Results 41 to 50 of about 1,494,058 (361)

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Possible Effects and Mechanisms of Ultrasonic Cavitation on Oxide Inclusions during Direct-Chill Casting of an Al Alloy

open access: yesMetals, 2018
Oxide films or inclusions can reduce the continuity and integrity of materials and they always lead to a significant reduction in the mechanical properties of an aluminum alloy.
Yun Zhang   +6 more
doaj   +1 more source

XX. On the alloys of steel [PDF]

open access: yesPhilosophical Transactions of the Royal Society of London
The alloys of steel made on a small scale in the laboratory of the Royal Institution proving to be good, and the experiments having excited a very considerable degree of interest both at home and abroad, gave encouragement to attempt the work on a more extended scale, and we have now the pleasure of stating, that alloys similar to those made in the ...
Stodart, J., Faraday, M.
openaire   +4 more sources

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Microstructure and Mechanical Properties of Friction Stir Welded Joint of an Aluminum Alloy Sheet 6005A-T4

open access: yesMetals, 2019
The 6005A-T6 alloy had been widely applied in rail transmit industry due to its combination properties of moderate strength, superior resistance to corrosion, and excellent extrusion plasticity.
Xiaofei Sheng   +6 more
doaj   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Alloys [PDF]

open access: yesScientific American, 1894
n ...
openaire   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Study of Adsorption of Hydrogen on Al, Cu, Mg, Ti Surfaces in Al Alloy Melt via First Principles Calculation

open access: yesMetals, 2017
Adsorption of hydrogen on Al(111), Cu(111), Mg(0001), and Ti(0001) surfaces have been investigated by means of first principles calculation. The calculation of surface energy indicates that Mg(0001) is the most stable surface, while Ti(0001) is the most ...
Yu Liu   +3 more
doaj   +1 more source

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