Amanitins: The Most Poisonous Molecules of the Fungal World [PDF]
Molecules, 2023 Among the toxic metabolites of the fungal world, those that, due to their strong biological effect, can seriously (even fatally) damage the life processes of humans (and certain groups of animals) stand out.
János Vetter
exaly +4 more sources
Toxic Effects of Amanitins: Repurposing Toxicities toward New Therapeutics [PDF]
Toxins, 2021 The consumption of mushrooms has become increasingly popular, partly due to their nutritional and medicinal properties. This has increased the risk of confusion during picking, and thus of intoxication.
Brendan Le Daré +2 more
exaly +4 more sources
Acute Liver Failure Caused by Amanita phalloides Poisoning [PDF]
International Journal of Hepatology, 2012 Mushroom poisoning is a relatively rare cause of acute liver failure (ALF). The present paper analyzes the pathogenesis, clinical features, prognostic indicators, and therapeutic strategies of ALF secondary to ingestion of Amanita phalloides, which ...
Luca Santi +5 more
doaj +5 more sources
The MSDIN family in amanitin-producing mushrooms and evolution of the prolyl oligopeptidase genes [PDF]
IMA Fungus, 2018 The biosynthetic pathway for amanitins and related cyclic peptides in deadly Amanita (Amanitaceae) mushrooms represents the first known ribosomal cyclic peptide pathway in the Fungi.
Hong Luo +6 more
doaj +4 more sources
Amanitins in Wild Mushrooms: The Development of HPLC-UV-EC and HPLC-DAD-MS Methods for Food Safety Purposes [PDF]
Foods, 2022 Mushroom poisoning remains a serious food safety and health concern in some parts of the world due to its morbidity and mortality. Identification of mushroom toxins at an early stage of suspected intoxication is crucial for a rapid therapeutic decision ...
Isabel Barbosa +3 more
doaj +2 more sources
Rapid, Sensitive, and Accurate Point-of-Care Detection of Lethal Amatoxins in Urine [PDF]
Toxins, 2020 Globally, mushroom poisonings cause about 100 human deaths each year, with thousands of people requiring medical assistance. Dogs are also susceptible to mushroom poisonings and require medical assistance.
Candace S. Bever +7 more
doaj +2 more sources
Amanita section Phalloideae species in the mediterranean basin: destroying angels reviewed [PDF]
, 2022 31 p.In Europe, amatoxin-containing mushrooms are responsible for most of the deadly poisonings caused by macrofungi. The present work presents a multidisciplinary revision of the European species of Amanita sect.
Alvarado García, Pablo +10 more
core +1 more source
Exploring fungal RiPPs from the perspective of chemical ecology [PDF]
, 2022 Since the initial detection, in 2007, of fungal ribosomally synthesised and post-translationally modified peptides (RiPPs), this group of natural products has undergone rapid expansion, with four separate classes now recognised: amatoxins/phallotoxins ...
Bailey, Andrew M. +2 more
core +2 more sources
Cyclopeptides from Amanita exitialis [PDF]
, 2011 A new cyclic nonapeptide, amanexitide (1), along with the known cyclopeptides, α- and β-amanitins, was isolated from the fruiting bodies of Amanita exitialis, a newly described poisonous mushroom endemic to Guangzhou, Guangdong Province, China. Its amino
Jing-Hua Xue +4 more
core +1 more source
Profiling of Amatoxins and Phallotoxins in the Genus Lepiota by Liquid Chromatography Combined with UV Absorbance and Mass Spectrometry [PDF]
, 2014 Species in the mushroom genus Lepiota can cause fatal mushroom poisonings due to their content of amatoxins such as α-amanitin. Previous studies of the toxin composition of poisonous Lepiota species relied on analytical methods of low sensitivity or ...
Al Shahni +23 more
core +2 more sources