, Ibrahim MAA, Shoeib T.   +5 more
europepmc   +1 more source

Structures reveal how the Cas1-2/3 integrase captures, delivers, and integrates foreign DNA into CRISPR loci. [PDF]

Structure
Henriques WS, Bowman J, Hall LN, Gauvin CC, Wei H, Kuang H, Zimanyi CM, Eng ET, Santiago-Frangos A, Wiedenheft B.   +9 more
europepmc   +1 more source

Advances in pharmacological interventions for hepatic fibrosis: from pathogenic mechanisms to novel therapeutic targets. [PDF]

Ann Med
Zhang W, Shao T, Wang C, Wang S, An L.
europepmc   +1 more source

Oligomeric HIV-1 integrase structures reveal functional plasticity for intasome assembly and RNA binding. [PDF]

Nat Commun
Jing T, Shan Z, Dinh T, Biswas A, Jang S, Greenwood J, Li M, Zhang Z, Gray G, Shin HJ, Zhou B, Passos D, Strutzenberg TS, Aiyer S, Andrade L, Zhang Y, Li Z, Craigie R, Engelman AN, Kvaratskhelia M, Lyumkis D.   +20 more
europepmc   +1 more source

Mechanism of action of allosteric HIV-1 integrase inhibitors

, 2015
Alison Slaughter
openalex   +1 more source