Results 1 to 10 of about 2,027,296 (190)

Tick salivary gland extract induces alpha‐gal syndrome in alpha‐gal deficient mice [PDF]

Immunity, Inflammation and Disease, 2021
Introduction Alpha‐gal syndrome (AGS) is characterized by delayed hypersensitivity to non‐primate mammalian meat in people having specific immunoglobulin E (sIgE) to the oligosaccharide galactose‐alpha‐1,3‐galactose.
Shailesh K. Choudhary, Shahid Karim, Onyinye I. Iweala, Shivangi Choudhary, Gary Crispell, Surendra Raj Sharma, Claire T. Addison, Mike Kulis, Brian H. Herrin, Susan E. Little, Scott P. Commins   +10 more
doaj   +3 more sources

Nutritional considerations for alpha-gal syndrome: a mini-review [PDF]

Frontiers in Allergy
Alpha-gal syndrome (AGS) is an immunoglobulin E-mediated sensitivity to galactose-alpha-1,3-galactose (“alpha-gal”), an oligosaccharide found in non-primate, mammalian-derived foods and products as well as some plant-based ingredients.
Abbigail Pace, Heather Norman-Burgdolf, Anna Cason   +2 more
doaj   +3 more sources

Alpha-gal syndrome and the gastrointestinal reaction: a narrative review [PDF]

Frontiers in Allergy
Gastrointestinal (GI) disturbances such as abdominal pain, nausea, and diarrhea are infrequently attributed to food allergies as an initial diagnosis in the absence of more traditional allergic reactions like hives, angioedema, or anaphylaxis.
Susan B. H. Propst, Dorothea K. Thompson, Dorothea K. Thompson   +2 more
doaj   +4 more sources

Single-cell mRNA analysis and surface marker expression profiling of circulating immune cells in humans with alpha-gal syndrome [PDF]

Frontiers in Immunology
IntroductionAlpha-gal syndrome (AGS) is an IgE-mediated allergy to the oligosaccharide galactose-alpha-1,3-galactose (alpha-gal). Alpha-gal is found in the tissues of non-catarrhine mammals, and the characteristic delayed reactions are caused by the ...
Shailesh K. Choudhary, Scott P. Commins, Scott P. Commins, Scott P. Commins   +3 more
doaj   +4 more sources

Evolution of alpha-Gal synthesis - a growing risk for alpha Gal syndrome [PDF]

Annals of Medicine
Background Alpha-Gal syndrome (AGS) is a growing burden worldwide associated with arthropods and allergies with pathologies such as urticaria, digestive and anaphylactic reactions. These reactions commonly appear 2–6 h after consumption of mammalian meat
Rita Vaz-Rodrigues, José de la Fuente
doaj   +2 more sources

Tick Saliva and the Alpha-Gal Syndrome: Finding a Needle in a Haystack

Frontiers in Cellular and Infection Microbiology, 2021
Ticks and tick-borne diseases are significant public health concerns. Bioactive molecules in tick saliva facilitate prolonged blood-feeding and transmission of tick-borne pathogens to the vertebrate host.
Surendra Raj Sharma, Shahid Karim
doaj   +3 more sources

Perioperative Considerations for Alpha-Gal Syndrome: A Literature Review and Single-Center Experience in a Highly Endemic Area [PDF]

Diseases
Alpha-gal syndrome (AGS) is an acquired allergy characterized as a delayed hypersensitivity reaction to the galactose-alpha-1,3-galactose carbohydrate, which is present on mammalian meat.
Seth Greenspan, Michele Branigan, Naomi Nguyen, Saba Gulzar, Stephen Probst, Meng Wang   +5 more
doaj   +2 more sources

Current and Future Strategies for the Diagnosis and Treatment of the Alpha-Gal Syndrome (AGS)

Journal of Asthma and Allergy, 2022
Rita Vaz-Rodrigues,1 Lorena Mazuecos,1 José de la Fuente1,2 1SaBio (Health and Biotechnology), Instituto de Investigación en Recursos Cinegéticos IREC (CSIC-UCLM-JCCM), Ciudad Real, 13005, Spain; 2Department of Veterinary Pathobiology, Center for ...
Vaz-Rodrigues R, Mazuecos L, de la Fuente J   +2 more
doaj   +2 more sources

A case of alpha-gal syndrome: Recall urticaria and 10 years of measurements of IgE to galactose-α-1,3-galactose

Journal of Allergy and Clinical Immunology: Global
Alpha-gal IgE level can change rapidly. Reassessment of a patient’s alpha-gal IgE level may be helpful in the patient’s clinical follow-up. Pruritus related to the site of a previous tick bite strengthens the diagnosis of alpha-gal syndrome.
Katja Biering Leth-Møller, PhD, Marianne van Hage, PhD, MD, Allan Linneberg, PhD, MD, Line Lund Kårhus, PhD, MD   +3 more
doaj   +3 more sources

Tick bite-induced alpha-gal syndrome and immunologic responses in an alpha-gal deficient murine model

Frontiers in Immunology
IntroductionAlpha-Gal Syndrome (AGS) is a delayed allergic reaction due to specific IgE antibodies targeting galactose-α-1,3-galactose (α-gal), a carbohydrate found in red meat.
Surendra Raj Sharma, Shailesh K. Choudhary, Julia Vorobiov, Scott P. Commins, Shahid Karim   +4 more
doaj   +3 more sources