Results 131 to 140 of about 1,161,913 (375)

Efficacy and safety of fruquintinib combined with albumin‐bound paclitaxel as second‐line therapy for advanced gastric cancer following failure of PD‐1 inhibitor‐containing treatment (TACTIC GC‐01): A phase II single‐arm study

International Journal of Cancer, EarlyView.
What's New? Anti‐angiogenic drugs have shown promising efficacy as a second‐line treatment for advanced gastric cancer. However, it remains unclear how alterations in the tumor microenvironment following first‐line immunotherapy may impact tumor angiogenesis and influence subsequent therapeutic outcomes. This single‐arm study prospectively explored the
Xiaoting Ma, Kai Ou, Xiu Liu, Biyang Cao, Wenwei Yang, Jingyu Lu, Letian Zhang, Qi Wang, Lizhen Gao, Zhichao Jiang, Yongkun Sun, Lin Yang   +11 more
wiley   +1 more source

Трофічні преференції акаридієвих кліщів (Acariformes, Astigmata) – шкідників запасів олійних та зернових культур [PDF]

, 2016
Досліджено видові комплекси акаридієвих кліщів як шкідників запасів олійних та зерно-вих культур господарських прибудов та зерносховищ Житомирської області.
Оксентюк, Я. Р.
core  

Oat β‐Glucan and Galactooligosaccharides Influence Gallstone Formation by Modulating the Gut Microbiota, Particularly Desulfovibrionales

iMetaMed, EarlyView.
Oat β‐glucan and galactooligosaccharides influence the formation of gallstones by modulating the gut microbiota, particularly the abundance of Desulfovibrionales. The primary mechanism involves metabolic byproducts associated with Desulfovibrionales inhibiting hepatic bile acid synthesis via both the hepatic FXR–SHP and intestinal FXR–FGF15 signaling ...
Liang Tian, Yanyan Lin, Ping Yue, Long Gao, Leiqing Wang, Chongfei Huang, Jinyu Zhao, Ningzu Jiang, Jiahui xi, Haidong Ma, Zhen Liu, Ruyang Zhong, Wenkang Fu, Ningning Mi, Mingzhen Bai, Bodong Zhang, Lunzhi Dai, Jiang Li, Hu Chen, Jinqiu Yuan, Wenbo Meng   +20 more
wiley   +1 more source

Integrated transcriptomic and metabolomic analyses delineate the biosynthetic pathways of functional components in maturing Akebia trifoliata fruit

Food Chemistry: Molecular Sciences
This study integrates transcriptomic and metabolomic analyses across five developmental stages of Akebia trifoliata, a climacteric fruit, to map the molecular mechanisms of fruit maturation.
Mian Faisal Nazir, Tianjiao Jia, Chen Feng, Edgar Manuel Bovio-Zenteno, Yi Zhang, Longyu Dai, Jie Xu, Yafang Zhao, Shuaiyu Zou   +8 more
doaj   +1 more source

A personal 360° view of applications of ‘biomimetic’ molecular recognition

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

Temperature adaptations in psychrophilic, mesophilic and thermophilic chloride-dependent alpha-amylases.

Biochimie, 2012
Alexandre Cipolla, F. Delbrassine, J. Da Lage, G. Feller   +3 more
semanticscholar   +1 more source

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni, Styliani Kalantzi, Theopisti Lymperopoulou, Andromachi Tzani, Georgios Stavropoulos, Anastasia Detsi, Diomi Mamma   +6 more
wiley   +1 more source

Subsite mapping of enzymes. Application of the depolymerase computer model to two alpha-amylases.

Biochemical Journal, 1976
J. D. Allen, J. Thoma
semanticscholar   +1 more source

Optimized production, purification and characterization of alpha amylase by Brevibacterium linens DSM 20158, using bio-statistical approach [PDF]

, 2011
Khadija Shabbiri, Ahmad Adnan, Bushra Noor, Sania Jamil   +3 more
openalex   +1 more source

Reduced Dietary Protein Induces Changes in the Dental Proteome

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs, Christopher J. Percival, Natasha S. Vitek   +2 more
wiley   +1 more source