Results 261 to 270 of about 127,473 (347)

Ligand Recognition and Function of TAARs

Sensory Neuroscience, EarlyView.
The trace amine‐associated receptor (TAAR) family represents a highly conserved group of G protein‐coupled receptors (GPCRs) in vertebrates. TAARs specifically bind to different amine ligands and mediate a variety of physiological and behavioral processes.
Kang‐Ying Qian, Yue Hao, Zheng Wang, Qian Li   +3 more
wiley   +1 more source

Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens. [PDF]

Elife
Ober VT, Githure GB, Volpato Santos Y, Becker S, Moya Munoz G, Basquin J, Schwede F, Lorentzen E, Boshart M.   +8 more
europepmc   +1 more source

Crystal structure and biochemical properties of putrescine carbamoyltransferase from Enterococcus faecalis: Assembly, active site, and allosteric regulation [PDF]

, 2012
Dashuang Shi, Xiaolin Yu, Gengxiang Zhao, Jeremy Ho, Shennon Lu, Norma M. Allewell, Mendel Tuchman   +6 more
openalex   +1 more source

Tailored Metal‐Organic Framework‐Based Enzyme Hybrids: Immobilization Strategies, Improved Performance, and Biological Applications

Small Science, EarlyView.
Metal‐organic frameworks (MOFs) offer versatile platforms for enzyme immobilization to overcome their inherent fragility. However, challenges such as restricted conformation and mass transfer limitations remain. Advances in precise MOF design can help overcome these obstacles, expanding their applicability across diverse fields, highlighting the ...
Xiang Xu, Jiacheng Wan, Jun Sun, Lina Wu, Jianping Lei   +4 more
wiley   +1 more source

A novel type of allosteric regulation: Functional cooperativity in monomeric proteins [PDF]

, 2012
Ilia G. Denisov, Stephen G. Sligar
openalex   +1 more source

A Chemogenetic Toolkit for Inducible, Cell Type‐Specific Actin Disassembly

Small Methods, EarlyView.
ChiActs are novel actin‐perturbing genetic tools that can be rapidly activated by chemical actuators and optogenetically targeted to distinct subcellular locations using light. ChiActs rapidly induce actin disassembly in several model cell types and are able to perturb actin‐dependent nano‐assembly and cellular functions, including inhibition of ...
Tien‐Hung Lan, Nicholas Ambiel, Yi‐Tsang Lee, Tatsuki Nonomura, Yubin Zhou, J. Bradley Zuchero   +5 more
wiley   +1 more source

Allosteric regulation of Keap1 by 8β-hydroxy-α-cyclocostunolide for the treatment of acute lung injury. [PDF]

Acta Pharm Sin B
Zhang J, Zhang M, Zhu QM, Xu XR, Feng YL, Lin S, Qiu F, Sun CP.   +7 more
europepmc   +1 more source

Novel mutator mutants of E. coli nrdAB ribonucleotide reductase: Insight into allosteric regulation and control of mutation rates [PDF]

, 2012
Deepti Ahluwalia, Rachelle J. Bienstock, Roel M. Schaaper   +2 more
openalex   +1 more source

Design, Mechanisms, and Applications of DNA‐Mediated Dynamically Reconfigurable Plasmonic Gold Nanostructures

Small Methods, EarlyView.
This review provides key principles of designing and synthesizing reconfigurable plasmonic gold nanostructures for generating and controlling physical, chemical, and biological properties and functions. The recent advances in the biological and materials applications of dynamically reconfigurable plasmonic gold nanostructures are also summarized ...
So Young Choi, Jieun Kim, Eun Ho Song, Eunhye Park, Jingrui Wu, Juyeon Yoo, Jwa‐Min Nam   +6 more
wiley   +1 more source

Nanozymes in Reactive Oxygen Species‐Dependent Diseases: From Design and Preclinical Studies to Clinical Translation Prospects

Small Structures, EarlyView.
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou, Jingyu Yan, Chenying Cui, Yurong Xu, Kaifang Zhang, Meijun Du, Zhuowei Zhang, Xiuping Wu, Bing Li   +8 more
wiley   +1 more source