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Rhein and Aloe-Emodin Kinetics from Senna Laxatives in Man
Pharmacology, 2008Therapeutic doses of two laxatives (Agiolax® and Sennatin®) were repeatedly administered to 10 healthy volunteers in a two-way change-over design. Blood samples were collected up to 96 h after the first dose, and plasma levels of total aloe-emodin and rhein were determined simultaneously with a sensitive (lower limit of quantification: 0.5 ng aloe ...
G, Krumbiegel, H U, Schulz
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Chemical Reactivity of Aloe-Emodin and Its Hydroxylation Metabolites to Thiols
Chemical Research in Toxicology, 2019Aloe-emodin (AE), an anthraquinone derivative, is a bioactive ingredient isolated from rhubarb which is used to treat inflammatory illnesses in China and many other countries in Asia. AE has shown a wide range of pharmacological effects. Recent studies showed that exposure to AE could cause DNA damage and cytotoxicity.
Xu Wang +8 more
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Aloe emodin decreases the ERK-dependent anticancer activity of cisplatin
Cellular and Molecular Life Sciences, 2005The present study describes the ability of an anthraquinone derivative aloe emodin (AE) to reduce the cytotoxic activity of the platinum(II)-based anticancer agent cisplatin toward murine L929 fibrosarcoma and C6 glioma cell lines. The protective effect of AE was demonstrated by MTT and crystal violet assays for cell viability, and involved supression ...
Mijatović, Sanja +6 more
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Einfache Synthese des (?+)-6-Desoxycarminomycinons aus Aloe-Emodin
Angewandte Chemie International Edition in English, 1983AbstractDas vollständige Manuskript dieser Zuschrift erscheint in: Angew. Chem. Suppl. 1983, 1267.
Karsten Krohn, Burkhard Sarstedt
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Estimation of Aloe-Emodin and Aloins in Curacao Aloes
Analytical Chemistry, 1947K. G. Stone, N. H. Furman
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Antibacterial activity of aloe emodin and aloin A isolated from Aloe excelsa
2009Different extracts of leaves of Aloe excelsa were prepared and two compounds; 1,8-dihydroxy-3-hydromethyl-9,10-antracenedione and 10-C-b-D-glucopyranosyl-1,8-dihydroxymethyl-9-anthracenone, were isolated and tested for antibacterial activities against four Gram negative and five Gram positive bacterial strains.
Coopoosamy, RM, Magwa, ML
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Methylation and hydroxylation studies on aloe-emodin
The Journal of Organic Chemistry, 1980Jose Alexander +4 more
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Aloe-emodin: A review of its pharmacology, toxicity, and pharmacokinetics
Phytotherapy Research, 2020Jing Fu, Longtai You, Xiaoxv Dong
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