Results 41 to 50 of about 121,830 (268)

Insight in the properties of WO3|Y: A first-principle study

Results in Physics, 2019
In this paper, the properties of WO3|Y when yttrium atoms are adsorbed on the surface of WO3 are studied systematically using first-principles calculations.
Xieyi Zhang, Xianwei Ren, Zhengbing Xiao, Yuanchun Huang   +3 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

The effect of room temperature pre-ageing on tensile and electrical properties of thermomechanically treated Al-Mg-Si alloy [PDF]

Journal of Mining and Metallurgy. Section B: Metallurgy, 2002
A commercial Al - 0.62%Mg - 0.57%Si was thermomechanically treated (TMT). The TMT process included solution treatment, room temperature preageing, drawing (e=95%) and final ageing.
Martinova Z., Damgaliev D., Hirsh M.
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Effect of Heating Rate on Creep Aging Behavior of 2219 Aluminum Alloy

Cailiao gongcheng, 2018
Effect of heating rate on creep aging behavior and mechanical properties in the process of creep aging forming of 2219 aluminum alloy was studied. In order to simulate the temperature conditions of the component in autoclave, heating rate was reduced to ...
LIU Ling-feng, ZHAN Li-hua, LI Wen-ke
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Modeling and Simulation of the Static Recrystallization of 5754 Aluminium Alloy by Cellular Automaton

Metals, 2018
To study the factors that affect the mechanical properties of materials, double-pass hot compression tests were performed under different deformation parameters using a Gleeble-3500 thermo-simulation machine.
Changqing Huang, Xiaodong Jia, Zhiwu Zhang   +2 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Development and application analysis of ceramic composites armor for helicopter

Journal of Aeronautical Materials, 2019
At present，lightweight armour has been fitted in foreign military helicopters for gunships and transport. By contrast，the armor configuration of domestic helicopters is still a big gap compared with Europe and America in the level type，quantity and ...
WU Yue, WANG Xudong, LIU Di, LI Jiongli, GUO Jianqiang, LI Wenbo, ZHANG Haiping, CAO Zhen   +7 more
doaj   +1 more source