Results 61 to 70 of about 948,383 (242)

Table_1_Discovery of Alpha-Gal-Containing Antigens in North American Tick Species Believed to Induce Red Meat Allergy.xlsx

, 2019
Development of specific IgE antibodies to the oligosaccharide galactose-α-1, 3-galactose (α-gal) following tick bites has been shown to be the source of red meat allergy. In this study, we investigated the presence of α-gal in four tick species: the lone-
Guha Dharmarajan (392358), Shailesh Choudhary (6710063), Stephanie A. Archer-Hartman (6710060), Shahid Karim (191874), Scott P. Commins (6710057), Parastoo Azadi (223686), Gary Crispell (3565673)   +6 more
core   +1 more source

Alpha Gal in the Preoperative Environment [PDF]

, 2023
Background: Alpha gal syndrome (AGS) is an allergy acquired from the bite of the lone star tick. This allergy manifests as a sensitivity to red meat, medicines, and implants derived from mammalian sources.
Everding, Grant, NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

Advanced Science, EarlyView.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang, Yu Geng, Xinyu Guo, Chen Wang, Yongjing Sun, Luqi Liu, Li Liu, QianQian Gao, XinFang Zhu, Hongxiang Cao, Gengshuo Zhang, Yunxia Liu, Guobin Zhang, Baoyin Chen, Jinfei Zhang, Xin Hou, Xiaoming Li, Dajian Zhang   +17 more
wiley   +1 more source

Molecular Factors Involved in Tick-Bite Mediated Allergy to the Carbohydrate Alpha-Gal [PDF]

, 2023
Red meat allergy aka α-Gal allergy is a delayed allergic response occurring upon consumption of mammalian meat and by-products. Patients report eating meat without any problems for several years before developing the allergy.
CHAKRAPANI, Neera
core   +1 more source

Alpha-Gal-containing biologics and anaphylaxis

Allergology International, 2019
Cetuximab, the IgG1 subclass chimeric mouse-human monoclonal antibody biologic that targets the epidermal growth factor receptor (EGFR), is used worldwide for the treatment of EGFR-positive unresectable progressive/recurrent colorectal cancer and head ...
Yuko Chinuki, Eishin Morita
doaj   +1 more source

Table_2_Discovery of Alpha-Gal-Containing Antigens in North American Tick Species Believed to Induce Red Meat Allergy.xlsx

, 2019
Development of specific IgE antibodies to the oligosaccharide galactose-α-1, 3-galactose (α-gal) following tick bites has been shown to be the source of red meat allergy. In this study, we investigated the presence of α-gal in four tick species: the lone-
Guha Dharmarajan (392358), Shailesh Choudhary (6710063), Stephanie A. Archer-Hartman (6710060), Shahid Karim (191874), Scott P. Commins (6710057), Parastoo Azadi (223686), Gary Crispell (3565673)   +6 more
core   +1 more source

TPI1 Loss Triggers a Metabolite‐Driven Mitochondrial Redox Vulnerability via the SARM1–cADPR–Ca2+ Axis

Advanced Science, EarlyView.
Metabolite‐driven redox stress governs cancer cell senescence. TPI1 deficiency elevates DHAP, initiating SARM1‐dependent cADPR‐Ca2+ release. Mitochondrial ROS surge subsequently induces DNA damage and senescence, offering a conserved therapeutic target in multiple cancers.
Chunyu Liu, Shun Wu, Chuang Wang, Zirui Zhou, Tianwei Cai, Wen Tao, Shidong Zuo, Chi Zhang, Yuhao Dong, Yi Feng, Qingbo Huang, Baojun Wang, Xin Ma, Haoli Ma, Xu Zhang, Yan Huang   +15 more
wiley   +1 more source

Data_Sheet_1_Discovery of Alpha-Gal-Containing Antigens in North American Tick Species Believed to Induce Red Meat Allergy.docx

, 2019
Development of specific IgE antibodies to the oligosaccharide galactose-α-1, 3-galactose (α-gal) following tick bites has been shown to be the source of red meat allergy. In this study, we investigated the presence of α-gal in four tick species: the lone-
Guha Dharmarajan (392358), Shailesh Choudhary (6710063), Stephanie A. Archer-Hartman (6710060), Shahid Karim (191874), Scott P. Commins (6710057), Parastoo Azadi (223686), Gary Crispell (3565673)   +6 more
core   +1 more source

Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila

Advanced Science, EarlyView.
While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li, Haimin Chen, Gangqi Fang, Dongxiang Wei, Hongyun Wu, Chen Chen, Song Hong, Chengshu Wang   +7 more
wiley   +1 more source

Identification of Alpha-Gal glycolipids in saliva of Lone-Star Tick (Amblyomma americanum)

Ticks and Tick-Borne Diseases
Alpha-Gal Syndrome (AGS) is a delayed allergic reaction triggered by IgE antibodies targeting galactose-α-1,3-galactose (α-gal), prevalent in red meat.
Surendra Raj Sharma, Sabir Hussain, Shailesh K. Choudhary, Scott P. Commins, Shahid Karim   +4 more
doaj   +1 more source