Results 151 to 160 of about 67,162 (289)

Structural mechanisms of allosteric regulation in the human cis-prenyltransferase complex. [PDF]

Nat Commun
Giladi M, Kredi S, Guardiani C, Aviram L, Vaňková P, Gaizinger Y, Man P, Giacomello A, Haitin Y.   +8 more
europepmc   +1 more source

Allosteric regulation of glycerol kinase by enzyme IIIglc of the phosphotransferase system in Escherichia coli and Salmonella typhimurium [PDF]

, 1985
Maria Novotny, Willard L. Frederickson, E. Bruce Waygood, Milton H. Saier   +3 more
openalex   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

A dynamic structural framework for the allosteric regulation of Hsp70 chaperones. [PDF]

J Biol Chem
Rohland L, Kityk R, Smalinskaitė-Wolf L, Lashkul V, Mayer MP.   +4 more
europepmc   +1 more source

Enzyme Regulation: Allosteric Cosmos [PDF]

Nature, 1970
openaire   +1 more source

Allosteric regulation of L-lactate dehydrogenase: Beyond effector-mediated tetramerization. [PDF]

Protein Sci
Cai H, Shulami S, Štefanić Z, Hrenar T, Maršavelski A, Fishman A.   +5 more
europepmc   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source

Dynamic and structural insights into allosteric regulation on MKP5 a dual-specificity phosphatase. [PDF]

Nat Commun
Skeens E, Maschietto F, Manjula R, Shillingford S, Murphy J, Lolis EJ, Batista VS, Bennett AM, Lisi GP.   +8 more
europepmc   +1 more source

Construction of Enzymes with Synthetic Allosteric Regulation to Control Metabolic Pathways of Escherichia coli

, 2019
Dominik Beuter
openalex   +1 more source

Artificial intelligence strategies for predicting kinase inhibitor resistance: A comprehensive review of methods, challenges, and future perspectives

Journal of Intelligent Medicine, EarlyView.
Abstract Kinase inhibitors are essential in targeted cancer therapy, yet resistance often emerges through secondary mutations, activation of compensatory signaling pathways, or drug‐efflux mechanisms. Artificial intelligence (AI) provides a workflow‐based strategy rather than a list of unrelated tools for predicting and addressing kinase‐inhibitor ...
Faris Hassan, Mohanad Ali Deifallah, Alaa Zaghloul, Rania Elgohary   +3 more
wiley   +1 more source