Results 111 to 120 of about 63,430 (242)

Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: Implications for allosteric regulation

, 2000
James A. Endrizzi, Peter T. Beernink, Tom Alber, H. K. Schachman   +3 more
openalex   +1 more source

DPPH‐based Antioxidant Screening and Cellulase‐assisted Hydrodistillation of Matourea azurea: Improved Essential Oil Yield and Density Functional Theory Insights Into a Rare Terpene

Chemistry &Biodiversity, EarlyView.
ABSTRACT Essential oils are rich in bioactive molecules like terpenes and phenolic compounds, but have low yields, making process efficiency crucial. Enzyme‐assisted hydrodistillation is a sustainable alternative, enhancing oil release by degrading the cell wall.
Júlio César Gonçalves de Souza, Leiliane do Socorro Sodré de Souza, Ari de Freitas Hidalgo, Guilherme Teixeira de Azevedo, Giovana Lima de Souza, Caroline Dutra Lacerda, Sergio Duvoisin Junior, Anderson Mathias Pereira   +7 more
wiley   +1 more source

Allosteric regulation of L-lactate dehydrogenase: Beyond effector-mediated tetramerization. [PDF]

Protein Sci
Cai H, Shulami S, Štefanić Z, Hrenar T, Maršavelski A, Fishman A.   +5 more
europepmc   +1 more source

Unveiling the molecular basis of lobeline's allosteric regulation of NMDAR: insights from molecular modeling. [PDF]

Sci Rep, 2023
Remya C, Variyar EJ, Omkumar RV, Sadasivan C, Dileep KV.   +4 more
europepmc   +1 more source

ADPglucose pyrophosphorylase’s N-terminus: Structural role in allosteric regulation [PDF]

, 2006
Clarisa Maria Bejar, Miguel A. Ballícora, Alberto Á. Iglesias, J. Preiss   +3 more
openalex   +1 more source

Hazelnut: Explorations toward the Biocatalytic Synthesis of its Aroma Precursor

ChemBioChem, EarlyView.
This article proposes a biosynthetic route for synthesizing filbertone, the principal flavor compound of hazelnut, through a multienzyme cascade. The pathway uses D‐amino acid oxidase, threonine deaminase, and a regioselective transketolase from Geobacillus stearothermophilus to produce a sustainable, natural hazelnut aroma precursor, addressing ...
Mireia Salvadó‐Pau, Wolf‐Dieter Fessner, Zvjezdana Findrik Blažević, Michael Breuer   +3 more
wiley   +1 more source

Dynamic and structural insights into allosteric regulation on MKP5 a dual-specificity phosphatase. [PDF]

Nat Commun
Skeens E, Maschietto F, Manjula R, Shillingford S, Murphy J, Lolis EJ, Batista VS, Bennett AM, Lisi GP.   +8 more
europepmc   +1 more source

Allosteric Regulation of Glycogen Phosphorylase by Order/Disorder Transition of the 250' and 280s Loops. [PDF]

Biochemistry, 2023
Kish M, Subramanian S, Smith V, Lethbridge N, Cole L, Vollmer F, Bond NJ, Phillips JJ.   +7 more
europepmc   +1 more source

Proteolytic Fragments of Insulysin (IDE) Retain Substrate Binding but Lose Allosteric Regulation [PDF]

, 2006
Eun Suk Song, Clint Cady, Michael G. Fried, Louis B. Hersh   +3 more
openalex   +1 more source

Activity‐Enhancing Mutations in an LmrR‐Based Artificial Metalloenzyme Destabilize the Protein Scaffold and Alter its Conformational Plasticity

ChemBioChem, EarlyView.
The protein LmrR is a versatile scaffold to design artificial metalloenzymes. Here, we show that the M8D/A92E (DE) mutations that result in a much more efficient catalyst, destabilize the protein dimerization interface and alter the conformation landscape when binding metal cofactor and substrates are shown.
Adil A. Safeer, Fabrizio Casilli, Wouter Beugelink, Gerard Roelfes, Marc Baldus, Hugo van Ingen   +5 more
wiley   +1 more source