Results 31 to 40 of about 441 (134)

Protective Effect and Mechanism of Rosiglitazone in α‐amanitin‐induced Hepatotoxicity Via Activation of PPAR‐γ/Nrf2 Signaling Pathway

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 2, February 2026.
ABSTRACT α‐amanitin (α‐AMA), the primary lethal toxin of amanita, primarily targets the liver with a high toxicity and a low lethal dose. As the precise mechanism of intoxication is unclear, and specific antidotes are lacking, α‐AMA‐induced liver injury has a high mortality rate.
Fuping Lai, Ya Liao, Jin Wu, Tinggang Wang, Guiyi Zhang, Xiaojun Zhang, Caiyun Xia, Jie Hu, Yuanlan Lu   +8 more
wiley   +1 more source

GLS1‐RNA Polymerase II Axis Mediates Glutamine‐Dependent Hepatoprotective Effects on Alcoholic Liver Disease in High‐Protein Diets

Advanced Science, Volume 12, Issue 45, December 4, 2025.
GLS1 interacts with RNA polymerase II subunits, ROLR2H and POLR2E, resulting in significant suppression of RNA polymerase II activity. Importantly, the investigation demonstrates that high‐protein diets, particularly glutamine, exert protective effects against alcoholic fatty liver through GLS1‐RNA polymerase II axis.
Wenbiao Wu, Haowen Jiang, Yichang Liu, Chang Peng, Hanlin Wang, Wenhua Yang, Zan Lyu, Yan Sun, Huan Ma, Hongyu Gu, Weijuan Kan, Liya Jing, Tiancheng Dong, Chunmei Xia, Saifei Lei, Rui Wu, Jinlong Li, Jia Li   +17 more
wiley   +1 more source

A radioimmunoassay for amanitin

FEBS Letters, 1975
Faulstich, H., Trischmann, H., Zobeley, S.   +2 more
openaire   +3 more sources

A label-free electrochemical immunosensor based on decorated cellulose nanofibrous membrane for point-of-care diagnosis of amanitin poisoning via human urine. [PDF]

Lab Chip, 2023
El-Moghazy AY, Amaly N, Nitin N, Sun G.
europepmc   +1 more source

Mushroom Poisoning: A Rare Etiology of Acute Liver Failure. [PDF]

Cureus, 2023
Mohammed HMI, Ahmad F.
europepmc   +1 more source

Genes and evolutionary fates of the amanitin biosynthesis pathway in poisonous mushrooms. [PDF]

Proc Natl Acad Sci U S A, 2022
Luo H, Hallen-Adams HE, Lüli Y, Sgambelluri RM, Li X, Smith M, Yang ZL, Martin FM.   +7 more
europepmc   +1 more source

Amanita Section Phalloideae Species in the Mediterranean Basin: Destroying Angels Reviewed. [PDF]

Biology (Basel), 2022
Alvarado P, Gasch-Illescas A, Morel S, Dagher-Kharrat MB, Moreno G, Manjón JL, Carteret X, Bellanger JM, Rapior S, Gelardi M, Moreau PA.   +10 more
europepmc   +1 more source

The occurrence of ansamers in the synthesis of cyclic peptides. [PDF]

Nat Commun, 2022
Yao G, Kosol S, Wenz MT, Irran E, Keller BG, Trapp O, Süssmuth RD.   +6 more
europepmc   +1 more source

Amanita phalloides-Associated Liver Failure: Molecular Mechanisms and Management. [PDF]

Int J Mol Sci
Kayes T, Ho V.
europepmc   +1 more source

Phylogenetic analysis of the distribution of deadly amatoxins among the little brown mushrooms of the genus Galerina. [PDF]

PLoS One, 2021
Landry B, Whitton J, Bazzicalupo AL, Ceska O, Berbee ML.   +4 more
europepmc   +1 more source