Results 261 to 270 of about 130,849 (328)

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

Structural basis of the allosteric regulation of cyanobacterial glucose-6-phosphate dehydrogenase by the redox sensor OpcA. [PDF]

Proc Natl Acad Sci U S A
Doello S, Shvarev D, Theune M, Sauerwein J, Klon A, Keskin E, Boehm M, Gutekunst K, Forchhammer K.   +8 more
europepmc   +1 more source

Regulation of vitamin B12-dependent ribonucletide reductase from Rhizobium meliloti by allosteric effectors.

, 1980
Shinji Inukai, Kazuyoshi Sato, Shoichi Shimizu   +2 more
openalex   +2 more sources

The Oxytocin Receptor in Spermatozoa May Originate From Both Spermatogenesis and Epididymal Maturation, and Regulates Capacitation

Andrology, EarlyView.
Abstract Background The oxytocin receptor (OR) is a G‐protein‐coupled receptor recently identified in human spermatozoa, whose origin and role in sperm physiology remain unknown. Objectives In this study, using the pig as a model, we examine the presence of the OR in ejaculated spermatozoa through immunofluorescence and immunoblotting, and investigate ...
Jesús Martínez‐Hernández, Ferran Garriga, Adeel Ahmad, Lorena Padilla, Carolina Maside, Sergi Bonet, Isabel Barranco, Jordi Roca, Luis Miguel Pastor, Marc Yeste   +9 more
wiley   +1 more source

Cooperative Substructure and Energetics of Allosteric Regulation of the Catalytic Core of the E3 Ubiquitin Ligase Parkin by Phosphorylated Ubiquitin. [PDF]

Biomolecules
Ye X, Kotaru S, Lopes R, Cravens S, Lasagna M, Wand AJ.   +5 more
europepmc   +1 more source

Reviewer #2 (Public Review): Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens

openalex   +1 more source

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

British Journal of Pharmacology, EarlyView.
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley   +1 more source

The mechanism of allosteric regulation of calcium-independent phospholipase A₂ by ATP and calmodulin binding to the ankyrin domain. [PDF]

Proc Natl Acad Sci U S A
Mouchlis VD, Hsu YH, Hayashi D, Cao J, Li S, McCammon JA, Dennis EA.   +6 more
europepmc   +1 more source

Psilocybin as a novel treatment for chronic pain

British Journal of Pharmacology, EarlyView.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey, Reena Lasrado, Maria Maiarú, Gary J. Stephens   +3 more
wiley   +1 more source

Mecanismo estrutural de regulação alostérica por potássio da enzima adenosina quinase : Structural mechanism of allosteric regulation by potassium of the enzyme adenosine kinase

, 2019
Renata Rocha de Oliveira
openalex   +1 more source