Results 151 to 160 of about 127,473 (347)

Advances in analyzing and engineering plant metabolic diversity

Applications in Plant Sciences, EarlyView.
Kira J. Tiedge, Federico Roda, Stacey D. Smith, Gaurav D. Moghe   +3 more
wiley   +1 more source

Internal Ubiquitin Electrophiles for Covalent Trapping and Inhibition of Deubiquitinases

ChemBioChem, Accepted Article.
The ubiquitin (Ub) system governs vital cellular processes in eukaryotic biology through an intricate network of Ub‐protein interactions. While semisynthetic C‐terminal Ub electrophiles (UbEs) are widely used to study Ub transfer and deubiquitinase (Dub) activity, they are limited to probing the active site while leaving other functionally important ...
Chittaranjan Das, Nipuni M. Pannala, Rishi S. Patel, Abhijith Saseendran Anit, Debapriya Bhattacharya, Kristos Negron Teron, Bryon Drown, Rudi Fasan   +7 more
wiley   +1 more source

Allosteric Regulation of Artificial Phosphoesterase Activity by Metal Ions [PDF]

, 2000
Igor O. Fritsky, Reina Ott, Roland Krämer   +2 more
openalex   +1 more source

The NLS3 Motif in TPX2 Regulates Spindle Architecture in Xenopus Egg Extracts

Cytoskeleton, EarlyView.
ABSTRACT A bipolar spindle composed of microtubules and many associated proteins functions to segregate chromosomes during cell division in all eukaryotes, yet both spindle size and architecture vary dramatically across different species and cell types.
Guadalupe E. Pena, Xiao Zhou, Lauren Slevin, Christopher Brownlee, Rebecca Heald   +4 more
wiley   +1 more source

Multiple allostery in the regulation of PDGFR beta kinase activities

Acta Biochimica et Biophysica Sinica
Platelet-derived growth factor receptor beta (PDGFRβ), a type III receptor tyrosine kinase (RTK) with a featured kinase insert, regulates important cellular functions. Dysregulation of PDGFRβ is associated with cardiovascular and fibrosis diseases. Thus,
Zhang Yanfeng, Wang Meimei, Shao Guangcan, Shang Qingbin, Dong Mengqiu, Qin Xiaohong, Mi Li-Zhi   +6 more
doaj   +1 more source

Biophysical Mechanism of Allosteric Regulation of Actin Capping Protein. [PDF]

J Mol Biol, 2023
Mooren OL, Stuchell-Brereton MD, McConnell P, Yan C, Wilkerson EM, Goldfarb D, Cooper JA, Sept D, Soranno A.   +8 more
europepmc   +1 more source

Eigenvector Centrality Distribution for Characterization of Protein Allosteric Pathways

, 2018
Determining the principal energy pathways for allosteric communication in biomolecules, that occur as a result of thermal motion, remains challenging due to the intrinsic complexity of the systems involved.
Batista, Victor S., Hendrickson, Heidi, Ho, Junming, Lisi, George P., Loria, J. Patrick, Morzan, Uriel N., Negre, Christian F. A., Pal, Rhitankar, Rivalta, Ivan   +8 more
core  

Biochemical mechanism of uracil uptake regulation in Escherichia coli B. Allosteric effects on uracil phosphoribosyltransferase under stringent conditions.

, 1977
R Fast, Ola Sköld
openalex   +1 more source

Dissecting the Structural Organization, Recruitment and Activation Mechanisms of Centrosomal γ‐TuRCs

Cytoskeleton, EarlyView.
ABSTRACT Visualizing human centrosomes using cryo‐electron tomography revealed the native structure and molecular organization of γ‐tubulin ring complexes (γ‐TuRCs). γ‐TuRCs localized to two distinct centrosomal pools, one in the pericentriolar material (PCM) and another in the centriole lumen, which is released during mitosis.
Florian W. Hofer, Martin Würtz, Qi Gao, Bram J. A. Vermeulen, Elmar Schiebel, Stefan Pfeffer   +5 more
wiley   +1 more source

Monovalent Cation Effects on Lysine-sensitive Aspartokinase Catalytic Activity and Allosteric Regulation

, 1974
Jane D. Funkhouser, W. Smith
openalex   +1 more source