Results 21 to 30 of about 600 (173)
Co-localization of Amanitin and a Candidate Toxin-Processing Prolyl Oligopeptidase in Amanita Basidiocarps [PDF]
, 2010 Fungi in the basidiomycetous ge nus Amanita owe their high mammalian toxicity to the bicyclic octapeptide amatoxins such as ∝-amanitin. Amatoxins and the related phallotoxins (such as the heptapeptide phalloidin) are encoded by members of the “MSDIN”
Hallen-Adams, Heather E +3 more
core +2 more sources
Anti-BCMA novel therapies for multiple myeloma [PDF]
, 2023 Recent advances in multiple myeloma therapy have increased the depth of response and ultimately survivals; however, the prognosis remains poor. The BCMA antigen is highly expressed in myeloma cells, thus representing a target for novel therapies. Several
Bocchia, Monica +7 more
core +1 more source
The most widely recognized mushroom: Chemistry of the genus Amanita. [PDF]
, 2005 Many review papers have been published on mushrooms of the genus Amanita, as these are well known to both scientific and lay audiences, probably due to the toxic and/or hallucinogenic properties of some species.
NC DOCKS at The University of North Carolina at Greensboro +1 more
core +1 more source
Cyclopentadienon-hydrazon [PDF]
, 2023 Durch Alkylierung von Dimethyl-nitrosamin mit Dimethylsulfat erhielten wir Trimethyl-nitros-immonium-methosulfat (I) [1]
Hafner, Klaus, Wagner, K.
core +1 more source
Clinical Toxicology, 2022 BACKGROUND AND AIMS: Amanita phalloides poisoning causes severe liver damage which may be potentially fatal. Several treatments are available, but their effectiveness has not been systematically evaluated. We performed a systematic review to investigate the effect of the most commonly used therapies: N-acetylcysteine (NAC), benzylpenicillin (PEN), and ...
Tan, Jia Lin +5 more
openaire +1 more source
CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma [PDF]
, 2020 Cancer cells commonly develop resistance to immunotherapy by loss of antigen expression. Combinatorial treatments that increase levels of the target antigen on the surface of cancer cells have the potential to restore efficacy to immunotherapy.
Abarientos, Anthony B +16 more
core +1 more source
Improved Analytical Technologies for the Detection of Natural Toxins and Their Metabolites in Food [PDF]
, 2021 Food, by nature, is a biological substrate and is therefore capable of supporting the growth of microbials that are potential producers of toxic compounds. Among them mycotoxins, marine biotoxins, plant toxins, cyanogenic glycosides, and toxins occurring
core +1 more source
Aflatoxin in commercial poultry feeds and clinico-pathological manifestation of aflaxoxicosis in poultry in Southwest, Nigeria [PDF]
, 2016 Aflatoxin remains the most studied mycotoxin with aflatoxin B1 making up 66 to 82% of total aflatoxin found in feed. In poultry, it can cause high production losses and vaccine failure resulting from its hepatocarcinogenic, mutagenic, teratogenic and ...
Adebowale, T.K., Daodu, O.B.
core +2 more sources
Antiproliferative Effect of pHLIP-Amanitin
Biochemistry, 2013 Toxins could be effective anticancer drugs, if their selective delivery into cancer cells could be achieved. We have shown that the energy of membrane-associated folding of water-soluble membrane peptides of the pHLIP (pH low insertion peptide) family could be used to move cell-impermeable cargo across the lipid bilayer into the cytoplasm of cancer ...
Moshnikova, Anna +3 more
openaire +4 more sources
Prenatal Diagnosis, EarlyView.ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde +4 more
wiley +1 more source