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Use of amifostine, a novel cytoprotective, in alpha-amanitin poisoning.
Clinical toxicology (Philadelphia, Pa.), 2005Mortality from ingestions of the mushroom Amanita phalloides remains as high as 20-40% with many surviving patients requiring liver transplantation. A variety of treatments for Amanita ingestion have been evaluated, yet other than supportive measures, no effective therapy has been identified.
Brandon K, Wills +3 more
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The action of silybin on the mouse liver in alpha-amanitine poisoning.
Arzneimittel-Forschung, 1979Histochemical and histoenzymological studies were carried out on liver slices from mice which had received alpha-amanitine two days previously, some of which had been treated with silybin, and from control mice. The toxin produced certain changes in the activity of the enzymes involved in different metabolic processes, and in the amounts of lipids and ...
J, Choppin, A, Desplaces
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A Rapid and Sensitive HPLC Method for Determination of Alpha Amanitin in Urine
1987Amatoxins contained in Amanita Phalloides and other Amanita species are responsible for almost all fatal human intoxications by mushrooms that occur in Italy and in most of the European countries (about 200 cases in northern Italy every year, 10–15% of mortality)1.
R. Fenoil, R. Alfieri, G. Weisz
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Thioctic Acid in the Treatment of Poisoning. with Alpha-Amanitin
2020F C Bartter +4 more
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Time-dependent effects of alpha-amanitin on blastocyst formation in the mouse.
Journal of embryology and experimental morphology, 1980Early compacting mouse morulae were placed in alpha-amanitin at various times after HCG and the effect of this transcriptional inhibitor during formation of the blastocyst was noted. No cavitation was observed in those embryos transferred into alpha-amanitin before 77 h after HCG but the percentage of cavitation increased dramatically in those embryos ...
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Dimethyl-PGE2 prolongs survival from alpha amanitin
Annals of Emergency Medicine, 1989EA Michelson, SM Schneider
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[Research on the mechanism of cytopathogenic action of alpha-amanitine].
Lo sperimentale, 1967L, Fiume, M, La Placa, M, Portolani
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[Effects of alpha amanitin, the poison of amanita phalloides].
Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 2004O, WIELAND, H E, FISCHER, M, REITER
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