Results 31 to 40 of about 486 (156)

Demystifying fungal systematics: A gateway to fungal literacy and societal/ecological relevance through familiar species

PLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 499-515, March 2026.
Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.
Anna Vaiana, Francis Martin, Rasmus Kjøller, Toby Spribille, Garima Singh   +4 more
wiley   +1 more source

Introns as Protective Buffers Against Transposable Elements Invasion During Genome Gigantism in a Newt

Genes to Cells, Volume 31, Issue 2, March 2026.
In the giant Pleurodeles waltl genome, introns serve as “structural buffers,” absorbing transposable elements (TEs) to protect coding exons. While this enables “gene body inflation,” persistent TE accumulation eventually leads to transcriptional silencing and functional collapse, or “burst,” of the gene architecture.
Kazuto Bou, Kiyokazu Agata
wiley   +1 more source

Protective Effect and Mechanism of Rosiglitazone in α‐amanitin‐induced Hepatotoxicity Via Activation of PPAR‐γ/Nrf2 Signaling Pathway

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 2, February 2026.
ABSTRACT α‐amanitin (α‐AMA), the primary lethal toxin of amanita, primarily targets the liver with a high toxicity and a low lethal dose. As the precise mechanism of intoxication is unclear, and specific antidotes are lacking, α‐AMA‐induced liver injury has a high mortality rate.
Fuping Lai, Ya Liao, Jin Wu, Tinggang Wang, Guiyi Zhang, Xiaojun Zhang, Caiyun Xia, Jie Hu, Yuanlan Lu   +8 more
wiley   +1 more source

Chemical and pharmacological study of higher fungi. II. Comparative investigation of carpophores of some Nematoloma species: chemical composition and cultural characteristics [PDF]

, 1996
International audienceCarpophores of Nematoloma fasciculare, N. capnoides and N. sublateritium were screened by thin layer chromatography and qualitative chemical reactions in order to detect polyols, free sugards, amino acides, phenolic acids ...
Mnatzakanyan, V. A., Badalyan, Susanna M., Garibova, L. V., Andary, Claude, Doko, Lucette, Jacob, Marcel, Rapior, Sylvie, Arutunyan, L. S.   +7 more
core   +2 more sources

Xenobiotic-induced hepatotoxicity : metabolism studies and mechanisms of action [PDF]

, 2021
La toxicité hépatique des xénobiotiques constitue un sujet extrêmement riche, au vu des multiples mécanismes et acteurs impliqués. Ce travail de toxicologie translationnelle a pour but d’améliorer la compréhension des mécanismes hépatotoxiques de l ...
Le Daré, Brendan
core  

GLS1‐RNA Polymerase II Axis Mediates Glutamine‐Dependent Hepatoprotective Effects on Alcoholic Liver Disease in High‐Protein Diets

Advanced Science, Volume 12, Issue 45, December 4, 2025.
GLS1 interacts with RNA polymerase II subunits, ROLR2H and POLR2E, resulting in significant suppression of RNA polymerase II activity. Importantly, the investigation demonstrates that high‐protein diets, particularly glutamine, exert protective effects against alcoholic fatty liver through GLS1‐RNA polymerase II axis.
Wenbiao Wu, Haowen Jiang, Yichang Liu, Chang Peng, Hanlin Wang, Wenhua Yang, Zan Lyu, Yan Sun, Huan Ma, Hongyu Gu, Weijuan Kan, Liya Jing, Tiancheng Dong, Chunmei Xia, Saifei Lei, Rui Wu, Jinlong Li, Jia Li   +17 more
wiley   +1 more source

Xénobiotiques hépatotoxiques : études de métabolisme et mécanismes d’action [PDF]

, 2021
Xenobiotic-induced hepatotoxicity is an extremely rich subject, given the multiple mechanisms and actors involved. This translational work aims to improve ethanol and amanitins (powerful fungal toxins) hepatotoxic mechanisms understanding, in order to ...
Le Daré, Brendan
core  

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +28 more
wiley   +1 more source

MiR‐1 Is Regulated by Hydrogen Peroxide via MAPK and Limits Cell Migration and Invasion

Environmental Toxicology, Volume 40, Issue 11, Page 1249-1260, November 2025.
ABSTRACT MicroRNA‐1 (miR‐1) is a conserved microRNA that is highly expressed in skeletal and cardiac muscle tissues. Moreover, miR‐1 regulates genes and has critical roles in cell migration and invasion. Downregulation of miR‐1 has been found in many pathologies of numerous organs, including the lungs.
Maricica Pacurari, Irmanecia Cox, Ibrahim Farah   +2 more
wiley   +1 more source

Acute liver failure caused by mushroom poisoning: a case report and review of the literature

International Medical Case Reports Journal, 2013
Abdulsamet Erden,1 Kübra Esmeray,1 Hatice Karagöz,1 Samet Karahan,1 Hasan Hüseyin Gümüsçü,1 Mustafa Basak,1 Ali Çetinkaya,1 Deniz Avci,1 Orhan Kürsat Poyrazoğlu2 1Internal Medicine Department ...
Erden A, Esmeray K, Karagöz H, Karahan S, Gümüşçü HH, Başak M, Çetinkaya A, Avci D, Poyrazoglu OK   +8 more
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