Results 51 to 60 of about 49,741 (289)
Advanced Science, EarlyView.This study introduces a dendrimer‐peptide conjugate platform (G7‐pPDL1) for avidity‐based capture of PD‐L1‐expressing exosomes. The system exhibits enhanced binding kinetics and exosome capture efficiency, enabling accurate prediction of immunotherapy outcomes.
Jiah Lee +15 more
wiley +1 more source
Advanced Science, EarlyView.High PIVKA‐II expression in HCC correlates with resistance to anti‐PD‐1 plus lenvatinib, driven by an immunosuppressive TME. NQO1/p65/CXCL12 axis recruits Tregs to promote resistance to anti‐PD‐1 plus lenvatinib in HCC with high PIVKA‐II expression.
Biao Gao +18 more
wiley +1 more source
Pushing Biomolecule Detection Limit With Graphene Field‐effect Transistor Biosensors
Advanced Electronic Materials, EarlyView.Graphene knows your health! This work presents a comprehensive overview of recent advances in graphene field‐effect transistor (GFET) biosensors for ultrasensitive biomolecule detection. How device engineering, high‐mobility graphene synthesis, and tailored surface chemistry push detection limits is highlighted, while discussing emerging strategies ...
Co Dang Pham +4 more
wiley +1 more source
Alpha-Fetoprotein (AFP): Solved and Unsolved Problems
McGill Journal of Medicine, 2020 N ...
Garry Abelev, Natalia Lazarevich
doaj +1 more source
The Relationship between Preeclampsia and Quadruple Screening Test in Nuliparous [PDF]
Patient Safety and Quality Improvement Journal, 2017 Introduction: Early diagnosis and prediction of preeclampsia needs appropriate obstetric care. Preeclampsia predicting methods are important. This study was designed to determine the correlation between preeclampsia and quadruple screening test in the ...
Farnaz Zand Vakili +3 more
doaj +1 more source
Hereditary persistence of alpha-fetoprotein
Chinese Journal of Cancer Research, 1994 A proband with persistently elevated AFP levels ranging between 21-129 ng/ml with median of 90 ng/ml has been found and observed for 1 year. Family studies have revealed that his father had had persistent AFP elevation for 4 years, ranging from 46 to 198.2 ng/ml, with median level of 93 ng/ml. His brother also has elevated AFP level.
Liu Jian, Zhou Xingren, Feng Yizheng
openaire +3 more sources
Annals of Gastroenterological Surgery, EarlyView.This study aims to elucidate prognostic outcomes of hepatectomy versus RFA for primary 2–3 cm HCC. Hepatectomy may offer superior prognostic benefits, especially in those with elevated AFP levels. The local recurrence rate in hepatectomy is significantly lower than RFA.
Yuki Kitano +8 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Aim Serum tumor markers are helpful for diagnosis, monitoring treatment outcomes, and prognosis. However, their clinical utility for esophageal squamous cell carcinoma (ESCC) and gastric cancer (GC) remains unclear. This study aimed to comprehensively evaluate recent studies on serum tumor markers in ESCC and GC.
Yasunori Matsumoto +2 more
wiley +1 more source
Prognostic roles of pathology markers immunoexpression and clinical parameters in Hepatoblastoma
Journal of Biomedical Science, 2017 Background Hepatoblastoma, a leading primary hepatic malignant tumor in children, is originated from primitive hepatic stem cells. We aimed to elucidate the relationships between the histological distribution of β-catenin and hepatic stem cell markers ...
Jia-Feng Wu +6 more
doaj +1 more source
Intelligent Theranostic Systems Enabled by Aggregation‐Induced Emission in Precision Medicine
Aggregate, EarlyView.Aggregation‐induced emission (AIE) luminogens are driving a new generation of intelligent theranostic systems that integrate high‐fidelity imaging and multifunctional therapy. This review highlights how AIEgens, through restriction of intramolecular motion (RIM), enable deep‐tissue NIR‐II imaging, ultrasensitive biosensing, CRISPR‐assisted gene ...
Qinqin Huang +7 more
wiley +1 more source