Przesiewowa metoda badania krwi oraz moczu na obecność związków toksycznych naturalnie występujących w grzybach metodą LC-MS [PDF]
Analysis of biological material collected during autopsies and even from living humans for the presence of amanitins and other fungal toxins remains a challenge in forensic toxicology.
Zuba, Dariusz +2 more
core +1 more source
Dermal absorption and toxicity of alpha amanitin in mice [PDF]
Yaykasli, Kursat/0000-0001-7550-6370; Kaya, Ertugrul/0000-0003-0081-682XWOS: 000336731700015PubMed: 23763309The fungus Amanita phalloides is known to contain two main groups of toxins: amanitins and phallotoxins.
Kaya, Ertuğrul +8 more
core +3 more sources
Evaluation and comparison of alpha- and beta-amanitin toxicity on MCF-7 cell line [PDF]
Background/aim: Alpha- and beta-amanitins are the main toxins of the poisonous Amanita phalloides mushroom. Although there are many studies available concerning alpha-amanitin, there are limited data about beta-amanitin in the literature. Therefore, this
Kaya, Ertuğrul +6 more
core +2 more sources
The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan +8 more
wiley +1 more source
Predator–Microbe Dynamics Inform Strategies for Robust Synthetic Community Assembly
This Review introduces ecological principles of predator–prey interactions as a new dimension in SynCom design. By linking microbial defence traits, encounter dynamics, and adaptive buffering, it outlines a framework for constructing predator‐resistant synthetic communities with enhanced resilience, stability, and functional performance under natural ...
Eleonora Egidi, Uffe N. Nielsen
wiley +1 more source
Über die Inhaltsstoffe des grünen Knollenblätterpilzes, XLIV Die Konfiguration der hydroxylierten Isoleucine der Amatoxine [PDF]
Durch Röntgenstrukturanalyse seines γ-Lacton-hydrobromids wurde die absolute Konfiguration jenes γ-Hydroxyisoleucins, das im γ-Amanitin vorkommt, als (2S,3R,4S)-2-Amino-3-methyl-4-hydroxyvaleriansäure (6) bestimmt. Diese im Gegensatz zu früher2) als 4R-2
Eberhard Breitmaier +17 more
core +1 more source
Convergence and parallelism in the evolution of plant metabolism
Similar traits in different organisms may originate from shared ancestry or evolve independently. The terminology used to define phenotypic similarity is often confusing. This review attempts to clarify the definitions and present examples from plant domestication and specialized metabolism to explain how complex traits evolve repeatedly in plants ...
Federico Scossa +4 more
wiley +1 more source
Transposable elements: Functional aspects and applications as drivers of crop innovation
Abstract Transposable elements (TEs), which were once relegated to the status of genomic parasites, are today accepted as important agents of plant genome evolution and adaptation. This review integrates evidence pointing to their dual function as drivers of genetic diversity and instability, with a focus on their contribution to phenotypic innovation,
Flávia Layse Belém Medeiros +12 more
wiley +1 more source
Upstream CB1R Regulation of β‐Adrenergic Memory Consolidation
ABSTRACT Object recognition memory (ORM) plays a key role in identifying familiar items and encoding episodic information. ORM consolidation depends on β‐adrenergic receptor (βAR) signaling and is associated with increased BDNF expression in the dorsal hippocampus.
Janine I. Rossato +9 more
wiley +1 more source
A universal method for the identification of genes encoding amatoxins and phallotoxins in poisonous mushrooms [PDF]
Background. As the currently known diagnostic DNA targets amplified in the PCR assays for detection of poisonous mushrooms have their counterparts in edible species, there is a need to design PCR primers specific to the genes encoding amanitins and ...
Kotlowski, R., Woloszyn, A.
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