Results 111 to 120 of about 19,917 (239)
Mechanisms of catalysis and allosteric regulation of yeast chorismate mutase from crystal structures [PDF]
, 1997 Norbert Sträter +3 more
openalex +1 more source
Synthesis of β,β‐Dinaphthyl Amino Acids: Towards Molecular Gearing in Peptides and Mini‐Proteins
Chemistry – A European Journal, EarlyView.Amino acids bearing two aromatic side chains are studied here for their ability to align in rotor‐like assemblies in a synthetic protein. Based on quantitative analysis of 1H NMR reference nuclei, we investigate a correlated molecular rotor‐type behavior whose dynamic nature stands in remarkable contrast to established systems in the field of molecular
Timo Zimmer +2 more
wiley +1 more source
iScience, 2020 Summary: Insulin regulates glucose metabolism through thousands of regulatory mechanisms; however, which regulatory mechanisms are keys to control glucose metabolism remains unknown.
Satoshi Ohno +10 more
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The Water Effect on Allosteric Regulation of Hemoglobin Probed in Water/Glucose and Water/Glycine Solutions [PDF]
, 1996 M. F. Colombo +1 more
openalex +1 more source
Chemistry – A European Journal, EarlyView.We offer a new labeling approach to introduce isolated 15N−13C−1H spin systems to the side chains of arginine residues. The labeling scheme delivers high‐resolution NMR spectra to study large protein complexes. The interaction between ubiquitin and the third Src homology 3 domain of yeast protein Sla1 (Sla1 SH3‐3) has been analyzed, highlighting the ...
Darja I. Rohden +3 more
wiley +1 more source
A new approach for extracting information from protein dynamics
Proteins: Structure, Function, and Bioinformatics, Volume 91, Issue 2, Page 183-195, February 2023., 2023 Abstract Increased ability to predict protein structures is moving research focus towards understanding protein dynamics. A promising approach is to represent protein dynamics through networks and take advantage of well‐developed methods from network science.
Jenny Liu +2 more
wiley +1 more source
Allosteric Differentiation of Al(I) Reactivity
Chemistry – A European Journal, Accepted Article.The dimeric potassium alumanyl, [{SiNDipp}AlK]2 ({SiNDipp} = {CH2SiMe2N(Dipp)}2; Dipp = 2,6‐i‐Pr2C6H3), reacts with two equivalents of PhCºCR (R = Ph or SiMe3) and the exclusive formation of the aluminacyclopropene derivatives, [{SiNDipp}Al{h2‐C2(R1)(R2)}].
Michael Stephen Hill +6 more
wiley +1 more source
Proteins: Structure, Function, and Bioinformatics, Volume 91, Issue 2, Page 237-255, February 2023., 2023 Abstract The heat shock protein 70 kDa (Hsp70) chaperone system serves as a critical component of protein quality control across a wide range of prokaryotic and eukaryotic organisms. Divergent evolution and specialization to particular organelles have produced numerous Hsp70 variants which share similarities in structure and general function, but ...
Markus Schneider, Iris Antes
wiley +1 more source
Allosteric Regulation of Artificial Phosphoesterase Activity by Metal Ions [PDF]
, 2000 Igor O. Fritsky +2 more
openalex +1 more source
Functional, pathogenic, and pharmacological roles of protein folding intermediates
Proteins: Structure, Function, and Bioinformatics, EarlyView., 2023 Abstract Protein expression and function in eukaryotic cells are tightly harmonized processes modulated by the combination of different layers of regulation, including transcription, processing, stability, and translation of messenger RNA, as well as assembly, maturation, sorting, recycling, and degradation of polypeptides.
Emiliano Biasini, Pietro Faccioli
wiley +1 more source